RESEARCH INTERESTS: Biomarker studies in neurodegenerative diseases.
KEY WORDS: frontotemporal degeneration, neurolinguistics, social disorders, executive functioning, neuroimaging, cerebrospinal fluid, plasma, genetics
DESCRIPTION OF RESEARCH: We assess behavioral, imaging and biofluid measures in patients with frontotemporal degeneration spectrum disorders, including primary progressive aphasia, behavioral variant FTD, amyotrophic lateral sclerosis, corticobasal degeneration and progressive supranuclear palsy. We also study parkinson spectrum disorders. The goal is to identify the best set of behavioral, neuroimaging and biofluid measures that reflect the underlying proteinopathy in each of these patient groups. We participate in clinical treatment trials.