Penn Medicine Provider
Carla R. Scanzello, MD, PhD

About me

  • Associate Professor of Medicine (Rheumatology) at the Hospital of the University of Pennsylvania
  • Associate Professor of Medicine in Orthopaedic Surgery

Insurance accepted

My Locations

Qualifications and experience

Treatments and Conditions

My research

CR Scanzello, B McKeon, BH Swaim, E DiCarlo, EU Asomugha, V Kanda, A Nair, DM Lee, JC Richmond, JN Katz, MK Crow, SR Goldring. Synovial inflammation in patients undergoing arthroscopic meniscectomy: molecular characterization and relationship with symptoms , Arthritis & Rheumatism, 63(2): 2011,391-400


Q Wang, AL Rozelle, CM Lepus, CR Scanzello, JJ Song, DM Larsen, JF Crish, G Bebek, SY Ritter, TM Lindstrom, I Hwang, HH Wong, L Punzi, A Encarnacion, M Shamloo, SB Goodman, T Wyss-Coray, SR Goldring, R Gobezie, MK Crow, VM Holers DM Lee, WH Robinson Identification of a central role for complement in osteoarthritis , Nature Medicine, 17(12): 2011,1674-9


A Nair, V Kanda, C Bush-Joseph, N Verma, S Chubinskaya, K Mikecz, TT Glant, A-M Malfait, MK Crow, GT Spear, A Finnegan, CR Scanzello Synovial fluid from patients with early osteoarthritis modulates fibroblast-like synoviocyte responses to TLR-4 and TLR-2 ligands via soluble CD14 , Arthritis & Rheumatism, 64(7): 2012,2268-77


CR Scanzello, AS Albert, E DiCarlo, KB Rajan, V Kanda, EU Asomugha, BH Swaim, JN Katz, SR Goldring, JC Richmond, B McKeon. The influence of synovial inflammation and hyperplasia on symptomatic outcomes up to two-years post-operatively in patients undergoing partial meniscectomy. , Osteoarthritis Cartilage, 21(9): 2013,1392-9


Nair A, Gan J, Bush-Joseph C, Verma N, Tetreault MW, Saha K, Margulis A, Fogg L, Scanzello CR. Synovial chemokine expression and relationship with knee symptoms in patients with meniscal tears. , Osteoarthritis Cartilage, 23(7): 2015,1158-64


Sambamurthy Nisha, Nguyen Vu, Smalley Ryan, Xiao Rui, Hankenson Kurt, Gan Justin, Miller Rachel E, Malfait Anne-Marie, Dodge George R, Scanzello Carla R Chemokine receptor-7 (CCR7) deficiency leads to delayed development of joint damage and functional deficits in a murine model of osteoarthritis. , Journal of orthopaedic research, 36(3): 2018,864-87


Sambamurthy Nisha, Zhou Cheng, Nguyen Vu, Smalley Ryan, Hankenson Kurt D, Dodge George R, Scanzello Carla R Deficiency of the pattern-recognition receptor CD14 protects against joint pathology and functional decline in a murine model of osteoarthritis. , PloS One, 13(11): 2018,e0206217


RE Miller, CR Scanzello, A-M Malfait An Emerging Role for Toll-like Receptors at the Neuroimmune Interface in Osteoarthritis , Semin Immunopathol, 41(5): 2019,583-594


S Kolasinski, T Neogi, M Hochberg, C Oatis, GH Guyatt, J Block, L Callahan, C Copenhaver, C Dodge, D Felson, K Geller, W Harvey, G Hawker, E Herzig, K Kwoh, A Nelson, J Samuels, C Scanzello, D White, B Wise, R Altman, D DiRenzo, J Fontanarosa, G Giradi, M Ishimori, D Misra, A Shah, A Shmagel, L Thoma, M Turgunbaev, A Turner, J Reston. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip and Knee. , Arthritis & Rheumatology, 72(2): 2020,220-233


S Bansal, KD Meadows, LM Miller, KS Saleh, JM Patel, BD Stoeckl, EA Lemmon, MW Hast, MH Zgonis, CR Scanzello, DM Elliott, RL Mauck Six Month Outcomes of Clinically Relevant Meniscal Injury in a Large Animal Model , Orthopaedic Journal of Sports Medicine, 9(11): 2021,23259671211035444


View all publications