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Thomas Karasic, MD

Thomas Karasic, MD Physician

Penn Medicine Clinician of Pediatrics

Dr. Karasic is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Medical Oncology

Programs & Centers:

Board Certification:

  • Internal Medicine, 2015

Clinical Expertise:

  • Appendix Cancer
  • Biological Targeted Therapy
  • Cancer Chemotherapy
  • Colon Cancer Chemotherapy
  • Esophageal Cancer
  • Esophagogastric Junction Cancer
  • Hepatobiliary Malignancies
  • Immunotherapy
  • Malignant Tumor of Extrahepatic Bile Duct
  • Neuroendocrine Tumors
  • Pseudomyxoma Peritonei
  • Small Bowel Cancer
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Columbia University
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American Association for Cancer Research, National American Society of Clinical Oncology, National Eastern Cooperative Oncology Group, National

Hospital Affiliation

Dr. Karasic is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Selected Publications:

Yarchoan M, Agarwal P, Villanueva A, Rao S, Dawson LA, Karasic TB, Llovet JM, Finn RS, Groopman JD, El-Serag HB, Monga SP, Wang XW, Karin M, Schwartz RE, Tanabe KK, Roberts LR, Gunaratne PH, Tsung A, Brown KA, Lawrence TS, Salem R, Singal AG, Kim AK, Rabiee A, Resar L, Meyer J, Hoshida Y, He AR, Ghoshal K, Ryan PB, Jaffee EM, Guha C, Mishra L, Coleman CN, Ahmed MM.: Recent Developments and Therapeutic Strategies against Hepatocellular Carcinoma Cancer Research 79 (17): 4326-4330,2019.

Karasic TB, Chiorean EG, Sebti SM, O'Dwyer PJ: A Phase I Study of GGTI-2418 (Geranylgeranyl Transferase I Inhibitor) in Patients with Advanced Solid Tumors Targeted Oncology : 2019.

Kim Anna Reiss, Rosemarie Mick, Mark H. O'Hara, Ursina R. Teitelbaum, Thomas Benjamin Karasic, Charles John Schneider, Peter J. O'Dwyer, Danielle Karlson, Stacy Cowden, Mary Jane Fuhrer, Erica L. Carpenter, Austin A Pantel, Mehran Makvandi, David A. Mankoff, Katharine Nathanson, Kara Noelle Maxwell, Gregory Lawrence Beatty, Susan M. Domchek: A randomized phase II trial of niraparib plus either nivolumab or ipilimumab in patients with advanced pancreatic cancer whose cancer has not progressed on platinum-based therapy 2019 ASCO Annual Meeting TPS4161 : 2019.

Teresa Macarulla Mercade, Victor Moreno, Binu John, John Charles Morris, Michael B. Sawyer, Wei Peng Yong, Martin Gutierrez, Thomas Benjamin Karasic, Bruno Sangro, Yang Sheng-Shun, Carleen Gentry, Amy Kim, Pavan Kumar, Crystal MacKenzie, Nathalie Rioux, Joanne Schindler, Anand Selvaraj, Richard S. Finn: A phase I study of H3B-6527 in hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICC) patients (pts) 2019 ASCO Annual Meeting Abstract #4095 : 2019.

Saima Rathore, Mark H. O'Hara, Thomas Benjamin Karasic, Maryann Redlinger, Mark Alan Rosen, Christos Davatzikos, Peter O'Dwyer: Radiomic profiles via machine learning to predict response, overall survival, and KRAS status in metastatic colorectal tumors treated with FOLFOX/bevacizumab/hydroxychloroquine 2019 ASCO Annual Meeting Abstract #e15125 : 2019.

Karasic TB, O'Hara MH, Loaiza-Bonilla A, Reiss KA, Teitelbaum UR, Borazanci E, De Jesus-Acosta A, Redlinger C, Burrell JA, Laheru DA, Von Hoff DD, Amaravadi RK, Drebin JA, O'Dwyer PJ: Effect of Gemcitabine and nab-Paclitaxel With or Without Hydroxychloroquine on Patients With Advanced Pancreatic Cancer: A Phase 2 Randomized Clinical Trial JAMA Oncology : 2019.

Kim A. Reiss Binder, Rosemarie Mick, Mark O'Hara, Ursina Teitelbaum, Thomas Karasic, Charles Schneider, Peter J. O'Dwyer, Erica Carpenter, Austin Pantel, Mehran Makvandi, David Mankoff, Katherine Nathanson, Kara Maxwell, Stacy Cowden, Mary Jane Fuhrer, Janae Romeo, Gregory L. Beatty, Susan Domchek: A Phase II, single arm study of maintenance rucaparib in patients with platinum-sensitive advanced pancreatic cancer and a pathogenic germline or somatic mutation in BRCA1, BRCA2 or PALB2 2019 AACR Annual Meeting Abstract #CT234 : 2019.

Nikhil Grandhi, Jahan Mohiuddin, John Plastaras, James M. Metz, John Lukens, Thomas Karasic, Kim Reiss-Binder, Edgar Ben-Josef, Andrzej Wojcieszynski: Outcomes of Pencil Beam Scanning Proton Therapy for Anal Cancer: A Single Institution Study American Radium Society 2019 Abstract #20 : 2019.

Kim Anna Reiss, Edgar Ben-Josef, Nevena Damjanov, Maarouf Hoteit, Thomas Benjamin Karasic, Erica Carpenter, Lisa DiCicco, Luis Anna Garcia-Marcano, Rosemarie Mick, Robert H Vonderheide: A pilot study of galunisertib (LY2157299 monohydrate) plus stereotactic body radiotherapy (SBRT) in advanced hepatocellular carcinoma (HCC) 2019 GI ASCO Abstract #270 : 2019.

Saima Rathore 1, 2, , Muhammad Aksam Iftikhar 3, Ahmad Chaddad 4, Tamim Niazi 4, Thomas Karasic 5 and Michel Bilello 1, 2: Segmentation and Grade Prediction of Colon Cancer Digital Pathology Images Across Multiple Institutions : 2019.

Academic Contact Info

3400 Civic Center Blvd
PCAM South Tower 10-102

Philadelphia, PA 19104
Phone: (215) 614-1858
Patient appointments: 800-789-7366