- Cutaneous atypical lymphocytic infiltrate of skin
- Cutaneous B-cell lymphoma
- Cutaneous lymphoid hyperplasia
- Cutaneous T-cell lymphoma
- Diffuse large B-cell lymphoma
- Lymphomatoid papulosis
- Marginal zone lymphoma
- Mycosis fungoides
- Primary cutaneous CD4+ small or medium T-cell lymphoproliferative disorder
- Primary cutaneous follicle center lymphoma
- Sezary syndrome
Alain H. Rook, MD
Dermatology
Accepting new patients
Sees patients age 18 and up
Penn Dermatology Perelman
Penn Medicine Provider
About me
- Director, Photopheresis Program
- Professor of Dermatology
My education and training
- Medical School: University of Michigan
- Residency: McGill University
- Residency: University of Pennsylvania Health System
- Fellowship: McGill University
- Fellowship: National Institutes of Health
Spoken languages
English
English
Français
French
Reviews
113 reviews
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Insurance accepted
Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.
- Aetna Advantra Cares D-SNP
- Aetna Advantra Credit Value
- Aetna Advantra Eagle HMO
- Aetna Advantra Eagle POS
- Aetna Advantra Premier Plus PPO
- Aetna Advantra Value
- Aetna Advantra Value Plus
- Aetna APCN Plus (Multi-Tier)
- Aetna Better Health Kids (CHIP) - DH Only
- Aetna Flexible Five
- Aetna Freedom Core
- Aetna Gold
- Aetna HMO
- Aetna Philly Prime
- Aetna POS
- Aetna PPO APCN
- Aetna Premier
- Aetna Premier Plus
- Aetna Savings Plus
- Aetna Signature Administrators
- Aetna Student Health Plan PPO
- Aetna Upfront Advantage
- First Health HMO
- First Health POS
- First Health PPO
- Meritain - Aramark (Other)
- Meritain - Aramark (Pennsylvania Premier Medical Plan)
- Americhealth Caritas of PA VIP - LGH Only
- Amerihealth Caritas (Transplant patients only)
- Amerihealth Caritas of PA - LGH Only
- Centivo EPO
- Cigna Healthcare EPO
- Cigna Healthcare HMO
- Cigna Healthcare POS
- Cigna Healthcare PPO
- Claim Watcher (Homestead/ INDECs) Open Access
- Clover Health Choice
- Clover Health Choice Value PPO
- Clover Health Classic HMO
- Clover Health Value
Locations
Penn Medicine hospital privileges
- Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
- Penn Presbyterian Medical Center: On the medical staff, but does not have privileges to treat patients in the hospital.
Qualifications and experience
- Dermatology
- Nephrology, 1980
- Internal Medicine, 1979
- American Academy of Dermatology, National
- American Dermatological Association, National
- American Federation for Medical Research, National
- Canadian Dermatological Association (Honorary), International
- International Cutaneous Lymphoma Society, International
- Pennsylvania Academy of Dermatology, Local
- Society for Investigative Dermatology, National
- Society for Investigative Dermatology, National
- United States Cutaneous Lymphoma Consortium, National
- Recognized annually in Philadelphia Magazine's Top Docs issue from 2004 through 2025
Treatments and conditions
Research
Publications
Weiner DM, Clark AK, Bhansali RS, Pappas-Taffer L, Barta SK, Villasenor-Park J, Haun PL, Vittorio CC, Rook AH, Kim EJ, Samimi SS. Usage and safety of topical tacrolimus in patients with mycosis fungoides , Clin Exp Dermatol.: 2022
Nihal M, Wu J, Stonesifer CJ, Daniels J, Choi J, Geskin L, Rook AH, Wood GS. Epigenetic Regulation of Apoptosis in Cutaneous T-Cell Lymphoma: Implications for Therapy with Methotrexate, Jak Inhibitors, and Resveratrol , J Invest Dermatol. , 142(2): 2022,493-496
Lewis DJ, Rook AH. Combination therapies for mycosis fungoides/Sézary syndrome: biologic rationale and recommendations , Int J Dermatol., 60(9): 2021,e362-e364
Lewis DJ, Haun PL, Samimi SS, Vittorio CC, Villasenor-Park J, Barta SK, Landsburg DJ, Svoboda J, Nasta SD, Schuster SJ, Rook AH, Kim EJ. Brentuximab Vedotin for Relapsed or Refractory Sézary Syndrome , JAMA Dermatol. , 157(3): 2021,317-321
Kim EJ, Kim YH, Rook AH, Lerner A, Duvic M, Reddy S, Robak T, Becker JC Clinically significant responses achieved with romidespsin across disease compartments in patients with cutaneous T-cell lymphoma , Leuk Lymphoma : 2015,1-22
Kim EJ, Kim YH, Rook AH, Lerner A, Duvic M, Reddy S, Robak T, Becker JC, Samtsov A, McCulloch W, Waksman J, Whittaker S. Clinically significant responses achieved with romidepsin across disease compartments in patients with cutaneous T-cell lymphoma. , Leuk Lymphoma, 20: 2015,1-22
Cedeno-Laurent F, Singer Em, Wysocka M, Benoit BM, Vittorio CC, Kim EJ, Yosipovitch G, Rook AH. Improved pruritus correlates with lower levels of IL-31 in CTCL patients under different therapeutic modalities. , Clin Immunol, 158(1): 2015,1-7
Spaccarelli N, Gharavi M, Saboury B, Cheng G, Rook AH, Alavi A. Role of (18)F-fluorodeoxyglucose positron emission tomography imaging in the management of primary cutaneous lymphomas. , Hell J Nucl Med, 17(2): 2014,78-84
Wysocka M, Kossenkov AV, Benoit BM, Troxel AB, Singer E, Schaffer A, Kim B, Dentchev T, Nagata S, Ise T, Showe LC, Rook AH. CD164 and FCRL3 are highly expressed on the CD4+CD26- T-cells in Sezary Syndrome patients. , J Invest Dermatol, 134: 2014,229-36
Samimi S, Chu E, Seykora J, Loren A, Vittorio C, Rook A, Rosenbach M, Kim EJ. Dasatinib-induced leukotrichia in a patient with chronic myelogenous leukemia. , JAMA Dermatol, 149(5): 2013