Liver disease care

Penn Medicine’s liver experts deliver advanced care for hepatitis, cirrhosis, fatty liver disease, and more. We offer access to leading specialists, new treatments and research, and the region’s largest liver transplant and living-donor programs.

Organ liver in the transparent human body, 3d rendering. 3D illustration.

Specialized liver care focused on you

The liver is the largest organ in the digestive system and carries out more than 100 essential tasks. Its complexity makes it vulnerable to many conditions. Liver problems may be inherited, caused by infections, autoimmune in nature, or triggered by environmental factors. Whether you’re experiencing liver disease in early or advanced stages, experts at Penn Medicine combine advanced diagnostics with innovative therapies to address all types of liver disease.

Our clinicians focus on understanding the complexities of various liver conditions so they can bring the most advanced treatment options to you. Through a multidisciplinary approach to care, our gastroenterology and transplant surgery teams, along with radiology, pathology, and other departments, work together to provide a seamless experience for people with liver disease.

  • Liver Tumor Clinic: The Liver Tumor Clinic provides rapid access to multidisciplinary cancer management, facilitating evaluation for liver transplantation, resection, regional interventions, systemic therapy, and combinations thereof, personalized for each patient’s individual needs.
  • Ascites Clinic: Our specialized Ascites Clinic offers comprehensive treatment options for patients with refractory ascites, including access to an innovative device that automatically pumps fluid from the abdominal cavity into the bladder.
  • iLEARN Clinic: The iLEARN Clinic provides multidisciplinary management of alcohol-related liver disease, with a goal of improving liver transplantation opportunities and outcomes.

Conditions we treat

Doctor examining patient with endoscope

Advanced endoscopy for early detection and minimally invasive GI care

Our gastroenterologists provide advanced endoscopy to diagnose and treat many gastrointestinal disorders. We use the latest technology to view the digestive tract, find problems early, and provide minimally invasive care for a quicker recovery.

Pioneering treatments for all forms of liver disease

From early-stage conditions to advanced illness, Penn Medicine provides comprehensive care for all forms of liver disease. Our team includes cirrhosis specialists and other liver experts who offer advanced evaluation, treatment, and management of complex liver conditions. Those who require more advanced interventions also have direct access to the Penn Transplant Institute, one of the nation’s leading centers for liver transplantation.

3D Illustration of Human Body Organs Anatomy (Pancreas)

Unmatched experience in hepatobiliary and pancreas surgery

Penn Medicine is dedicated to ensuring the innovative treatments we develop reach the patients who need them most. We recognize that high costs and health disparities often hinder access to new treatments. To bridge these gaps, Penn Medicine is working on cost-effective, off-the-shelf CAR T therapies to reduce treatment costs. We also are enhancing access to clinical trials for underrepresented communities through community outreach and transportation support. Globally, Penn collaborates with regions like Costa Rica and Thailand to develop local manufacturing capabilities for CAR T therapies and mRNA vaccines, aiming for broader and more equitable health care access worldwide. 

Specialty clinics for advanced liver care

Penn Medicine offers several specialty clinics designed to support people with complex liver conditions. These programs bring together experts from multiple disciplines, provide coordinated care in one place, and offer access to advanced treatments, innovative devices, and ongoing support.

Diverse team of doctors having a discussion

Our doctors

Our providers work with you to plan and deliver exceptional treatment and personalized care.

Panoramic shot of Penn Medicine's downtown campus

Locations

Our hospitals, multispecialty medical centers, pharmacies, labs and more offer outstanding, personalized care for patients all across the region.

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