Myopathies

Acquired myopathies are a diverse group of disorders in which the primary symptom is muscle weakness. Muscle dysfunction most commonly produces progressive weakness of the arms and legs. There are many causes of myopathy, including those due to inflammation in the muscles themselves (polymyositis, dermatomyositis and inclusion body myositis). Myopathies can also be caused by various medical diseases and even by certain drugs, such as those that are used to control elevated blood cholesterol.

Adults with acquired myopathies (polymyositis, dermatomyositis and inclusion body myositis) are cared for at the MDA Clinic at the Hospital of the University of Pennsylvania. The MDA maintains a network of 200 specialized clinics across the United States. Once a diagnosis is made, appropriate treatment will be implemented, including adjustment of immunosuppressant medications if needed. Physical therapy is generally prescribed and therapeutic exercise plays a large role in management of the muscle weakness in most patients.