Chris T Derk, MD, MS
Rheumatology
Accepting new patients
Sees patients age 18 and up
Penn Rheumatology Perelman
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Penn Medicine Provider

About me

  • Professor of Clinical Medicine (Rheumatology)

Specialize in Systemic Sclerosis ( Scleroderma) and Scleroderma like illnesses; Raynaud's and related conditions; Autoimmune Connective tissue disorders. 

Education and training

  • Medical School: Thomas Jefferson University Sidney Kimmel Medical College
  • Residency: Abington Memorial Hospital
  • Fellowship: Thomas Jefferson University Hospital

What my patients think about me

Average Rating

708 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

November 2025
caring dr.
November 2025
excellent provider.
October 2025
easy to talk with
October 2025
dr derk is the best

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Derk is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Mehmetoglu E, Mummadisetty A, Chatzitofis A, Parperis K, Sandorfi N, Derk CT A systematic review of prevalence and predictors of depression in systemic sclerosis based on the CES-D, BDI and PHQ-9 self-assessment questionnaires , Clin Rheumatol: 2025


Hajnoczky N, Levin LS, Sandorfi N, Derk CT Long-term outcomes of vascular grafting of medium-sized vessels of wrist and hand in systemic sclerosis patients with medication refractory Raynaud's , J Scleroderma Relat Disord : 2025


Parperis K, Papachristodoulou M, Derk C, Psarelis S, Voskarides K, Chatzittofis A. Post-traumatic stress disorder and systemic lupus erythematosus: insights from a systematic review. , Rheumatology: 2025


Aguila T, Madan R, Palmer MB, Derk CT Zebra bodies in kidney biopsy: Drug-induced phospholipidosis in patient with Systemic Lupus Erythematosus , J Rheumatol : 2025


Papchristodoulou E; Kakkoulis L; Chopra R; Derk CT, Parperis K Clinical Features and Treatment Outcomes in Aseptic Abscess Syndrome: A Systematic Review of 104 Cases , ACR Convergence : 2025


GRASP study group Functional NOTCH4 Variants Drive Vasculopathy and Fibrosis in Systemic Sclerosis. , ACR Convergence: 2025


Parperi K, Costi E, Philippou S, Hadi M, Derk CT Efficacy of disease modifying antirheumatic drugs in the treatment of granulomatous mastitis: a systematic review , Rheumatol Int, 44(11): 2024,2371-79


GRASP study group Rare variants in the IL1RAP gene implicate the IL-1 signaling pathway in the pathogenesis of systemic sclerosis in African and European ancestries. , ACR annual scientific meeting, Washington DC: 2024


GRASP study group Admixture mapping and gene-based analysis identifies rare variants in genes in the IL-13 and TGF beta signaling pathways in African Americans with systemic sclerosis , ACR annual scientific meeting, Washington DC: 2024


GRASP study Group TCR motifs identify unique clones in African Americans with systemic sclerosis , ACR annual Scientific meeting, Washington DC : 2024


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