Charles S. Abrams, MD

Wang, Y., Chen, X., Lian, L., Bach, T.L., Golden, J., Morrisey, E.M., Abrams, C.S. PIP5Kγ is required for cardiovascular and neuronal development , Proceedings of the National Academy of Science (U.S.A.), 104(28): 2007,11748-53

Trivedi, C.M., Luo, Y., Yin, Z., Zhang, M., Floss, T., Goettlicher, M., Ruiz, P., Wurst, W., Ferrari, V., Abrams, C.S., Gruber, P., Epstein, J.A. HDAC2 regulates the cardiac hypertrophic response by modulating GSK3β activity , Nature Medicine, 13: 2007,324-331

Wang, Y., Chen, X., Lian, L., Tang, T., Stalker, T.J., Sasaki, T., Brass, L.F., Choi, J.K., Hartwig, J.H., Abrams, C.S. Loss of PIP5KIβ demonstrates that rapid PIP2 synthesis is required for IP3 formation , Proceedings of the National Academy of Science (U.S.A.), 105: 2008,14064-14069

Pan, W., Choi, S.-C., Wang, H., Qin, Y., Volpicelli-Daley, L., Swan, L., Lucast, L., Khooo, C., Zhang, X., Li, L., Abrams, C.S., Sokol, S.Y., Wu, D. Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation , Science, 321: 2008,1350-1353

Wang, Y., Litvinov, R.I., Chen, X., Lian, L., Bach, T.L., Petrich, B., Monkley, S., Critchley, D., Birnbaum, M.J., Weisel, J.W., Hartwig, J.H., Abrams, C.S. Loss of PIP5Kγ, but not PIP5Kβ, impairs the integrity of the membrane cytoskeleton , J. Clinical Investigation, 118(2): 2008,812-819

Mao, Y.S., Yamaga, M., Zhu, X., Wei, M., Sun, H.-Q., Wang, J., Yun, M., Wang, Y., Di Paolo, G., Bennett, M., Mellman, I.S., Abrams, C.S., De Camilli, P.V., Lu, C.Y., and Yin, H.L. Essential and unique roles of PIP5Kγ and α in Fcγ receptor-mediated phagocytosis J. Cell Biology , Journal of Cell Biology, 184: 2009,281-296

Lian, L., Wang, W., Flick, M., Choi, J., Scott, E., Degen, J., Lemmon, M.A., Abrams, C.S. Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis , Blood, In press: 2009

Min, S.H., Abrams, C.S. Why do phosphatidylinositol kinases have so many isoforms? , Biochemical J, 423(1): 2009,99-108

Volpicelli-Daley, L.A., Lucast, L., Gong, L.-W., Liu, L., Sasaki, J., Sasaki, T., Abrams, C.S., Kanaho, Y., De Camilli, P. Phosphatidylinositol 4-phosphate 5-kinases (PIPKIs) and phosphatidylinositol 4,5 bisphosphate [PI(4,5)P2] synthesis in the brain. , J. Biologic Chemistry: 2010,28708-14

Mitsios, J.V., Prévost, N., Kasirer-Friede, A., Gutierrez, E., Groisman, A., Abrams, C.S., Litvinov, R.I., Zemljic-Harpf, A., Ross, R.S., Shattil, S., J. What is vinculin needed for in platelets? , J. Thrombosis & Haemostasis: 2010,2294-2304