Penn Medicine Provider
Renal Electrolyte and Hypertension
Brenda B. Hoffman, MD
4.9
(234)
Accepting new patients
Sees patients age 18 and up
Penn Renal Electrolyte and Hypertension University City
Schedule onlineCall 800-789-7366

About me

  • Medical Director, Acute Dialysis Program
  • Professor of Clinical Medicine (Renal-Electrolyte and Hypertension)

Education and training

  • Medical School: University of Pennsylvania School of Medicine
  • Residency: Graduate Hospital
  • Fellowship: Hospital of the University of Pennsylvania

What my patients think about me

Average Rating
4.9

234 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

July 2025
5.0
5.0
personable
July 2025
5.0
5.0
she is wonderful! what can i say? keep my return visits and would not do so if she wasn't fantastic!!
July 2025
5.0
5.0
i was impressed with her knowledge and appreciation for my choice to manage the ckd without medication after recognizing my commitment to doing the work to maintain my health.
June 2025
5.0
5.0
she always takes time with patients

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: On the medical staff, but does not have privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
Dr. Hoffman is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Boyle, SM, Jacobs, B, Sayni, FA, Hoffman, B Management of the Dialysis Patient with Sickle Cell Disease , Seminars in Dialysis, 29(1): 2016,62-70

Barbieri J, Seshasai R, Shemash A, Sedrak M, Hoffman B, Alley E Thymic neuroendocrine tumor presenting with the ectopic ACTH syndrome , Journal of Thoracic Oncology, 8(6): 2013,e57-8

Tan A, Hoffman B, Rosas SE Patient perception of risk factors associated with chronic kidney disease morbidity and mortality , Ethnicity and Disease, 20: 2010,106-108

Hoffman BB Peritoneal Dialysis , Current Diagnosis and Treatment in Nephrology and Hypertension, Chapter 51(Section 8): 2009,444-452

Hoffman BB Surgery in the Patient with Kidney Disease , Medical Management of the Surgical Patient 3rd edition, Chapter 18: 2008,605-632

Chen S, Hoffman BB, Jim B, Lee JS, Kopp JB, Ziyadeh FN Tubular cells from TGF-beta 1 knockout mice show decreased fibronectin and blunted hypertrophy in high glucose , Kidney Intl, 65: 2004,1191-1204

Chen S, Lee JS, Hoffman BB, Ziyadeh FN Cultured tubule cells from TGF-beta 1 knockout mice exhibit impaired hypertrophy and fibronectin expression in high glucose , JASN, 14: 2003,128A

Dell M, Hoffman BB, Leonard MB, Ziyadeh FN, Schulman SL Increased urinary transforming growth factor beta-1 (TGF-B1) excretion in children with posterior urethral valves , Urology, 56(2): 2000,311-4

Isono M, Mogyorosi A, Han DC, Hoffman BB, Ziyadeh FN Stimulation of TGF-B type II receptor gene expression in mouse mesangial cells by high glucose and in diabetic kidney , Amer Journal of Physiology, 278: 2000,F830-F838

Ziyadeh FN, Hoffman BB, Han DC, Iglesias-De La Cruz MC, Hong SW, Isono M, Chen S, McGowan TA, Sharma K Long term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal anti transforming growth factor-beta antibody in db/db diabetic mice , PNAS, 97(14): 2000,8015-20