Penn, CHOP team awarded Breakthrough Prize for blindness gene therapy
Jean Bennett, Albert Maguire, and Kathy High honored for trailblazing work on the first FDA-approved gene therapy for an inherited condition.
A prescription for pharmacy innovation
The pharmacy system of the future is here at Penn Medicine: a powerful union of advanced tech with human expertise, improving patients’ health.
Latest articles
The life-saving cycle of scientific innovation
How discoveries become cures, in a virtuous cycle
Public investments in biomedical research have an outsized effect, driving new scientific insights, economic growth, and ultimately treatments and cures.
How future cures begin as ideas in laboratories
The successes of CAR T research show the importance of the cycle of science—sparking new ideas and clinical trials that give patients better options.
Academia and industry form powerful partnerships for impact
The Penn Medicine Co-Investment program spurs faculty innovation, creates jobs, and helps scale up ideas into large-scale clinical studies.
Breathtaking discoveries that can transform medicine
How DNA folding silences a key gene in Friedreich’s ataxia
Penn research into Friedreich’s ataxia reveals how DNA folding can silence a key gene.
Blood test predicts kidney failure risk to Black Americans
A Penn Medicine study finds that a blood test predicts kidney failure risk to Black Americans years before onset.
Specialized RNA molecules could counter ALS neurodegeneration
Newly discovered molecules bind and restore function to the primary target of ALS in an animal model, pointing toward a new RNA-based therapeutic strategy.
Benchmarks: recent highlights of discovery science
Fighting cancer with CAR T cell immunotherapy
New KIR-CAR T cell therapy shows promise in solid cancers
An early report of a new type of CAR T cell therapy, called KIR-CAR, was shared in a Clinical Trial Plenary session at the AACR Annual Meeting 2026.
The compassionate team behind CAR T cancer breakthroughs
Clinical research professionals’ quiet work with patients and data behind the scenes is vital to moving innovative research forward.
Carl June on the boundless potential of CAR T cell therapy
Carl June, MD, explains how CAR T cell therapy, which has been transformative for blood cancers, holds the potential to help millions more patients.
Leading the way with innovative transplant methods
Bilateral hand transplant at Penn Medicine gives man new hands
Bilateral hand transplant at Penn Medicine gives Swiss man new hands 16 years after childhood amputations.
Families formed and found via uterus transplant celebrate motherhood
Uterus transplant is still a rare procedure—but for the six moms who have had eight babies to date through Penn’s program, it means the world.
Back on her feet and breathing
The Penn Lung Rescue team kept Bri Iacona alive for four months with the most advanced form of life support before she could have a double lung transplant.
Our Nobel Prize-winning mRNA technology
New research seeks an mRNA therapy for heavy menstrual bleeding
Every minute in the U.S., a woman needs a blood transfusion due to her period. Kathleen O’Neill, MD, is working to develop a novel therapy to protect women.
DNA-LNPs: A safer, longer-lasting gene therapy breakthrough
A new DNA delivery method could transform treatment for millions suffering from common chronic diseases like heart disease, diabetes, and cancer.
How Penn Medicine is changing the world with mRNA
Biomedical innovations using mRNA could prevent, treat, or cure numerous diseases. Penn Medicine is advancing its Nobel Prize-winning technology worldwide.
Intercepting cancer before it starts
Volunteering for cancer research: an act of love
The Basser Center for BRCA is running an innovative cancer interception clinical trial that depends on volunteers with deep, personal ties to cancer.
Can we intercept cancer? A new frontier in cancer research
Penn Medicine researchers are at the forefront of new scientific efforts to interrupt the development of cancer at its earliest stages.
New strategy targets pancreatic cancer before it forms
A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors.
Outstanding research leaders at the forefront
Penn and CHOP name founding director for Lurie Autism Institute
Penn Medicine and Children’s Hospital of Philadelphia have appointed Eric M. Morrow, MD, PhD, as the founding director of the Lurie Autism Institute.
Samuel Parry awarded SMFM Lifetime Achievement Award
Samuel Parry, MD, the Franklin Payne Professor of Obstetrics and Gynecology at Penn has been awarded the Society of Maternal Fetal Medicine (SMFM)’s 2026 Lifetime Achievement Award.
Four Penn studies named among nation’s top clinical research advances
Perelman School of Medicine papers win Clinical Research Forum’s 2026 Top 10 Clinical Research Achievement Awards, highlighting the power of federal funding for science.