Heart failure treatment

Medications that treat heart failure

The American College of Cardiology’s latest guidance indicates that people with heart failure should take the highest tolerated doses of heart failure medications. Penn is one of just a few programs with the expertise for this high level of medication management.

At Penn, we have extensive experience with heart failure medications and how to use them most effectively. If you experience side effects, we know how to manage those too. Our goal is to keep you on the type and amount of medication that gives you the best results.

Heart failure treatment often includes a medication that relaxes blood vessels. The goal is to reduce the heart’s workload. Those medicines include:

  • Angiotensin-converting enzyme (ACE) inhibitors
  • Angiotensin II receptor blockers (ARB)
  • Angiotensin receptor neprilysin inhibitors (ARNI)
  • Vasodilators

Sometimes treating heart failure also includes treating conditions that cause it, such as high blood pressure or diabetes. Depending on other causes and symptoms of heart failure, your treatment plan might also include:

  • Beta or alpha blockers, which block certain signals and hormones that raise heart rate
  • Aldosterone antagonists, which block an artery-tightening hormone
  • Anticoagulants (blood thinners) to prevent blood clots
  • Cholesterol-lowering drugs, which lower the chance of heart attack
  • Diuretics (water pills), which help the body get rid of extra fluids and sodium, making it easier for the heart to pump
  • SGLT-2 inhibitors, the most recent class of medications to show improvement in heart failure

Carefully monitoring health and progress on heart medications

Medical management of heart failure is an ongoing process. To make sure your treatment stays effective with minimal side effects and complications, we carefully follow your progress.

Our specially trained heart failure nurses call you regularly to make sure you’re taking your medications and ask about side effects. You’ll have regular bloodwork to monitor kidney function, cholesterol levels, and potassium levels.

This close follow-up allows us to change your medications or dosages quickly and get you the best results.

Types of procedures and surgeries for heart failure

If the cause of your heart failure requires surgery, you’re in good hands with the experts at Penn Heart Failure Program. We offer leading-edge procedures for all types and causes of heart failure.

Treating heart failure: The Penn Medicine difference

Penn is a leader in procedures to repair both common and rare causes of heart failure, with outcomes that exceed national averages. If you need a procedure to manage heart failure, you’re in the best hands. When you choose us, you’ll find:

  • Nationally recognized specialists: Our programs in ablation, transcatheter interventions, bypass surgery, heart transplantation and other cardiac procedures and surgeries are among the best in the nation.
  • Expertise for routine and complex cases: Our specialists treat thousands of people with heart failure each year. This high volume gives us vast experience with even the toughest cases. We can often help patients who have had unsuccessful cardiac treatments or are considered too high-risk elsewhere.
  • Special care for patients with chronic illness: The Heart Failure Program includes palliative care specialists who help patients and families handle the challenges of chronic illness and manage symptoms. They’re here for you before and after heart failure surgery.
  • Close collaboration with your local doctor: Most heart failure surgery patients come to us through referrals from their primary care physicians or cardiologists. We work closely with your regular doctors before, during and after surgery. Once you leave the hospital, your local doctor can manage your care. If you’d like to stay in our care, we can arrange that as well — it’s your choice.
  • Multidisciplinary network: As an academic medical center, Penn’s network includes surgeons, electrophysiologists and interventional cardiologists. They treat every type of cardiac problem, no matter how complex. We collaborate for seamless, individualized care.
  • Clinical trials: As an academic medical center, we are always involved in clinical trials testing new surgical approaches and devices for heart failure. Our research gives our patients access to cutting-edge options that are not available everywhere else.

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