Neurosurgery
Expert surgery, powered by research
Penn Medicine neurosurgeons perform thousands of procedures each year involving the brain, spinal cord, and nervous system. Our skilled surgeons apply the latest research to develop advanced surgical techniques for a wide range of neurological disorders, including spinal injuries, brain tumors, strokes, and epilepsy.
Conditions we treat
Cavernous Malformation Center
As one of the nation's few centers dedicated to the diagnosis and treatment of cavernous malformations, our skilled surgeons see a high volume of patients each year. Using the latest diagnostic tools, each patient receives a customized treatment plan tailored to their exact needs.
Our doctors
Our providers work with you to plan and deliver exceptional treatment and personalized care.
Locations
Our hospitals, multispecialty medical centers, pharmacies, labs and more offer outstanding, personalized care for patients all across the region.
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Penn Medicine at the 2025 ASCO Annual Meeting
Penn Medicine researchers will present data on the latest advances in cancer science and medicine at the 2025 ASCO Annual Meeting.
Brain tumor organoids model response to CAR T cell treatment
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Patient stories
Actress returns to the stage after finding seizure relief
“Even though it had only been five years, epilepsy had taken away [the] career that meant so much to me.”
Real-time tumor assessment brings relief
“Hearing my results right away and walking away from an appointment with a game plan lets me enjoy my life between scans,” said Lynn Oxenberg.
Epilepsy surgery gave Ann Rossi a new lease on life
“I was lucky if I could hold on to a thought for more than a few seconds. Now I’m retaining information for a couple of weeks. I’m having a hard time describing this experience as anything but life-changing.”
A tiny laser gave one patient relief from lifelong seizures.
"Minimally invasive surgery with lasers allows us access to areas [of the brain] that were traditionally not accessible in many patients."
Before launching a new CNN show, journalist Kasie Hunt had a brain tumor removed
“There’s nowhere in the world I would rather have this done than at Penn.”
Emergency protocol delivers fast, lifesaving stroke care
Dick recalled a paramedic asking him questions, but he was unable to respond. The moments that followed were largely a blur.
A remarkable recovery after a ruptured brain aneurysm
I immediately knew something was wrong. I get migraines. This was nothing like a migraine.
Rediscovering joy after treatment for a pituitary condition
I felt like a completely different person… that referral saved me.
An unexpected diagnosis and a surreal surgery
“No one ever wants to go through this, but having this support system in place for my own journey has helped me to feel like I’m in the best hands at every turn.”
Life-saving neurology expertise when you need it most
“We had recently relocated to Newtown Square from outside New York City, to be closer to family. Had we not been near Philadelphia, I wouldn’t have come to Penn Medicine, and wouldn’t have been treated by Drs. Orthmann-Murphy and Yoshor. I might not have survived,” Shannon Cook said. “I have this overwhelming feeling of thank God that we’re here.”