News Releases

The new Penn Achilles Tendinopathy Center of Research Translation seeks to build insights that lead to better treatment of Achilles tendon injuries.

One protein, Piezo1, is key to marshalling muscle stem cells’ unique shapes and response to injuries, but it is in low supply in those with Duchenne muscular dystrophy, according to a team at the Perelman School of Medicine at the University of Pennsylvania.

The Perelman School of Medicine at the University of Pennsylvania came in at number one for the most funds awarded to a United States orthopaedic surgery department by the National Institutes of Health (NIH) in 2021.

When patients’ hip or knee replacements were delayed in response to COVID-19 surges, chatbots delivering encouraging messages not only benefited the mental health of patients – they also experienced boosts to their physical health, too.

Impaired and inefficient muscle tissue regeneration appears to open the door for unwanted bone to form in areas where new muscle should occur after injuries. This discovery opens up the possibility of pursuing new therapies for fibrodysplasia ossificans progressiva and was published in NPJ Regenerative Medicine.

Long-time funding for work at the Penn Center for Musculoskeletal Disorders has been renewed for another five years by the National Institute of Arthritis, Musculoskeletal, and Skin Diseases (NIAMS) of the National Institutes of Health (NIH). The additional $4 million in funding will continue the center’s investigations into all types of musculoskeletal tissue injury and repair.

An overactive genetic pathway in muscle stem cells was found to shorten the ends of chromosomes, called telomeres, resulting in DNA damage that impedes the normal healing response, according to a new study by researchers in the Perelman School of Medicine at the University of Pennsylvania.