Charu Aggarwal, MD, MPH
Medical Oncology
Accepting new patients
Sees patients age 18 and up
Abramson Cancer Center Perelman 2nd Floor West
Headshot of Charu Aggarwal, MD, MPH
Penn Medicine Provider

About me

  • Physician Leader, Airways Malignancies Research
  • Director, Precision Oncology Innovation, Penn Center for Cancer Care Innovation
  • Section Chief, Head & Neck and Thoracic Cancers, Hematology-Oncology
  • Leslye M. Heisler Professor for Lung Cancer Excellence

Dr. Aggarwal specializes in the management of patients with lung cancer. Her clinical research focus is on the development of novel immunotherapeutic approaches, and the discovery and application of biomarkers to guide therapy and monitor treatment. She serves as the local and national principal investigator for multiple clinical trials focusing on the development of targeted immunotherapy approaches.

Education and training

  • Medical School: Lady Hardinge Medical College
  • Residency: Buffalo General Medical Center
  • Fellowship: Fox Chase Cancer Center

What my patients think about me

Average Rating

181 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

February 2026
dr agarwal is kind , caring and smart and considerate. every time she sees me she gives me a hug
February 2026
took time to address my questions and concerns
January 2026
top notch
January 2026
excellent experience.

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
Dr. Aggarwal is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Barsouk A, Heidlauf A, Goel K, Rushkin L, Anran Huang A, Elghawy O, Yu C, Wang L, Yang D, Kurian M, Reed-Guy L, Sun L, Singh A, Aggarwal C, Cohen RB, Langer C, Marmarelis ME. Osimertinib dose-reduction and survival in 1L EGFR-mutated metastatic non-small cell lung cancer (mNSCLC) , Lung Cancer: 2026


Barber-Rotenberg JS, Haas AR, Aggarwal C, O'Hara M, Hexner E, Pequignot E, Dowd E, Ndeupen S, Thai E, Chen F, Oner BS, Czuczman C, Gonzalez VE, Fraietta JA, Hwang WT, Chew A, Jadlowsky JK, Marshall A, Shea KM, Jiang Y, Cosey A, Ferthio R, Levine BL, Plesa G, Siegel DL, Young RM, Sheppard NC, Albelda SM, June CH, Tanyi JL. Phase 1 study of autologous T cells bearing fully human chimeric antigen receptors targeting mesothelin in mesothelin-expressing cancers , Mol Ther: 2026


Aggarwal C, Ng S, Kamalakar R, Beruti S, Simmons A, Beasley MB. A United States-Based Real-World Study on Biomarker Testing and Rebiopsy Rates Among Patients With Non-Small Cell Lung Cancer Across Lines of Therapy , Clin Lung Cancer: 2026


H. Grover ∙ A. Kumar ∙ M. Krishna ∙ P. Kumari ∙ S. Chandrashekaraiah ∙ A. Chakraborty ∙ J. Chauhan ∙ V. Patil ∙ V.P. Shyamasundar ∙ S. Kulkarni ∙ S. Kapoor ∙ J. Wingrove ∙ Y. Mundkur ∙ T. Patil ∙ C. Aggarwal Cellular Heterogeneity and Tertiary Lymphoid Structure Dynamics Predict Overall Survival in Immune Checkpoint Therapy-Treated NSCLC Patients , Journal of Thoracic Oncology, 20(10): 2025


Singh A, Horng H, Roshkovan L, Hershman M, Cohen EA, Aggarwal C, Carpenter EL, Katz SI, Kontos D. Development of a prognostic multiomic biomarker of progression-free survival in advanced non-small cell lung cancer patients treated with first line immunotherapy , Sci Rep, 15: 2025,34591


Aggarwal C, Desai A, McConnell N, Cadirov N, Gustavsen G, Agarwal A, Chehab N, Kotapati S, Patel N. Clinician Perspectives on Digital and Computational Pathology: Clinical Benefits, Concerns, and Willingness to Adopt , Diagnostics (Basel), 15: 2025,2527


C. Aggarwal, D. Watson, P. Nair, A. Kumar, S. Khandelwal, J. Chauhan, S. Khanna, S. George, A. Dey, M. Patil, N. Ganesh, R. Purushottam, S. Kulkarni, P. G, D.A. Lala, S. Basu, S. Kapoor, M. Castro, J. Wingrove, T. Patil Computational Modeling of Comprehensive Genomic Profiling to Predict Chemotherapy Benefit in Advanced NSCLC , Journal of Thoracic Oncology, 20(10): 2025


N.F. Abdel Karim ∙ C. Aggarwal ∙ A. Kobayashi ∙ C. Pompili ∙ D. Molena ∙ E. Shum ∙ G. Friedrich ∙ H. Wakelee ∙ J.R. Brahmer ∙ L. Woldmann ∙ M. Boron ∙ N. Florez ∙ P. Garrido ∙ R. Shenolikar ∙ S. Peters14 ∙ J. Naidoo ∙ M.L. Hsu ∙ E. Felip Gender Differences in Lung Cancer Diagnosis, Treatment Patterns and Outcomes: A Systematic Literature Review , Journal of Thoracic Oncology, 20(10): 2025


Anagnostou V, Aggarwal C. Toward Response-Adaptive Therapy in Locally Advanced NSCLC: Integrating ctDNA and Radiomics for Risk Stratification , Cancer Discov, 15: 2025,1534-1536


Aggarwal C, Martinez-Marti A, Majem M, Barlesi F, Carcereny E, Chu Q, Monnet I, Sánchez-Hernández A, Dakhil S, Camidge DR, Pillet M, Brown M, Paliompeis C, Dowson A, Cooper ZA, Kumar R, Herbst RS. Durvalumab Alone or Combined With Novel Agents for Unresectable Stage III Non-Small Cell Lung Cancer: Update From the COAST Randomized Clinical Trial , JAMA Netw Open, 8: 2025,e2518440