Benedicte Lefebvre, MD
Cardiology
Accepting new patients
Sees patients age 18 and up
Penn Heart and Vascular Center
Penn Medicine Provider

About me

  • Assistant Professor of Clinical Medicine (Cardiovascular Medicine)

Education and training

  • Medical School: McGill University
  • Residency: McGill University

What my patients think about me

Average Rating

66 reviews

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

December 2025
great doctor very intelligent very knowledgeable. very caring.
November 2025
love dr l in cardiology so kind , and prompt with test results. most of all her concern for my health
October 2025
excellent dr takes time explaining my problems
September 2025
she is personable and sincerely concerned about my well being

Insurance accepted

My Locations

Penn Medicine hospital privileges

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Chester County Hospital: Has privileges to treat patients in the hospital.
Dr. Lefebvre is a Penn Medicine physician.

Qualifications and experience

Treatments and Conditions

My research

Abhinav Kandala, Amar Rai, Rahul Penumaka, Nicholas S. Wilcox, Benedicte Lefebvre, Michael G. Fradley Radiomics for the Detection and Prediction of Cardiotoxicity in Patients with Cancer: A Structured Narrative Review , Journal of the American College of Cardiology: 2026


Lefebvre, Scherrer-Crosbie Hematology: Basic Principles and Practice Chapter: Onco-cardiology: Focus on Cardiac Complications of Hematologic Treatments , Textbook: 2026


Lefebvre, Carver European Society of Cardiology, Textbook of Cardiovascular Medicine, 4th Edition , Textbook: 2026


Congying Xia, Amanda M Smith, Bénédicte Lefebvre, Faizi A Jamal, Saro H Armenian, Daniel Koropeckyj-Cox, Liyong Zhang, Peter P Liu, Daniel Landsburg, Amy S Clark, Payal D Shah, Rebecca A Hubbard, Anran Huang, Sophia Golec, Maureen Hewitt, Nicholas S Wilcox, Zhen Chen, Leah Rethy, Wonyoung Jung, Kyunga Ko, Vivek Narayan, Yehoda M Martei, Ninian N Lang, James L Januzzi, G Michael Felker, Bonnie Ky Biomarker-Guided Cardioprotection for Patients Treated With Anthracyclines: A Randomized Clinical Trial , JAMA Network Open, 8(12): 2025


Eva Berlin, Kyunga Ko, Lin Ma, Ian Messing, Casey Hollawell, Amanda M Smith, Neil K Taunk, Vivek Narayan, Jenica N Upshaw, Amy S Clark, Payal D Shah, Hayley Knollman, Saveri Bhattacharya, Daniel Koropeckyj-Cox, Jessica Wang, Nikhil Yegya-Raman, Ivy S Han, Benedicte Lefebvre, Tang Li, Nicholas S Wilcox, Wonyoung Jung, Jinbo Chen, Gary M Freedman, Bonnie Ky Cardiac Effects of Modern Breast Radiation Therapy in Patients Receiving Systemic Cancer Therapy , JACC CardioOncology , 7(3): 2025,219-230


Matthew A Barrett, Biniyam G Demissei, Ray Hu, Amanda M Smith, Gary Freedman, John Plastaras, Steven Feigenberg, Eva Berlin, Hari K Narayan, Benedicte Lefebvre, Marielle Scherrer Crosbie, Michael Fradley, Joseph Carver, Jinbo Chen, Bonnie Ky 3D Echocardiographic Phenotyping of Left Ventricular Mechanics and Function With Contemporary Radiation Therapy , Advances in Radiation Oncolology , 10(7): 2025


Azin Vakilpour, Yulei Cao, Benedicte Lefebvre, Srinivas Denduluri, Amanda M Smith, Marielle Scherrer-Crosbie CARDIOVASCULAR ADVERSE EVENTS AFTER BORTEZOMIB THERAPY IN PATIENTS WITH MULTIPLE MYELOMA: A LARGE REAL-WORLD DATA ANALYSIS , Journal of the American College of Cardiology: 2025


Takeshi Onoue, Andrew H Matthews, Azin Vakilpour, Yu Kang, Bénédicte Lefebvre, Amanda M Smith, Shannon R McCurdy, Michael G Fradley, Joseph Carver, Jesse Chittams, Marielle Scherrer-Crosbie Cardiotoxicity of venetoclax in patients with acute myeloid leukemia: comparison with anthracyclines , Cardio-Oncology , 10(75): 2024


Yu Kang, Benedicte Lefebvre, Ingrid Marti Pamies, Saar I Gill, Abigail G Doucette, Srinivas Denduluri, Amanda M Smith, Shannon McCurdy, Selina Luger, Joseph Carver, Marielle Scherrer-Crosbie Symptomatic Heart Failure and Clonal Hematopoiesis-Related Mutations in Patients With Acute Myeloid Leukemia , The American Journal of Cardiology : 2024


Andy Y Wang, Peter M Rothwell, Jason Nelson, Jeffrey L Saver, Scott E Kasner, John Carroll, Jean-Louis Mas, Geneviève Derumeaux, Gilles Chatellier, Anthony J Furlan, Howard C Herrmann, Peter Jüni, Jong S Kim, Benjamin Koethe, Pil H Lee, Benedicte Lefebvre, Heinrich P Mattle, Bernhard Meier, Mark Reisman, Richard W Smalling, Lars Sondergaard, Jae-Kwan Song, Emanuele Di Angelantonio, Marco DiTullio, Mitchell S V Elkind, Shunichi Homma, Cheryl Jaigobin, Patrik Michel, Marie-Luise Mono, Krassen Nedeltchev, Federica Papetti, Joaquin Serena, Christian Weimar, Linxin Li, Sara Mazzucco, Louise E Silver, David van Klaveren, David E Thaler, David M Kent Patent Foramen Ovale Closure in Older Patients With Stroke: Patient Selection for Trial Feasibility , Neurology, 102(10): 2024