Hospital of the University of Pennsylvania

Here are driving directions and parking information at the Hospital of the University of Pennsylvania.

The Hospital of the University of Pennsylvania is located at 34th and Spruce Streets. The address is 3400 Civic Center Boulevard, Philadelphia, PA 19104. The main entrance of the hospital and valet parking are located on 34th Street.

Driving Directions

Garage parking is easily accessible from the University Avenue exit (346B) off of I-76. See directions below.

From Northeastern Areas

From I-95 South, take the Vine Street/Center City Exit, stay left to 676 West (Vine Street Express-way). Follow 676 West to the I-76 East Exit 1, International Airport. Follow I-76 East (Schuylkill Expressway) to Exit 346B, University Avenue. Continue on University Avenue, and then turn right onto Civic Center Boulevard. Turn right onto Health Sciences Drive. Follow GARAGE DIRECTIONS below.

From the West & Montgomery County

Take the Pennsylvania Turnpike to Exit 326, Valley Forge. Take I-76 East (Schuylkill Expressway) approximately 17 miles to Exit 346B, University Avenue. Continue on University Avenue, and then turn right onto Civic Center Boulevard. Turn right onto Health Sciences Drive. Follow GARAGE DIRECTIONS below.

From the North

Take I-476 (Northeast Extension) South to Exit 20, Mid-County. Pay the toll and continue south on I-476 to Exit 16A, I-76 East. Follow I-76 East (Schuylkill Expressway) approximately 17 miles to Exit 346B, University Avenue. Continue on University Avenue, and then turn right onto Civic Center Boulevard. Turn right onto Health Sciences Drive. Follow GARAGE DIRECTIONS below.

From the South/Philadelphia International Airport

Take I-95 North to Exit 13, PA-291 toward I-76 West/Valley Forge (Schuylkill Expressway). Merge right. Cross Girard Point Bridge and turn left at light on 26th Street. Merge on I-76 West to Exit 346B, University Avenue. Continue on University Avenue, and then turn right onto Civic Center Boulevard. Turn right onto Health Sciences Drive. Follow GARAGE DIRECTIONS below.

From New Jersey

Take I-295 to the Walt Whitman Bridge. Follow signs for I-76 West (Schuylkill Expressway) and take Exit 346B, University Avenue. Continue on University Avenue, and then turn right onto Civic Center Boulevard. Turn right onto Health Sciences Drive. Follow GARAGE DIRECTIONS below.

Hospital of the University of Pennsylvania campus map

Download campus map with traffic patterns, driving directions and parking information (PDF)

From Philadelphia International Airport

  • Driving: All major car rental companies are located at the airport.
  • Airport Train: The train leaves every half hour at 10 minutes and 40 minutes past the hour, and it arrives at University City Station on the HUP campus. The train costs approximately $5 and takes 20 minutes.
  • Taxi: A metered cab from the airport costs approximately $20 and the ride takes approximately 20 minutes.

Garage Directions and Rates

Parking garages are available at the Perelman Center for Advanced Medicine and the 3600 Civic Center Boulevard garage. 

A free shuttle service will be available to the Hospital of the University of Pennsylvania and the Perelman Center for Advanced Medicine on a continuous loop from the 3600 Civic Center Boulevard garage Level 2 transportation center.

HUP Security also provides walking escorts to any employee, patient or visitor who requests an escort to parking garages, lots and streets surrounding the hospital perimeter. Escorts are always available — timing depends on security officer availability. Please call 215-662-2677 to request a walking escort.

Self-Parking at the Perelman Center for Advanced Medicine Garage

Directions from the University Avenue exit (346B) off of I-76

From Health Sciences Drive, continue on Health Sciences Drive for approximately 600 yards and the entrance to the garage is on your left after East Service Drive. This garage services both the Perelman Center for Advanced Medicine and the Hospital of the University of Pennsylvania.

Directions from the South Street exit (346A) off of I-76

Follow I-76 to Exit 346A, South Street (left exit), and head west on South Street. Continue straight onto Spuce Street. From Spruce Street, turn onto 34th Street which becomes Civic Center Boulevard. Turn left on East Service Drive and then turn left onto Health Sciences Drive and into the Perelman Center garage.

  • Hours
    • Open 24/7
  • Rates
    • Up to 3 hours: $7 (Patients/Family), $13 (Non-Patients)
    • 3 to 7 hours: $10 (Patients/Family), $18 (Non-Patients)
    • 7 to 24 hours: $11 (Patients/Family), $20 (Non-Patients)

Patients and guests 62 years and older are eligible for a senior discount. ($1 off, up to 3 hrs.; $2 off, 3 hrs. or over)

Self-Parking at the 3600 Civic Center Boulevard Parking Garage

Directions from the University Avenue exit (346B) off of I-76

From Health Sciences Drive, turn left on West Service Drive and then left into the garage. This garage services both the Perelman Center for Advanced Medicine and the Hospital of the University of Pennsylvania.

Directions from the South Street exit (346A) off of I-76

Follow I-76 to Exit 346A, South Street (left exit), and head west on South Street. Continue straight onto Spuce Street. From Spruce Street, turn onto 34th Street which becomes Civic Center Boulevard. Continue on Civic Center Boulevard and make a left onto West Service Drive. The entrance to the garage is on the right.

