Casey Jo Humbyrd, MD, MBE
Orthopaedic Surgery
Headshot of Casey Jo Humbyrd, MD, MBE
Schedule onlineCall 215-662-3340

Casey Jo Humbyrd, MD, MBE

Orthopaedic Surgery
Accepting new patients
Sees patients age 11 through 79
Penn Orthopaedics Pennsylvania Hospital - Farm Journal Building
View 2 additional locations
Schedule onlineCall 215-662-3340
Headshot of Casey Jo Humbyrd, MD, MBE
Penn Medicine Provider

About me

  • Chief, Foot and Ankle Division
  • Director, Program in Surgical Ethics and Health Policy
  • Vice Chair of Quality and Safety
  • Professor of Orthopaedic Surgery at the Pennsylvania Hospital
  • Associate Professor of Orthopaedic Surgery in Medical Ethics and Health Policy

Dr. Humbyrd specializes in the treatment of post-traumatic arthritis and complex sports injuries of the foot and ankle, as well as foot and ankle deformities and arthritis. She has extensive surgical experience in complex reconstructions, including ankle replacement. She was recognized in the 2025 Mainline Region Top Doctors in Orthopedics: Foot & Ankle surgery.

Penn Foot and Ankle Orthopaedic surgeons and Advanced Practice Providers (APPs) work together to provide comprehensive, patient-centered care. Please note that patients may see an APP before an appointment with me.

 

Watch video featuring Casey Jo Humbyrd, MD, MBE on YouTube

Spoken languages

English
English

Reviews

Average Rating

1584 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
August 2026
she was very helpful and well-informed and made a clear plan
Anonymous
August 2026
dr. humbyrd is a highly accomplished surgeon while also being down to earth.
Anonymous
August 2026
dr. humbyrd was recommended to me by by pcp after a prior surgery resulted in sepsis and possible amputation below the knee of my left leg. dr. humbyrd came to the rescue and saved my leg... and my life. no amount of money or thanks could adequately express my gratitude to her.
Anonymous
August 2026
very knowledgeable. easy to understand

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

PRIMARY LOCATION
215-662-3340
Learn about location
215-662-3340
Learn about location
215-662-3340
Learn about location

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
Dr. Humbyrd is a Penn Medicine physician.

Qualifications and experience

Treatments and conditions

Research

Publications

Humbyrd CJ. Medical Ethics. , AAOS Comprehensive Orthopedic Review, Fourth Edition: 2024

Humbyrd CJ, Taitsman L. Shared Decision-Making in Limb Threatening Trauma. , Orthopaedic Trauma Association Online Textbook, 56(1): 2024,67-74

Jain D, Hsu M, Forsberg J, Humbyrd CJ. Military Patient Perspectives on Limb Reconstruction Versus Amputation for Lower Extremity Trauma. , American Medical Association Medical Student Research Day. National Harbor DC: 2023

Mauch J, Humbyrd CJ, Lin I, Verchler J. Current Ethics of Hand Transplants in Immunocompetent Children. , Plastic Surgery. Austin, TX.: 2023

Zhuang T, Vandal N, Alqazzaz A, Dehghani B, Humbyrd CJ. Utilization of MRI for Ankle Sprains by Insurance Type. , Eastern Orthopaedic Association Annual Meeting. Charleston, SC.: 2023

Humbyrd CJ. Gray Matters—Virtue Ethics in a Value-driven World: Pareto Meets PROMIS. , Clinical Orthopaedics and Related Research, 481(10): 2023,1886-1887

Xu AL, Humbyrd CJ. Strategies for Reducing Opioid Use in Foot and Ankle Surgery. , Orthopaedic Clinics of North America, 54(4): 2023,485-494

Interviewed by Chelsea Cooman Ep 148: Repairing the Achilles tendon, with Dr. Casey Humbyrd , Podcast of the Journal of Orthopaedic and Sports Physical Therapy (JOSPT Insights).: 2023

Jain A, Humbyrd CJ. Ethics of Cost Custodianship and Price Transparency in Orthopaedic Surgery. , Journal of Bone and Joint Surgery, 104(5): 2022,e17

Xu AL, Dunham AM, Enumah ZO, Humbyrd CJ. Patient understanding regarding opioid use in an orthopaedic trauma surgery population: a survey study. , J Orthop Surg Res., 16(1): 2021,736