Brian Litt, MD

Neurology
Sees patients age 16 and up
Penn Neuroscience Center - Neurology
Headshot of Brian Litt, MD
Penn Medicine Provider

About me

  • Perelman Professor of Neurology
  • Professor of Neurology in Neurosurgery

My education and training

  • Medical School: Johns Hopkins University School of Medicine
  • Residency: Johns Hopkins Hospital
  • Fellowship: Johns Hopkins Hospital

Spoken languages

English
English
עברית
Hebrew
Français
French

Reviews

Average Rating

78 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Anonymous
June 2026
brian litt, md, is an excellent clinician with superb interpersonal skills.
Anonymous
June 2026
i've had him for a number of years and i trust him
Anonymous
June 2026
dr litt is a great neurologist and treats his patients well
Anonymous
April 2026
he does a thorough job

Insurance accepted

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Litt is a Penn Medicine physician.

Qualifications and experience

Treatments and conditions

Research

Publications

Pattnaik AR, Xu Z, Ojemann WKS, Aguila CA, Lucas A, Lavelle S, Goldblum Z, Galer PD, Gallagher R, Davis KA, Sinha N, Conrad EC, Litt B. The seizure embedding map: a spatio-temporal transformer for comparing patients by ictal intracranial EEG features at scale , J Neural Eng, 23: 2026,046011


Dong R, Chen Y, Garg R, Averbeck SR, Wun C, Unegbu P, Shankar S, Ahmad S, Jung J, Zahed MA, Zhang D, Gogotsi Y, Takano H, Litt B, Vitale F. Artifact-free, colocalized opto-electrophysiology enabled by a flexible, multimodal interface integrating transparent MXene microelectrodes and microLEDs , Biosens Bioelectron, 304: 2026,118620


Feys O, Walsh KG, Nix KC, Josyula M, Sinha N, Lavelle SB, Wagenaar J, Michalak A, Morrell MJ, Jeschke J, Khambhati AN, Conrad EC, Kleen JK, Litt B, Rao VR, Friedman D, Davis KA. Virtual Responsive Neurostimulation Implantation: From Intracranial Connectivity to Optimized Lead Placement , medRxiv: 2026


Conrad EC, Chang E, Xie K, Aguila CA, Kim J, Shi H, Ojemann WK, Jing J, Westover MB, Sinha SR, Litt B, Davis KA, Cao Q, Ellis CA. Association between Interictal Spike Rate and Seizure Frequency in a Large Epilepsy Cohort , medRxiv: 2026


Davis P, B Tomlinson S, Armstrong C, Conrad EC, Ojemann WKS, Peters J, Litt B, Gilman C, Kennedy BC, Marsh ED. Cortical stimulation reveals effective disconnection of the epileptogenic network at seizure onset , Epilepsia: 2026


Aguila CA, Zhou Z, Lavelle SB, Ojemann WKS, Kim J, Walsh K, Mournani SS, Lucas A, Sinha N, Feys O, Scheid BH, Davis KA, Litt B, Conrad EC. Regional excitability, not epileptic pathology, drives stimulation-evoked interictal spike increases , medRxiv: 2026


Vizcarra JA, Hefter K, Lafontant DE, Duong MT, Ertefaie A, Litt B, Bassett DS, Siderowf A; Parkinson's Progression Markers Initiative. Sex Differences in Fall Frequency, Risk Factors, and Outcomes in Parkinson's Disease: A Cross-Sectional Analysis , Mov Disord Clin Pract: 2026


Kojima J, Shi H, Jaikumar S, Ojemann WKS, Aguila C, Kim J, Ganguly TM, Litt B, Conrad EC. How Much Does the Reduced EEG Montage Matter for Seizure Detection?: A Large-Cohort Simulation Study , medRxiv: 2026


Chen Y, Litt B, Vitale F, Takano H. On-demand seizures facilitate rapid screening of therapeutics for epilepsy , Elife, 13: 2026,RP101859


Haggerty J, Qureshi Q, Gabriel ED, Borges PG, Davis P, Wingel K, Cai J, Sargur K, Kim MJ, Dubey A, Garwood I, Vaz A, Richardson AG, Chen HI, Hammer LH, Gold J, Litt B, Yoshor D, Beauchamp M, Halpern C, Pesaran B, Cajigas I. Thalamus: a real-time system for synchronized, closed-loop multimodal behavioral and electrophysiological data capture , Commun Eng, 5: 2026,93


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