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Sees patients age 18 and up
Perelman Center for Advanced Medicine
South Pavilion, 1st Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
A facility of the Hospital of the University of Pennsylvania
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Dr. Rhee’s research program spans clinical and translational studies in humans that seek to understand disease pathogenesis and disease heterogeneity of multiple types of autoimmune vasculitis. Currently her research focuses on the role of the human microbiome in vasculitis and the identification of novel biomarkers in vasculitis. Dr. Rhee led the development of a biorepository of nasal swab samples from patients with ANCA-associated vasculitis, relapsing polychondritis, and healthy patients. This work combines both culture-independent advanced molecular sequencing with culture-dependent approaches to understanding how microbes interact with the immune system in autoimmune vasculitis.Dr. Rhee is also part of a multi-disciplinary team that is studying the utility of vessel wall MRI in giant cell arteritis. She works with investigators in radiology and ophthalmology to develop novel imaging biomarkers for diagnosis and disease activity in giant cell arteritis. Dr. Rhee co-led the development of the Penn Giant Cell Arteritis Fast-Track Program.
Rhee RL, Lu J, Bittinger K, Lee JJ, Mattei LM, Sreih AG, Chou S, Miner JJ, Cohen NA, Kelly BJ, Lee H, Grayson PC, Collman RG, Merkel PA: "Dynamic Changes in the Nasal Microbiome Associated with Disease Activity in Patients with Granulomatosis with Polyangiitis" Arthritis & Rheumatology : 2021.
Arnett N, Pavlou A, Burke MP, Cucchiara BL, Rhee RL, Song JW: "Vessel Wall MR Imaging of Central Nervous System Vasculitis: a Systematic Review" Neuroradiology : 2021.
Willett K, Sreih A, Rhee R, Lee V, Kwong B, Tamhankar MA: "Giant Cell Arteritis Associated with Multiple Cranial Neuropathies" Journal of Clinical Rheumatology : 2020.
Smith RM, Jones RB, Specks U, Bond S, Nodale M, Aljayyousi R, Andrews J, Bruchfeld A, Camilleri B, Carette S, Cheung CK, Derebail V, Doulton T, Forbess L, Fujimoto S, Furuta S, Gewurz-Singer O, Harper L, Ito-Ihara T, Khalidi N, Klocke R, Koening C, Komagata Y, Langford C, Lanyon P, Luqmani R, Makino H, McAlear CA, Monach P, Moreland L, Mynard K, Nachman P, Pagnoux C, Pearce F, Au Peh C, Pusey C, Ranganathan D, Rhee R, Spiera R, Sreih A, Tesar V, Walters G, Weisman M, Wroe C, Merkel PA, Jayne DRW: "Rituximab as Therapy to Induce Remission After Relapse in ANCA-Associated Vasculitis" Annals of the Rheumatic Diseases : 2020.
Quimson L, Mayer A, Capponi S, Rea B, Rhee RL: "Comparison of Aortitis Versus Noninflammatory Aortic Aneurysms Among Patients Who Undergo Open Aortic Aneurysm Repair" Arthritis & Rheumatology : 2020.
Rhee RL, Sreih A, Najem CE, Grayson PC, Zhao C, Bittinger K, Collman RG, Merkel PA: "Characterisation of the Nasal Microbiota in Granulomatosis with Polyangiitis" Annals of the Rheumatic Diseases 77 (10): 1448-53,2018.
Rennie L. Rhee, Cecile TJ Holweg, David Cuthbertson, Simon Carette, , Gary S. Hoffman, Nader A. Khalidi, Curry L. Koening, Jeffrey Krischer, Carol A. Langford, Carol A. McAlear, Paul A. Monach, Larry Moreland, Christian Pagnoux, Philip Seo, Ulrich Specks, Antoine Sreih, Steven R. Ytterberg, and Peter A. Merkel for the Vasculitis Clinical Research Consortium: "Serum Periostin as a Biomarker in Eosinophilic Granulomatosis with Polyangiitis." PLoS ONE 13 (10): e0205768,2018.
Rhee RL, Davis JC, Ding L, Fervenza FC, Hoffman GS, Kallenberg CGM, Langford CA, McCune WJ, Monach PA, Seo P, Spiera R, St Clair EW, Specks U, Stone JH, Merkel PA: “The Utility of Urinalysis in Determining the Risk of Renal Relapse in ANCA-Associated Vasculitis” Clinical Journal of the American Society of Nephrology 13 (2): 251-7,2018.
Rhee RL, Grayson PC, Merkel PA, Tomasson G: “Infections and the Risk of Incident Giant Cell Arteritis: a Population-Based, Case-Control Study" Annals of the Rheumatic Diseases 76 (6): 1031-5,2017.
Sanges S, Launay D, Rhee RL, Sitbon O, Hachulla E, Mouthon L, Guillevin L, Rottat L, Clerson P, Cordier JF, Kawut SM, Simonneau G, Humbert M.: “A Prospective Study of the 6-Minute Walk Test as a Surrogate Marker for Hemodynamics in Two Independent Cohorts of Treatment-Naïve Systemic Sclerosis-Associated Pulmonary Arterial Hypertension.” Annals of the Rheumatic Diseases 75 (8): 1457-65,2016.
Hospital of the University of PennsylvaniaDept. of Medicine/Rheumatology3400 Spruce Street5th Floor, White Building
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