What is a pericardiectomy?

A pericardiectomy is a surgical procedure to remove the pericardium, the membrane surrounding the heart. It is used to treat constrictive pericarditis, a cardiac condition in which the pericardium becomes stiff and inflamed. This prevents the heart from fully expanding when it beats, subsequently causing the blood to become backed up behind the heart, resulting in heart failure symptoms.

By removing all or a large part of the pericardium through this surgery, the heart can fully fill with blood again. While pericardiectomy enables the resumption of normal blood flow to and from the heart, it does not resolve the cause of the initial inflammation.

The function of the pericardium

The pericardium, also called the pericardial sac, serves an important role in cardiac and pericardial function. As a fluid-filled fibrous sac that surrounds the heart, the pericardium acts as a protective layer to the heart and the connecting larger vessels. It also performs as a lubricant to decrease friction between the heart and neighboring structures.

When the pericardium becomes inflamed and stiffened during pericarditis, the lubricating function is no longer able to be performed and the abnormal structure puts the heart at risk.

Despite the vital role that it serves, removing the pericardium will not impact future heart health if the rest of the surrounding structures (lungs and diaphragm) are unharmed and healthy.

Is pericardiectomy an open-heart surgery?

Pericardiectomy is typically performed as an open-heart surgical procedure. Using a minimally invasive approach limits the amount of pericardium that can be removed. Creating a larger incision with open-heart surgery allows cardiac surgeons to have access to the entire pericardium around your heart for removal, rather than performing the lesser preferred partial pericardiectomy.

Why might a pericardiectomy be needed?

Someone with chronic constrictive pericarditis, as opposed to a singular occurrence of pericarditis, is an optimal candidate for pericardiectomy surgery. Constrictive pericarditis involves a more permanent thickening and scarring, which may benefit from a surgical intervention, whereas mild pericarditis may go away on its own.

Pericardiectomy may also be needed for:

  • Recurring pericarditis, regardless of severity
  • Pericardial effusion (buildup of fluid in the pericardium)
  • Pericarditis that is not responding to or has complications from anti-inflammatory medication

What happens during a pericardiectomy?

Pericardiectomy is performed under general anesthesia, so your cardiac surgeon works closely with a cardiac anesthesiologist to ensure you’re safe and comfortable. Next, they:

  • Make an incision through the breastbone to access the heart. You will be connected to a heart-lung machine, which takes over the work of your heart so it is still while the surgeon operates.
  • Cut away all or part of the pericardium, allowing it to move and expand more freely.
  • Perform other procedures. If you need other heart repairs, your surgeon can often perform them during the same operation. You benefit by undergoing general anesthesia only once.
  • Close the incision

A pericardiectomy typically takes two to three hours to complete.

Pericardiectomy recovery and cardiac rehabilitation

Immediately after surgery, your care team will move you to a recovery unit for close observation while you wake up. You will then move to the intensive care unit (ICU) where you will be cared for by a team of cardiac specialists. Patients are usually moved to a regular nursing floor within 24 hours with close monitoring until discharge.

To help you quickly return to an active lifestyle after surgery, you may benefit from cardiac rehab when you leave the hospital. Our rehabilitation specialists provide gentle exercises, nutrition guidance and support in an outpatient facility.

Recovery after a pericardiectomy takes between six to eight weeks on average.

Benefits and risks of pericardium removal

Pericardiectomy offers several advantages as a treatment for constrictive pericarditis. Removing the inflamed and stiff pericardium eliminates the ability for any constriction and the symptoms it causes. Without a pericardium, patients often experience complete relief or only mild symptoms for several years post-surgery. The possibility of a complete cure for your constrictive pericarditis is much greater with surgery than with management through medication.

Most complications of the procedure are associated with certain risk factors. These include previous heart surgeries, existing severe cardiac and medical conditions or a history of radiation therapy (a possible cause of constrictive pericarditis). Complications that may occur with open-heart pericardiectomy surgery include bleeding, atrial fibrillation and infection.

Surgical care for pericarditis: Why choose Penn Medicine

  • Surgical expertise: Our surgeons perform more than 3,000 procedures each year. Our high volumes translate into greater surgical expertise and better outcomes for you.
  • Personalized treatment options: Though pericardiectomy is traditionally an open-heart procedure, Penn surgeons take a minimally-invasive approach whenever possible to improve healing and recovery time.
  • Care close to home: Penn cardiac surgeons see patients at satellite locations across the community allowing convenient consultations, second opinions and pre- and post- operative care close to home.

Related specialties

Diverse team of doctors having a discussion

Our doctors

Our providers work with you to plan and deliver exceptional treatment and personalized care.

Panoramic shot of Penn Medicine's downtown campus

Locations

Our hospitals, multispecialty medical centers, pharmacies, labs and more offer outstanding, personalized care for patients all across the region.

Patient stories

The road to recovery begins at home

Penn Medicine’s SNF at Home pilot program offers a seamless transition from the hospital to home with extra support to recover in familiar surroundings.

Finding triple-negative breast cancer at 33, she chose ‘Team Penn’

Shocked to learn she had stage III breast cancer, Kate Korson knew just where to go. She flew home to Penn Medicine, where a clinical trial saved her life.

Bringing the hospital home

With Penn Medicine Advanced Home Health, even patients facing a potentially serious medical issue can receive care safely at home.

A journey from battlefield to beating cancer

Andrew Camponelli was a young Army helicopter pilot in Kuwait when he was diagnosed with stage 3 melanoma.

70-year-old bench press competitor tackles rare cancer

While receiving treatment at Penn for a rare cancer, bench press competitor Howard Aaron continued to make fitness an essential part of his life.

Patient puts national spotlight on cancer clinical trials

As Kate Korson recently shared on Good Morning America, both she and her mother participated in clinical trials at Abramson Cancer Center.

How pickleball (and Penn Medicine) saved one patient’s life

With teamwork and determination, specialists at Penn Medicine solved Ronnie Recchia’s life-threatening medical mystery and got him back in the game.

A grateful patient pays it forward to treat uterine cancers

Dalia Jakas credits her doctor with curing her uterine cancer without harming her quality of life. Now, she’s paying it forward for future patients.

Epilepsy surgery gives patient a new lease on life

Minimally invasive laser interstitial thermal therapy (LITT) surgery reduced the epilepsy symptoms a patient had experienced for more than 30 years.

A cancer dietitian, a survivor herself, keeps patients moving

Breast cancer treatments can upend a fitness routine. Cancer dietitian Dorris Piccinin, a survivor herself, is inspiring patients to keep at it.

Schedule an appointment

We can help you schedule an appointment or you can search our directory of specialists.