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Adults (18-65), Geriatrics (65+)
Adults (18-65), Geriatrics (65+)
Perelman Center for Advanced Medicine
West Pavilion, 1st Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
A facility of the Hospital of the University of Pennsylvania
J.C. Thompson, C. Davis, C. Deshpande, W. Hwang, S. Jeffries, A. Huang, T.C. Mitchell, C.J. Langer, S.M. Albelda: A gene signature of antigen processing and presentation machinery (APM) predicts response to checkpoint blockade in Non-Small Cell Lung Cancer (NSCLC) and melanoma Journal for ImmunoTherapy of Cancer : 2020.
C. Aggarwal, J.C Thompson, A. Chien, K. Quin, W. Hwang, T. Black, S.S. Yee, T. Christensen, M. LaRiviere, B. Silva, K. Banks, R. Nagy, E. Helman, A. Berman, C.A. Ciunci, A. Singh, J. Wasser, J.M. Bauml, C.J. Langer, R. B. Cohen, E.L. Carpenter: Baseline plasma tumor mutation burden predicts response to pembrolizumab-based therapy in patients with metastatic non-small cell lung cancer Clinical Cancer Research : 2020.
J.C. Thompson, W. Hwang, C. Davis, C. Deshpande, S. Jeffries, Y. Rajpurohit, V. Krishna, D. Smirnov, R. Verona, M.V. Lorenzi, C.J. Langer, S.M. Albelda: Gene Signatures of Tumor Inflammation and Epithelial-to-Mesenchymal Transition (EMT) Predict Responses to Immune Checkpoint Blockade in Lung Cancer with High Accuracy Lung Cancer : 2019.
C. Aggarwal*, J.C Thompson*, T. Black, S. Katz, R. Fan, S.S Yee, A. Chien, T.L. Evans, J. Bauml, E. Alley, C. Ciunci, A. Berman, R. Cohen, D. Lieberman, K. Majmundar, S.L Savitch, J.D. Morrissette, W. Hwang, K. Elenitoba-Johnson, C.J. Langer, E.L. Carpenter.: Clinical implications of plasma-based genotyping with the delivery of personalized therapy in metastatic non–small cell lung cancer. JAMA Oncology 5 (2): 173-180,2019.
J. Kargl, X. Zhu, H. Zhang, G. Yang, T. Riesen, M. Shipley, D. Maeda, J. Zebala, J. Mckay-Fleisch, G. Meredith, A. Mashadi-Hossein, C. Baik, R.H. Pierce, M.W. Redman, J.C. Thompson, S.M. Albelda, H. Bolouri, A.M. Houghton: Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC JCI Insight : 2019.
Klampatsa S. O’Brien, J. C. Thompson, S. A.S. Rao, J.E. Standalick, M. Martinez, M. Liousia, E. Cantu, K. Cengel, E. Moon E, S. Singhal, E.B. Eruslanov, S.M Albelda: Phenotypic and Functional Analysis of Malignant Mesothelioma Tumor-Infiltrating Lymphocytes (TILs) Oncoimmunology : 2019.
C. Aggarwal, C. Davis, R. Mick, J.C. Thompson, S. Ahmed, S. Jeffries, S. Bagley, P. Gabriel, T.L. Evans, J. Bauml, C. Ciunci, E. Alley, J.D. Morrissette, R. Cohen, E.L. Carpenter, C. Langer: Influence of TP53 Mutation on Survival and Transformation to Small Cell Lung Cancer in Patients with Advanced EGFR-Mutant Non-Small Cell Lung Cancer JCO Precision Oncology published on line : 2018.
S.M Obrien, A. Klampatsa, J.C.Thompson, M. Martinez, W. Hwang, A. Rao, J. Standalick, S. Kim, E. Cantu, L. Litzky, S. Singhal, E. Eruslanov, E.K. Moon, S.M. Albelda: Function of Human Tumor Infiltrating Lymphocytes in Early Stage Non-Small Cell Lung Cancer Cancer Immunology Research : 2019.
J.C. Thompson, R. Fan, T. Black, G.H. Yu, S.L. Savitch, A. Chien, S. Yee, M. Sen, W. Hwang, S.I. Katz, M. Feldman, A. Vachani, E.L. Carpenter.: Measurement and Immunophenotyping of pleural EpCAM-positive cells and clusters for the management of non-small cell lung cancer patients. Lung Cancer 127 : 25-33,2019.
M. Marmarelis, E. Bange, W. Hwang, Y. Yang, J.C. Thompson, J. Rosenbaum, J. Bauml, C.Ciunci, E. Alley, R. Cohen, C. Langer, E. Carpenter, C. Aggarwal: Impact of KRAS and TP53 co-mutations on outcomes following first-line systemic among patient with STK11 mutated advanced NSCLC JCO Precision Oncology : 2019.
M. Marmarelis, J.C. Thompson, C. Aggarwal, T.L. Evans, E. Carpenter. R.B. Cohen, C.J. Langer, J. Bauml.: Emerging uses of circulating tumor DNA in advanced stage non-small cell lung cancer.
Ann Transl Med.
5 (18): 380,2017.
S. Katz, M. Hammer, S.J. Bagley, C. Aggarwal, J. Bauml, J.C. Thompson, A.C. Nachiappan, C.B. Simone, C. Langer.: Radiologic pseudoprogression during anti-PD1 therapy for advanced non-small lung cancer. J Thorac Oncol.
13 (7): 978-986,2018.
J. C. Thompson, S.S Yee, A.B. Troxel, S.L. Savitch, R. Fan, D. Balli, D.B. Lieberman, J.D Morrissette, T.L Evans, J. Bauml, C. Aggarwal, J.A Kosteva, E. Alley, C. Ciunci, R.B. Cohen, S. Bagley, S. Stonehouse-Lee, V.E. Sherry, E. Gilbert, C. Langer, A. Vachani, E. Carpenter: Detection of Therapeutically Targetable Driver and Resistance Mutations in Lung Cancer Patients by Next-Generation Sequencing of Cell-Free Circulating Tumor DNA. Clinical Cancer Research 22 (23): 5772-5782,2016.
S.J. Bagley, S. Kothari, C. Aggarwal, J. Bauml, E. Alley, T.L Evans, J.A. Kosteva, C. Ciunci, J.C. Thompson, S. Stonehouse-Lee, V.E. Sherry, E. Gilbert, B. Sandy, F. Mutale, G. DiLullo, R.B. Cohen, A. Vachani, C. Langer.: Pretreatment neutrophil-to-lymphocyte ratio as a marker of outcomes in nivolumab treated patients with advanced non-small cell lung cancer. Lung Cancer 106 : 1-7,2017.
221 Stemmler Hall3450 Hamilton Walk
Patient appointments: 800-789-7366