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Xiao Zhao, MD

Xiao Zhao, MD Physician

Instructor A of Medicine

Dr. Zhao is employed by Penn Medicine.

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Clinical Specialties


  • Gastroenterology

Programs & Centers:

Board Certification:

  • Gastroenterology, 2015
  • Internal Medicine, 2011

Clinical Expertise:

  • Gastroscopy
  • Liver Diseases

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Vetrans Choice Program (6/2018 Not Active)

Education and Training

Medical School: Mount Sinai School of Medicine
Residency: Yale-New Haven Hospital
Fellowship: Hospital of the University of Pennsylvania


American Association for the Study of Liver Disease, National

Hospital Affiliation

Dr. Zhao is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Radnor: Has privileges to perform procedures.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Zhao, X, Lorent K, Wilkins B, Marchione DM, Gillespie K, Waisbourd-Zinman O, So J, Koo KA, Shin D, Porter JR, Wells RG, Pack M.: Glutathione Antioxidant Pathway Activity and Reserve Determine Toxicity and Specificity of the Biliary Toxin Biliatresone in Zebrafish. Hepatology : 2016.

Waisbourd-Zinman O, Koh H, Tsai S, Lavrut P, Dang C, Zhao X, Pack M, Cave J, Hawes M, Koo KA, Porter JR, Wells RG.: The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis via decreased glutathione and SOX17. Hepatology : 2016.

Lorent K, Gong W, Koo KA, Waisbourd-Zinman O, Karjoo S, Zhao X, Sealy I, Kettleborough R, Stemple DL, Windsor PA, Whittaker SJ, Porter JR, Wells RG, Pack M.: Identification of a Plant Isoflavonoid that Causes Biliary Atresia Science Translational Medicine : 2015.

Zhao X, Monson C, Gao C, Gouon-Evans V, Matsumoto N, Sadler KC, Friedman S: Klf6/copeb is required for endoderm development and hepatic outgrowth in zebrafish and mouse ES cells Developmental Biology : 2010.

Yea S, Narla G, Zhao X, Garg R, Tal-Kremer S, Hod, E, Villaneuva A, Like J, Tarocchi, M, Shirasawa S, Sasazuk T, Martignetti J, Llovet J, Friedman S.: Oncogenic Ras promotes cellular growth by enhancing alternative splicing-mediated inactivation of the KLF6 tumor suppressor Oncogene : 2008.

Narla G, Tal-Kremer S, Matsumoto N, Zhao X, Yao S, Kelley K, Tarocchi M, Friedman S.: In vivo regulation of p21 by the Klf6 tumor suppressor gene in mouse liver and human hepatocellular carcinoma. Oncogene : 2007.

Academic Contact Info

421 Curie Boulevard
11th Floor, Biomedical Research Building II/III

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)