What is a pituitary tumor?

A pituitary tumor is an abnormal growth that forms at the base of your skull right below your brain and above your nasal passages in an area called the pituitary gland. While they are rarely cancerous, pituitary tumors can still impact your health in a variety of ways. Non-cancerous tumors are also called pituitary adenomas.

The pituitary gland is often called the “master gland” because it impacts many important bodily functions, including growth rate, sexual reproduction, and organ and gland function. This means a tumor in the pituitary gland can lead to other serious health issues. These tumors can also impact vision and memory.

The Penn Pituitary Center is a national leader in pituitary tumor diagnosis and treatment. Our patients enjoy the fastest recovery times in the country and experience the lowest rates of complication. Patients diagnosed with pituitary tumors are usually seen within a week of making an appointment.  

Types of pituitary tumors

There are two main types of pituitary tumors: 

  • Functioning: These tumors create changes in hormone production. They can affect growth, thyroid health, blood sugar, immunity, and many other important biological functions. Functioning tumors have several different subtypes that your doctor can explain to you based on your symptoms and the likelihood of diagnosis.
  • Non-functioning: While non-functioning tumors don’t cause hormonal changes, they can still cause symptoms by putting pressure on the brain and eyes.

Whether you’ve already been diagnosed with a pituitary tumor, or you suspect you may have one, you’ll want expert, compassionate treatment from leading pituitary specialists. The Penn Pituitary Center is one of the nation’s only treatment centers dedicated solely to treating pituitary conditions. We provide patients with the latest in minimally invasive treatments and advanced diagnostic approaches.

Our care team works across multiple specialty areas, such as endocrinology, neurosurgery, and otolaryngology (ENT), to collaborate on your diagnosis and develop a well-rounded treatment plan that’s right for you. 

Pituitary tumor symptoms

Symptoms of pituitary tumors vary based on type as well as size, location, and the parts of the body they affect. Many patients with pituitary tumors don’t experience any symptoms at all. If you do have symptoms, they usually occur due to tumor pressure and hormonal changes and can include:

  • Headache and migraine
  • Rapid growth 
  • Blurred vision and drooping eyelids
  • Sudden and inexplicable facial pain
  • Seizures
  • Changes in weight and menstrual cycle
  • Decreased libido 
  • Rounded face and other changes in facial features
  • Extreme changes in body temperature;
  • Thickening of body hair
  • Acne and skin discoloration
  • Extreme changes in mood
  • Changes in blood sugar

These symptoms may be concerning at first, but many of them can be managed or even eliminated once your care team diagnoses and treats your tumor.

What causes pituitary tumors?

While the exact cause of pituitary tumors is unknown, they are linked to uncontrolled cell growth in the pituitary gland. Some research indicates that these tumors can be caused by stress. In other cases, they can be traced to genetics, but most occur for unknown reasons. 

Diagnosing pituitary tumors

A pituitary tumor diagnosis starts with an assessment of your symptoms and a full physical from your doctor. They will check your vision and use blood tests to determine if you have too much cortisol (Cushing’s syndrome), growth hormone (acromegaly), or prolactin (prolactinoma).

Your doctor may also order imaging tests and specialized vision tests to identify the size and location of the tumor, as well as blood or urine tests to measure hormone levels. Penn Medicine uses the latest tools and techniques to give you the most accurate and reliable diagnosis of your pituitary condition.

MRI
An MRI provides high-resolution images of the brain, spine, and many other structures in the body.
Visual field
The visual field refers to the total area in which objects can be seen in the side (peripheral) vision as you focus your eyes on a central point. This article describes the test that measures your visual field.

Treating pituitary tumors at Penn Medicine

Some pituitary tumors don’t require any treatment beyond monitoring. Others can be managed with medication to stop the production of hormones. Surgery is often recommended for functioning tumors that are causing more serious symptoms. Your Penn Medicine care team will offer expert guidance on the best treatment plan for you, including minimally invasive techniques.  

Craniotomy
A craniotomy is a surgery that temporarily removes a small part of the skull to access the brain.
Endoscopic endonasal surgery
This minimally invasive surgery uses nasal pathways to access hard-to-reach areas near the brain and spine.
Gamma Knife
Gamma Knife radiosurgery is a blade-free surgical option for brain tumors and disorders.
Intensity-modulated radiation therapy (IMRT)
This external radiation therapy delivers varying radiation doses to different parts of a tumor.
Proton therapy
This noninvasive, precise radiation therapy uses high-energy protons to damage the DNA in cancer cells.

Related specialties

Head and neck cancer care
Get advanced, innovative head and neck cancer care from the region’s highest-volume team.
Pituitary center
Penn Medicine is a pituitary care leader offering the most skilled clinicians and best patient outcomes.
Rhinology
Our rhinology specialists treat chronic sinusitis, nasal polyps, and other nose and sinus disorders.
Skull base surgery
Our surgeons diagnose and treat head and neck tumors and other complex skull base disorders.

Patient stories

Rediscovering joy after treatment for a pituitary condition

Rediscovering joy after treatment for a pituitary condition

I felt like a completely different person… that referral saved me.

One man’s journey to find relief from facial pain

One man’s journey to find relief from facial pain

“I’ve had several surgeries, some of them pretty significant, and this was the best experience of them all,” he said. “Everyone was pleasant and engaging, and there were no issues.”

1 of 2

Schedule an appointment

We can help you schedule an appointment or you can search our directory of specialists.