Subacute thyroiditis is an immune reaction of the thyroid gland that often follows an upper respiratory infection.
The thyroid gland is located in the neck, just above where your collarbones meet in the middle.
De Quervain's thyroiditis; Subacute nonsuppurative thyroiditis; Giant cell thyroiditis; Subacute granulomatous thyroiditis; Hyperthyroidism - subacute thyroiditis
Subacute thyroiditis is a rare condition. It is thought to be caused by a viral infection. The condition often occurs after a viral infection of the ear, sinus, or throat, such as mumps, the flu, or a common cold.
Subacute thyroiditis occurs most often in middle-aged women with symptoms of a viral upper respiratory tract infection in the past month.
The most obvious symptom of subacute thyroiditis is pain in the neck caused by a swollen and inflamed thyroid gland. Sometimes, the pain can spread (radiate) to the jaw or ears. The thyroid gland may be painful and swollen for weeks or, in rare cases, months.
Other symptoms include:
- Tenderness when gentle pressure is applied to the thyroid gland
- Difficulty swallowing, hoarseness
- Fatigue, feeling weak
The inflamed thyroid gland may release too much thyroid hormone, causing symptoms of hyperthyroidism, including:
- More frequent bowel movements
- Hair loss
- Heat intolerance
- Irregular menstrual periods in women
- Mood changes
- Nervousness, tremor
- Weight loss, but with increased appetite
As the thyroid gland heals, it may release too little hormone, causing symptoms of hypothyroidism, including:
- Cold intolerance
- Weight gain
- Dry skin
- Mood changes
Thyroid gland function often returns to normal. But in rare cases, hypothyroidism may be permanent.
Exams and Tests
Laboratory tests that may be done include:
- Thyroid stimulating hormone (TSH) level
- T4 (thyroid hormone, thyroxine) and T3 level
- Radioactive iodine uptake
- Erythrocyte sedimentation rate (ESR)
In some cases, a thyroid biopsy may be done.
The goal of treatment is to reduce pain and treat hyperthyroidism, if it occurs. Drugs such as aspirin or ibuprofen are used to control pain in mild cases.
More serious cases may need short-term treatment with drugs that reduce swelling, such as prednisone. Symptoms of an overactive thyroid are treated with a class of drugs called beta-blockers.
The condition should improve on its own. But the illness may last for months. Long-term or severe complications do not often occur.
When to Contact a Medical Professional
Call your health care provider if:
Vaccines that prevent viral infections such as the flu may help prevent subacute thyroiditis. Other causes may not be preventable.
Davies TF, Laurberg P, Bahn RS. Hyperthyroid disorders. In: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Textbook of Endocrinology. 13th ed. Philadelphia, PA: Elsevier; 2016:chap 12.
Guimaraes VC. Subacute and Riedel's thyroiditis. In: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 87.
- Last reviewed on 2/3/2016
- Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is the first of its kind, requiring compliance with 53 standards of quality and accountability, verified by independent audit. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial process. A.D.A.M. is also a founding member of Hi-Ethics (www.hiethics.com) and subscribes to the principles of the Health on the Net Foundation (www.hon.ch).
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2002 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.