Jean Bennett, Albert Maguire, and Kathy High honored for trailblazing work on the first FDA-approved gene therapy for an inherited condition.
The pharmacy system of the future is here at Penn Medicine: a powerful union of advanced tech with human expertise, improving patients’ health.
From planting to event planning, the LeadIN program teaches Philly teens about environmental justice and leadership skills.
A newly uncovered genetic variant can leave central vision relatively untouched but causes loss of peripheral and low-light vision.
Dana Sherer shares her perspective on going through a breast cancer diagnosis and treatment as a mom to a newborn and toddler.
Julia Puchtler will lead Penn Medicine’s financial strategy and help shape long-term investments in patient care, research, and education.
The gift establishes the Middleman Center and Middleman Fund to advance promising discoveries and speed new treatments to patients.
Public investments in biomedical research have an outsized effect, driving new scientific insights, economic growth, and ultimately treatments and cures.
The successes of CAR T research show the importance of the cycle of science—sparking new ideas and clinical trials that give patients better options.
The Penn Medicine Co-Investment program spurs faculty innovation, creates jobs, and helps scale up ideas into large-scale clinical studies.
Penn research into Friedreich’s ataxia reveals how DNA folding can silence a key gene.
A Penn Medicine study finds that a blood test predicts kidney failure risk to Black Americans years before onset.
Newly discovered molecules bind and restore function to the primary target of ALS in an animal model, pointing toward a new RNA-based therapeutic strategy.
A new DNA-editing technology that uses a small drug-like molecule enables the precise identification and modification of genetic vulnerabilities in cancer, which allows researchers to turn on high-efficiency gene editing at a chosen time in animal models of cancer. — April 15, 2026
Higher estrogen levels in the brain’s hippocampus may increase women’s vulnerability to PTSD after stressful events because the hormones un-silence memory-related genes through “opening” tightly coiled DNA, which affects memory. — April 15, 2026
Within a single day, a host of extremely potent and durable CAR T cells effective against both blood cancers and solid tumors could be generated from living patients’ own cells. This process could potentially expand access and reduce the cost of CAR T therapy. — April 16, 2026
An early report of a new type of CAR T cell therapy, called KIR-CAR, was shared in a Clinical Trial Plenary session at the AACR Annual Meeting 2026.
Clinical research professionals’ quiet work with patients and data behind the scenes is vital to moving innovative research forward.
Carl June, MD, explains how CAR T cell therapy, which has been transformative for blood cancers, holds the potential to help millions more patients.
Bilateral hand transplant at Penn Medicine gives Swiss man new hands 16 years after childhood amputations.
Uterus transplant is still a rare procedure—but for the six moms who have had eight babies to date through Penn’s program, it means the world.
The Penn Lung Rescue team kept Bri Iacona alive for four months with the most advanced form of life support before she could have a double lung transplant.
Every minute in the U.S., a woman needs a blood transfusion due to her period. Kathleen O’Neill, MD, is working to develop a novel therapy to protect women.
A new DNA delivery method could transform treatment for millions suffering from common chronic diseases like heart disease, diabetes, and cancer.
Biomedical innovations using mRNA could prevent, treat, or cure numerous diseases. Penn Medicine is advancing its Nobel Prize-winning technology worldwide.
The Basser Center for BRCA is running an innovative cancer interception clinical trial that depends on volunteers with deep, personal ties to cancer.
Penn Medicine researchers are at the forefront of new scientific efforts to interrupt the development of cancer at its earliest stages.
A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors.
Penn Medicine and Children’s Hospital of Philadelphia have appointed Eric M. Morrow, MD, PhD, as the founding director of the Lurie Autism Institute.
Samuel Parry, MD, the Franklin Payne Professor of Obstetrics and Gynecology at Penn has been awarded the Society of Maternal Fetal Medicine (SMFM)’s 2026 Lifetime Achievement Award.
Perelman School of Medicine papers win Clinical Research Forum’s 2026 Top 10 Clinical Research Achievement Awards, highlighting the power of federal funding for science.
