Description of Research Expertise
Retinal gene therapy
Retinal cell therapy
Retinal regeneration
Photoreceptor development
Subretinal injections
Electroretinogram
Selected Publications
O'Neil E, Qin V, Weber M, Uyhazi KE, Scoles D, Jiang Y, Maguire A, Bennett J, Morgan J, Aleman TS: Structural and Functional Relationships in RDH12-Associated Early-Onset Severe Inherited Retinal Degeneration Association for Research in Vision and Ophthalmology (ARVO) 2023 Annual Meeting (New Orleans, LA) : 2023.
Yano JJ, Wei Z, Uyhazi KE: Characterizing Subpopulations of Photoreceptor Precursor Cells During Retinal Development 150th Anniversary Meeting of the Scheie Eye Institute. (Philadelphia, PA) : 2023.
Wilder R, Duong T, Fossett G, Wei Z, Uyhazi KE: Developing Gene Therapy for Gyrate Atrophy 150th Anniversary Meeting of the Scheie Eye Institute. (Philadelphia, PA) : 2023.
Uyhazi KE, Yano JJ, Fossett G, Wei Z: Novel Populations of Photoreceptor Precursor Cells by Single Cell Transcriptomics 150th Anniversary Meeting of the Scheie Eye Institute. (Philadelphia, PA) : 2023.
Aleman TS, O'Neil EC, Uyhazi KE, Parchinski KM, Santos AJ, Weber ML, Colclough SP, Billek AS, Zhu X, Leroy BP, Bedoukian EC.: Fleck-like lesions in CEP290-associated leber congenital amaurosis: a case series Ophthalmic Genetics 43 (6): 824-833,2022.
O'Neil EC, Uyhazi KE, O'Connor K, Aleman IA, Pulido JS, Rossano JW, Aleman TS.: DANON DISEASE: A MODEL OF PHOTORECEPTOR DEGENERATION SECONDARY TO PRIMARY RETINAL PIGMENT EPITHELIUM DISEASE Retin Cases Brief Rep 16 : 707-713,2022.
Vrathasha V, Nikonov S, Bell BA, He J, Bungatavula Y, Uyhazi KE, Murthy Chavali VR.: Transplanted human induced pluripotent stem cells- derived retinal ganglion cells embed within mouse retinas and are electrophysiologically functional iScience 25 : 105308,2022.
Margaritis P, Bennett J, Chomistek S, Vasireddy V, Shpylchak I, Wei Z, Luo A, Sun J, Zhou S, Pham J, Maguire AM, Uyhazi K, Aleman TS: Preparation for a Gene Therapy Trial for LCA5-Associated Retinal Degenerations: Treatment Potential in Patients and Dose-ranging Studies in Non-human Primates Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting (Denver, CO) : 2022.
Aleman TS, O’Neil EC, Uyhazi KE, Bennett J: Retinal Degenerations in the Era of Commercially-Available Molecular Screening 148th Anniversary Meeting of the Scheie Eye Institute. (Philadelphia, PA) : 2022.
O’Neil E, Uyhazi K, Scavelli K, O’Connor K, Shagena E, Jiang YY, Maguire AM, Morgan J, Bennett J, Aleman TS: Central Structural and Functional Abnormalities in Choroideremia: Longitudinal and Cross-sectional Observations from a Large Cohort of Patients Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting (Denver, CO) : 2022.
Academic Contact Information
Stellar Chance Laboratories, Rm 313A
422 Curie Blvd
Philadelphia,
PA
19104
Phone: 215-662-8816
Patient appointments: 800-789-7366