  • Hours
    • Open Monday at 5 am and remains open through Friday at midnight
    • Saturday and Sunday closed.
  • Rates
    • Patient daily rate is $5.
    • Non-patient daily rate is $20.

Valet Directions and Rates

Valet parking is easily accessible from the South Street exit (346A) off of I-76. See directions below.

Hospital of the University of Pennsylvania, Main Entrance

Follow I-76 to Exit 346A, South Street (left exit), and head west on South Street. Turn left onto 34th Street. Enter the main entrance for the Hospital of the University of Pennsylvania, which is on the right.

Hours

  • Monday through Friday: 5:30 am to 10 pm.
  • Saturday and Sunday: 10 am to 9 pm.

Perelman Center for Advanced Medicine, Main Entrance

Follow I-76 to Exit 346A, South Street (left exit), and head west on South Street. Turn left on 34th Street. Continue past the Hospital of the University of Pennsylvania, which will be on the right. Turn left into the main entrance for The Perelman Center for Advanced Medicine.

Hours

  • Monday through Friday: 5:30 am to 10 pm
  • Saturday and Sunday: 10 am to 9 pm

Rates

  • Up to 3 hours: $10 (Patients/Family), $15 (Non-Patients)
  • 3 to 7 hours: $13 (Patients/Family), $19 (Non-Patients)
  • 7 to 24 hours: $14 (Patients/Family), $21 (Non-Patients)

Servicing both the Perelman Center for Advanced Medicine and the Hospital of the University of Pennsylvania.

Patients and guests 62 years and older are eligible for a senior discount. ($1 off, up to 3 hrs.; $2 off, 3 hrs. or over)

Long-Term Parking

For patients requiring an extended hospitalization, parking passes are available to family members at a discounted rate:

  • 15 Day Pass: Allows unlimited in/out parking in the Perelman Center garage, or the 3600 Civic Center Boulevard garage for 15 consecutive days. (Cost: $80)
  • 7 Day Pass: Allows unlimited in/out parking in the Perelman Center garage, or the 3600 Civic Center Boulevard garage for seven consecutive days. (Cost: $45)
  • There is no reimbursement for days not used or lost/stolen cards.
  • Long-term parking passes can be purchased at the Cashier's Booth located on the ground floor of the Perelman Center.

Public Transportation

Amtrak

215-824-1600 | www.amtrak.com

  • Northeast corridor Amtrak trains stop at 30th Street Station. See SEPTA Regional Rail Lines or SEPTA City Transit for information on travelling to the hospital from 30th Street Station. Taxi service also is available at 30th Street Station.

SEPTA

215-580-7800 | www.septa.org

  • Regional Rail Lines
    • The Airport, Marcus Hook-Wilmington, Media-Elwyn and most Glenside-Jenkintown, Warminster and West Trenton trains provide direct service to the University City Station on the Medical Center campus.
    • From other Regional Rail lines, transfer free to the Airport, Marcus Hook-Wilmington, Media-Elwyn and most Glenside-Jenkintown, Warminster and West Trenton trains at 30th Street or Jefferson Station (formerly Market East station). Your train ticket is your transfer.
  • SEPTA City Trains and Trolleys
    • The SEPTA Market/Frankford Blue Line (the elevated train/subway) stops at 34th and Market Sts. A 10-minute walk south on 34th Street or a 5-minute ride on the LUCY shuttle takes you to the Hospital.
    • All SEPTA Subway/Surface Green Line trolleys except the Number 10 stop at 37th and Spruce streets, one block from the Rhoads entrance to the Hospital on 36th Street south of Spruce Street. If you take the Number 10 trolley, travel to 36th and Sansom streets. Walk four blocks south on 36th Street to the Rhoads entrance of the Hospital.
  • LUCY® (Loop Through University City)
    This SEPTA-run shuttle bus is free to students of the University of Pennsylvania and employees of University of Pennsylvania, Penn Medicine, University City Science Center, and Children's Hospital of Philadelphia. All others can ride with Trans or TrailPass, transfers, or $2.25 bus fare. LUCY® has a wheelchair lift and two wheelchair tie-downs per bus. - See schedules and more at: www.universitycity.org/lucy.
    • The LUCY® shuttle runs every 12 to 35 minutes from 6:10am to 7:00pm, Monday through Friday except major holidays (New Year's Day, Memorial Day, Independence Day, Labor Day, Thanksgiving, and Christmas Day).

New Jersey PATCO Trains

215-922-4600 | www.ridepatco.org

  • Take the PATCO line to 8th and Market streets. Follow the underground concourse to the SEPTA Jefferson Station (formerly Market East station). From there, the R1 Airport, R2 Marcus Hook-Wilmington, and R3 Media-Elwyn Regional Rail lines provide direct service to the University City Station on the Medical Center campus.
  • Or you may transfer from PATCO at 8th and Market streets to the SEPTA Market/Frankford Blue Line (the elevated train/subway). Take the westbound train to 34th and Market streets. A 10-minute walk south on 34th Street takes you to the Hospital.

Greyhound Bus Lines

800-231-2222 | www.greyhound.com

  • From the Greyhound Bus Station at 10th and Filbert streets, walk to the Jefferson Station (formerly Market East station) at 11th and Market streets. From there, take the R1 Airport, R2 Marcus Hook-Wilmington, or R3 Media-Elwyn Regional Rail line to the University City Station on the Medical Center Campus. A taxi ride from the Greyhound Bus station costs about $12.
Share This Page: