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Deborah A. Driscoll, MD

Deborah A. Driscoll, MD Physician

Chair, Department of Obstetrics and Gynecology Luigi Mastroianni, Jr. Professor of Obstetrics and Gynecology

Dr. Driscoll is employed by Penn Medicine.

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About Dr. Deborah A. Driscoll

Recognized by America's Top Doctors, 2007, 2008, 2010, and 2014 - 2018

Recognized by Best Doctors in America 2003 - 2012, and 2015 - 2018

Recognized annually in Philadelphia magazine's annual Top Docs issues from 2006 through 2012, 2018 and 2019

Clinical Specialties


  • Obstetrics and Gynecology

Programs & Centers:

Board Certification:

  • Medical Genetics - Clinical Genetics, 1990
  • Medical Genetics, 1990
  • Obstetrics and Gynecology, 1991

Clinical Expertise:

  • Amniocentesis
  • Birth Defects and Disorders
  • Chorionic Villus Sampling
  • Chromosomal Microarray Analysis
  • Chromosome Aberration
  • Chromosome Deletion
  • Chromosome Duplication
  • Expanded Carrier Genetic Screening
  • Family History of Chromosomal Anomaly
  • Fetal Abnormalities
  • Inherited Genetic Disorders
  • Multiple Congenital Anomalies and Birth Defects
  • Prenatal Diagnosis
  • Prenatal Genetic Counseling
  • Prenatal Ultrasound Scan

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • Consumer Health Network
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Amerihealth
  • NJ Medicaid
  • NJ Medicare
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: New York University School of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


American Board of Obstetrics & Gynecology, National American College of Medical Genetics (ACMG), Founding Fellow, National American College of Obstetricians and Gynecologists (ACOG), Fellow, National American Gynecological and Obstetrical Society, National American Medical Association, American Society of Human Genetics (ASHG), Association of Professors of Gynecology and Obstetrics (APGO), Biomedical Research & Education Foundation, Medical Advisory Board, 2004-present, Council of University Chairs of Obstetrics and Gynecology, National Foundation for Excellence in Women’s Health, National Genetic Counseling Master's Program, Advisory committee, Arcadia University, 2001-2002, International 22q11 Chromosome Deletion Foundation Medical Advisory Board, 2004-present, March of Dimes, National March of Dimes, Review Committee for Genetics & Your Practice Online, 2002-2003, NHLBI, ad hoc reviewer, NICHD, Women's Health Reproductive Research Centers, Advisory Committee, North American Society of Pediatrics and Adolescent Gynecology (NASPAG), Reproductive Scientist Development Program, Executive Committee,

Hospital Affiliation

Dr. Driscoll is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.
  • Princeton HealthCare System: Has privileges to treat patients in the hospital.


Description of Research Expertise:

22q11.2 deletion syndrome, preterm birth

Selected Publications:

Driscoll, D.A., Budarf, M.L., Emanuel, B.S.: A genetic etiology for DiGeorge syndrome: consistent deletions and microdeletions of 22q11. Am. J. Hum. Genet. 50 : 924-933,1992.

Driscoll, D.A., Spinner, N.B., Budarf, M.L., McDonald-McGinn, D.M., Zackai, E.H., Goldberg, R.B., Shprintzen, R.J., Saal, H.M., Zonana, J., Jones, M.C., Mascarello, J.T., Emanuel, B.S.: Deletions and microdeletions of 22q11.2 in velo-cardio-facial syndrome. Am. J. Med. Genet. 44 : 261-268,1992.

McLean, S.D., Saal, H.M., Spinner, N.B., Emanuel, B.S. and Driscoll, D.A.: Velo-cardio-facial syndrome: Intra-familial variability of the phenotype. Am. J. Dis. Child. 147 : 1212-1216,1993.

Junker A.K. and Driscoll, D.A.: Humoral Immunity in DiGeorge syndrome. J. of Peds 127 : 231-237,1995.

Driscoll, D.A. and Emanuel, B.S.: DiGeorge and velocardiofacial syndrome: the 22q11 deletion syndrome. Mental Retardation and Developmental Disabilities Research Reviews 2 : 130-138,1996.

Goldmuntz E., Clark, B.J., Mitchell, L.E., Jawad, A.F., Reed, L., McDonald-McGinn, DM., Cuneo, B.F., Chien, P., Feuer, J., Zackai, E.H., Emanuel, B.S., Driscoll, D.A.: Frequency of 22q11 deletions in patients with conotruncal defects. J. Am. College of Cardiology 32 : 492-498,1998.

Driscoll DA, Morgan MA, Schulkin J: Screening for Down syndrome: changing practice of obstetricians Am J Obstet Gynecol 200 (459): 2009.

Wapner RJ, Driscoll DA, Simpson JL: Integration of microarray technology into prenatal diagnosis: counseling issues generated during the NICHD clinical trial. Prenat Diagn 32 : 396-400,2012.

Academic Contact Info

Department of Obstetrics and Gynecology
Hospital of the University of Pennsylvania
3400 Spruce Street

Philadelphia, PA 19104-4283
Phone: (215) 662-7503
Patient appointments: 800-789-7366 (PENN)

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