From the lab bench to the cloud, Penn Medicine is at the forefront of biomedical discovery—translating research into real-world impact. Explore the latest breakthroughs.
A $50 million gift from the Lurie family to Children’s Hospital of Philadelphia and Penn Medicine will launch the Lurie Autism Institute to drive autism research.
In a historic medical breakthrough, a child with a rare genetic disorder has been successfully treated with a customized CRISPR gene editing therapy.
Nancy A. Speck, PhD, has been named the 2025 recipient of the E. Donnall Thomas Lecture and Prize from the American Society of Hematology (ASH).
Getting Luka Krizanac new hands took 16 years, a connection between a surgeon and his mentor, and surgeries on two continents.
Tailored feedback to surgeons dramatically cuts excessive opioid prescriptions for common surgeries, aligning them with evidence-based guidelines without affecting patient pain control.
For five years, Penn Medicine’s Social Needs Response Team has connected patients to vital support foundational to good health.
Clinical research professionals’ quiet work with patients and data behind the scenes is vital to moving innovative research forward.
A dual-target CAR T cell therapy approach shows promise for slowing tumor growth in a notoriously aggressive and fast-growing brain cancer.
Carl June, MD, explains how CAR T cell therapy, which has been transformative for blood cancers, holds the potential to help millions more patients.
Bilateral hand transplant at Penn Medicine gives Swiss man new hands 16 years after childhood amputations
Uterus transplant is still a rare procedure—but for the six moms who have had eight babies to date through Penn’s program, it means the world.
In a proof of concept for a future bridge to transplant, researchers circulated a deceased donor’s blood through a genetically engineered pig liver.
Penn researchers designed an organ-specific mRNA and lipid nanoparticle therapy which could lead to new targeted treatments for damaged organs.
Could the mRNA technology behind COVID vaccines be used to tamp down the immune system for celiac and other autoimmune diseases?
Biomedical innovations using mRNA could prevent, treat, or cure numerous diseases. Penn Medicine is advancing its Nobel Prize-winning technology worldwide.
The Basser Center for BRCA is running an innovative cancer interception clinical trial that depends on volunteers with deep, personal ties to cancer.
Penn Medicine researchers are at the forefront of new scientific efforts to interrupt the development of cancer at its earliest stages.
The gift from Penn alumni Mindy and Jon Gray establishes the Basser Cancer Interception Institute to stop hereditary cancers at the earliest stages.
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