Liver disease care
Specialized liver care focused on you
The liver is the largest organ in the digestive system and carries out more than 100 essential tasks. Its complexity makes it vulnerable to many conditions. Liver problems may be inherited, caused by infections, autoimmune in nature, or triggered by environmental factors. Whether you’re experiencing liver disease in early or advanced stages, experts at Penn Medicine combine advanced diagnostics with innovative therapies to address all types of liver disease.
Our clinicians focus on understanding the complexities of various liver conditions so they can bring the most advanced treatment options to you. Through a multidisciplinary approach to care, our gastroenterology and transplant surgery teams, along with radiology, pathology, and other departments, work together to provide a seamless experience for people with liver disease.
- Liver Tumor Clinic: The Liver Tumor Clinic provides rapid access to multidisciplinary cancer management, facilitating evaluation for liver transplantation, resection, regional interventions, systemic therapy, and combinations thereof, personalized for each patient’s individual needs.
- Ascites Clinic: Our specialized Ascites Clinic offers comprehensive treatment options for patients with refractory ascites, including access to an innovative device that automatically pumps fluid from the abdominal cavity into the bladder.
- iLEARN Clinic: The iLEARN Clinic provides multidisciplinary management of alcohol-related liver disease, with a goal of improving liver transplantation opportunities and outcomes.
Conditions we treat
Advanced endoscopy for early detection and minimally invasive GI care
Our gastroenterologists provide advanced endoscopy to diagnose and treat many gastrointestinal disorders. We use the latest technology to view the digestive tract, find problems early, and provide minimally invasive care for a quicker recovery.
Pioneering treatments for all forms of liver disease
From early-stage conditions to advanced illness, Penn Medicine provides comprehensive care for all forms of liver disease. Our team includes cirrhosis specialists and other liver experts who offer advanced evaluation, treatment, and management of complex liver conditions. Those who require more advanced interventions also have direct access to the Penn Transplant Institute, one of the nation’s leading centers for liver transplantation.
Unmatched experience in hepatobiliary and pancreas surgery
When surgery is needed, our hepatobiliary surgeons have the experience you need to treat your liver, pancreatic, gallbladder, or bile duct condition with precision. We see the highest patient volumes in the region and are often a destination for hard-to-treat cases.
Specialty clinics for advanced liver care
Penn Medicine offers several specialty clinics designed to support people with complex liver conditions. These programs bring together experts from multiple disciplines, provide coordinated care in one place, and offer access to advanced treatments, innovative devices, and ongoing support.
The Liver Tumor Clinic provides comprehensive evaluation and treatment for benign and malignant liver tumors. You receive care from a team of liver specialists, including hepatologists, liver and biliary surgeons, interventional radiologists, medical oncologists, and radiation oncologists. These experts review cases together and create individualized treatment plans.
Care may include surgery (resection), ablation, liver-directed therapies, systemic therapy, or referral for liver transplant when appropriate. This team-based model, supported by high-volume liver surgery and interventional expertise, helps manage complex or previously “inoperable” cases and expands access to curative options when possible.
The Comprehensive Ascites Clinic supports people with cirrhosis who have difficult-to-manage (refractory) ascites. The clinic brings hepatology, interventional radiology, nephrology, nutrition, and palliative care together in one coordinated setting.
Patients may receive treatments such as large-volume paracentesis, diuretic adjustment, TIPS evaluation, and dietary counseling. The clinic also provides access to innovative devices, such as an automatic pump that moves fluid from the abdomen to the bladder, to improve comfort and reduce repeat hospital or emergency visits. The goal is to improve quality of life and deliver consistent, evidence-based care for those with advanced liver disease.
iLEARN is a co-located, multidisciplinary clinic for people with alcohol-associated liver disease who are being evaluated for liver transplant. Hepatologists, psychiatrists, social workers, and addiction counselors work together to provide seamless, long-term support before and after transplant.
The clinic focuses on helping patients stabilize their health, navigate the transplant process, and build the strongest foundation for long-term recovery and post-transplant success.
Our doctors
Our providers work with you to plan and deliver exceptional treatment and personalized care.
Locations
Our hospitals, multispecialty medical centers, pharmacies, labs and more offer outstanding, personalized care for patients all across the region.
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