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Ming-Lin Liu, MD, PhD

Ming-Lin Liu, MD, PhD Researcher

Research Assistant Professor of Dermatology

Dr. Liu is employed by Penn Medicine.

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American Diabetes Association, National American Heart Association, National American Society of Cell Biology, National American Stroke Association, National Society for Investigative Dermatology, National

Hospital Affiliation

Dr. Liu is employed by Penn Medicine.


Description of Research Expertise:

1) Cell Death and Inflammation

2) Cellular Extracellular Vesicles and Their Pathologic Roles in Human Diseases (i.e. Autoimmune and Cardiometabolic Diseases)

3) Neutrophil Extracellular Traps and Their Pathologic Roles in Human Diseases (i.e. Autoimmune and Cardiometabolic Diseases)

4) Effects of UVB Exposure on Skin Inflammation and Autoimmune Diseases (i.e. lupus, dermatomyositis, etc).

Selected Publications:

Wu X, Liu Y, Wei W*, Liu ML*: Extracellular Vesicles in Autoimmune Vasculitis - Little dirts light the fire in blood vessels Autoimmunity Reviews (in press) : 2019.

Concha JSS, Patsatsi A, Marshak-Rothstein A, Liu ML, Sinha AA, Lee LA, Merola JF, Jabbari A, Gudjonsson JE, Chasset F, Jarrett P, Chong B, Arkin L, Fernandez AP, Caproni M, Greenberg SA, Kim HJ, Pearson DR, Femia A, Vleugels RA, Fiorentino D, Fujimoto M, Wenzel J, Werth VP.: Advances in Cutaneous Lupus Erythematosus and Dermatomyositis: A report from the 4th International Conference on Cutaneous Lupus Erythematosus An ongoing need for international consensus and collaborations. J Invest Dermatol 139(2) : 270-276,2019.

ML Liu, KJ Williams, VP Werth: Microvesicles in Autoimmune Diseases Advances in Clinical Chemistry 77 : 125-175 ,2016 .

Chen Y, Li G, Liu Y, Werth VP, Williams KJ, Liu ML.: Translocation of Endogenous Danger Signal HMGB1 from Nucleus to Membrane Microvesicles in Macrophages. Journal of Cellular Physiology 231 (11): 2319-26,2016 .

Kim DK, Lee J, Kim SR, Choi DS, Yoon YJ, Kim JH, Go G, Nhung D, Hong K, Jang SC, Kim SH, Park KS, Kim OY, Park HT, Seo JH, Aikawa E, Baj-Krzyworzeka M, van Balkom BW, Belting M, Blanc L, Bond V, Bongiovanni A, Borràs FE, Buée L, Buzás EI, Cheng L, Clayton A, Cocucci E, Dela Cruz CS, Desiderio DM, Di Vizio D, Ekström K, Falcon-Perez JM, Gardiner C, Giebel B, Greening DW, Gross JC, Gupta D, Hendrix A, Hill AF, Hill MM, Nolte-'t Hoen E, Hwang DW, Inal J, Jagannadham MV, Jayachandran M, Jee YK, Jørgensen M: EVpedia: A Community Web Portal for Extracellular Vesicles Research. Bioinformatics 31 (6): 933-939,2015.

Folkesson M, Li C, Frebelius S, Swedenborg J, Wagsater D, Williams KJ, Eriksson P, Roy J, Liu ML.: Proteolytically Active ADAM10 and ADAM17 Carried on Membrane Microvesicles in Human Abdominal Aortic Aneurysms. Thrombosis and Haemostasis 114 (6): 1165-74,2015.

Liu ML, Scalia R, Mehta JL, Williams KJ: Cholesterol-induced membrane microvesicles as novel carriers of damage-associated molecular patterns: mechanisms of formation, action, and detoxification. Arteriosclerosis, Thrombosis, and Vascular Biology. 32 (9): 2113-21,2012 .

Chen K, Liu ML, Schaffer L, Li MZ, Williams KJ: Type 2 diabetes in mice induces hepatic overexpression of sulfatase 2, a novel factor that suppresses uptake of remnant lipoproteins. Hepatology. 52 : 1957-1967,2010.

Li MZ, Yu DM, Williams KJ, Liu ML.: Tobacco Smoke Induces the Generation of Procoagulant Microvesicles from Human Monocytes/Macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 30 (9): 1818-24,2010 .

Liu ML, Reilly MP, Peter Casasanto, McKenzie SE, Williams KJ.: Cholesterol Enrichment of Human Monocyte/Macrophages Induces Surface Exposure of Phosphatidylserine and the Release of Biologically-Active Tissue Factor-Positive Microvesicles. Arteriosclerosis, Thrombosis, and Vascular Biology. 27 (2): 430-5,2007 .

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Academic Contact Info

Department of Dermatology
University of Pennsylvania Health System
Perelman School of Medicine
University of Pennsylvania
2 East. Gates Building, #2021
3600 Spruce Street

Philadelphia, PA 19104