Mastectomy (total breast removal surgery)

What is a mastectomy?

A mastectomy is a surgical procedure that removes the breast tissue to treat breast cancer. Mastectomies may be unilateral (single mastectomy), in which one breast is removed, or bilateral (double mastectomy), in which both breasts are removed. Mastectomies differ from lumpectomy procedures in that the entire affected area of the breast as well as all the surrounding breast tissue is removed, whereas lumpectomies are only a partial removal.

Types of mastectomy procedures

We use mastectomies to treat all types of breast cancer. For early-stage cancer, mastectomy is an alternative to treatment with lumpectomy plus radiation therapy. For more advanced or recurrent cancer, mastectomy is often the best or only surgical option. For people with male breast cancer, mastectomy is often the best treatment, because most tumors in men occur beneath the nipple.

Our surgeons perform mastectomies with or without breast reconstruction. The types of mastectomies we offer include:

Who is a candidate for a mastectomy?

If you have a more high-risk or late-stage breast cancer diagnosis or an increased risk of developing breast cancer, your doctor may recommend removing one or both of your breasts to treat or prevent breast cancer. 

We may use mastectomy for many reasons, including: 

  • Large or vast tumors: Tumors that are large in size or cancer located throughout the breast cannot be treated with lumpectomy, which only removes part of the breast. 
  • High-risk cancer: Mastectomy may be recommended as a preventative measure for patients at a considerable risk for developing new or recurring breast cancer. 
  • Personal reasons: Patients may have a personal preference for mastectomy over breast conserving surgery. 

Preparing for a mastectomy

Our surgical team helps you prepare for surgery and answers any questions you may have. We coordinate pre-surgery appointments including consultations with the breast surgeon and plastic surgeon, if you plan to have breast reconstruction. 

What to expect during mastectomy surgery

The mastectomy surgery is performed using general anesthesia. During the procedure, your breast surgeon will: 

  • Make an incision around your breast and remove breast tissue for review by a pathologist 
  • Possibly remove lymph nodes for further investigation by a pathologist 
  • Work in conjunction with a plastic surgeon whenever possible to perform breast reconstruction during the mastectomy 
  • Close the incision and place temporary drains (plastic tubes) to remove any fluid build-up near the surgery site 

What to expect from mastectomy recovery

After a mastectomy, our team will monitor your heart rate, blood pressure, and other vital signs while the anesthesia wears off to ensure no complications from receiving the anesthetic. Many patients who undergo a mastectomy will return home within a day of surgery, but the hospital stay may be extended if the choice to have breast reconstruction at the same time is made. You may experience some discomfort in your chest, armpit and shoulder for a few days following surgery.

Full recovery should take approximately four weeks. Before you head home, we will walk you through the recovery instructions and offer guidance on when you can begin to wear a bra or prosthesis. We coordinate a follow-up visit with your surgeon. At that time, we will remove any drains, check the incisions, and review the pathology report. 

Breast reconstruction after mastectomy

Breast reconstruction is a surgical procedure that restores the appearance of one or both breasts following mastectomy. Plastic surgeons reconstruct the breasts using either breast implants, the patient’s own tissue (typically removed from the lower abdomen) or a combination of the two methods. 

We perform the highest volume of breast reconstructions in the nation. Our expert plastic surgeons can reconstruct your breasts at the same time as your mastectomy or at a later time. We will guide you through all your reconstruction options, so that you can make an informed decision. 

Learn more about breast reconstruction at Penn Medicine

Mastectomy: Why choose Penn Medicine?

At Penn Medicine, mastectomies involve a team of experts through our Breast Cancer Program. From preoperative education to post-surgical support, we offer compassionate care and advanced expertise every step of the way. The benefits of surgery at the Penn include: 

  • Expert surgeons: Our specialized breast surgeons perform mastectomy to fit your body and needs. If you desire a reconstruction, our plastic surgeons expertly restore your appearance. 
  • Latest surgical techniques: We perform the latest breast cancer surgeries. Our clinical trials provide access to promising new mastectomy techniques such as robotic nipple sparing surgery. 
  • Risk evaluation and counseling: Our cancer risk experts at MacDonald Cancer Risk Evaluation Center determine your risk of breast cancer. If you have a high risk of hereditary breast cancer, the Basser Center for BRCA offers specialized guidance and support. 
  • Specialty boutiques: Our cancer center boutiques, located at two Penn Medicine hospitals, offer products and services designed for breast cancer patients. We provide bra fittings and intimate apparel to help you feel confident and comfortable after mastectomy. 
National Cancer Institute Designated Comprehensive Cancer Center badge on top of shot of hospital

Rated “exceptional” by The National Cancer Institute

Penn Medicine’s Abramson Cancer Center is a world leader in cancer research, patient care, and education. Our status as a national leader in cancer care is reflected in our continuous designation as a Comprehensive Cancer Center by the National Cancer Institute (NCI) since 1973, one of 7 such centers in the United States. The ACC is also a member of the National Comprehensive Cancer Network, one of a select few cancer centers in the U.S., that are working to promote equitable access to high-quality, advanced cancer care.

Related specialties

Diverse team of doctors having a discussion

Our doctors

Our providers work with you to plan and deliver exceptional treatment and personalized care.

Panoramic shot of Penn Medicine's downtown campus

Locations

Our hospitals, multispecialty medical centers, pharmacies, labs and more offer outstanding, personalized care for patients all across the region.

Patient stories

Faith, fate, and families

Faith, fate, and families

At the Basser Center for BRCA at Penn, a unique philanthropic investment is making rapid progress toward preventing and treating heritable cancer.

A cancer dietitian, a survivor herself, keeps patients moving

A cancer dietitian, a survivor herself, keeps patients moving

Breast cancer treatments can upend a fitness routine. Cancer dietitian Dorris Piccinin, a survivor herself, is inspiring patients to keep at it.

Jamil Rivers leads women of color to better breast cancer care

Jamil Rivers leads women of color to better breast cancer care

Jamil Rivers is a full-time working mom, living with metastatic breast cancer, and leading an initiative to help other women of color navigate cancer care.

A woman's unique path to a lung cancer diagnosis

A woman's unique path to a lung cancer diagnosis

During pre-operative testing for breast cancer surgery, a patient was also diagnosed with lung cancer.

A breast cancer survivor at 28, she’s now a voice of hope

A breast cancer survivor at 28, she’s now a voice of hope

After her twin tested BRCA2-positive, Brooklyn Olumba got tested, leading to her own cancer diagnosis. Now she’s educating other young women of color.

The art of cancer recovery

The art of cancer recovery

A breast cancer survivor shares how art and a compassionate care team helped her through the challenges of cancer treatment.

Patient puts national spotlight on cancer clinical trials

Patient puts national spotlight on cancer clinical trials

As Kate Korson recently shared on Good Morning America, both she and her mother participated in clinical trials at Abramson Cancer Center.

No place like home

No place like home

Home health care is evolving from convenience to a crucial edge for the future of medicine.

Finding triple-negative breast cancer at 33, she chose ‘Team Penn’

Finding triple-negative breast cancer at 33, she chose ‘Team Penn’

Shocked to learn she had stage III breast cancer, Kate Korson knew just where to go. She flew home to Penn Medicine, where a clinical trial saved her life.

Trials aim to make cancer relapse a thing of the past

Trials aim to make cancer relapse a thing of the past

“The thought is always in the back of your head: Is it lurking? Will it come back?” Clinical trials are testing methods to stop cancer from recurring.

Schedule an appointment

We can help you schedule an appointment or you can search our directory of specialists.