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Xiao Zhao, MD

Xiao Zhao, MD Physician

Instructor A of Medicine

Dr. Zhao is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties

Specialty:

  • Gastroenterology

Programs & Centers:

Board Certification:

  • Gastroenterology, 2015
  • Internal Medicine, 2011

Clinical Expertise:

  • Abdominal Bloating
  • Abdominal Disorders
  • Abdominal Distention
  • Abdominal Pain
  • Abnormal Liver Function
  • Abnormal Stool
  • Acute Pancreatitis
  • Alcoholic Liver Disease
  • Altered Bowel Habits
  • Anal Pain
  • Anal Spasm
  • Annular Pancreas
  • Anorexia
  • Autoimmune Enteropathy
  • Autoimmune Hepatitis
  • Barrett's Esophagus
  • Benign Neoplasm of Colon
  • Blood in Stool
  • Bowel Disorders
  • Bowel Dysmotility
  • Bowel incontinence (Fecal Incontinence)
  • Bright Red Blood in Rectum
  • C. Difficile (Clostridium Difficile Diarrhea)
  • Celiac Disease (Celiac Sprue)
  • Cholangitis
  • Cholecystitis
  • Cholelithiasis
  • Cholestasis
  • Chronic Diarrhea
  • Chronic Pancreatitis
  • Colitis
  • Collagenous Colitis
  • Colonic Inertia
  • Colonic Polyps
  • Colonoscopy
  • Constipation
  • Crigler Najjar Syndrome
  • Crohn's Disease
  • Cyclic Vomiting Syndrome
  • Difficulty Swallowing (Dysphagia)
  • Digestive Conditions
  • Diverticular Disease
  • Diverticulitis (Colonic Diverticulitis)
  • Duodenal Ulcer
  • Duodenitis
  • Dyspepsia
  • Early Satiety
  • Eosinophilic Colitis
  • Eosinophilic Enteritis
  • Eosinophilic Esophagitis (EoE)
  • Eosinophilic Gastritis
  • Epigastric Pain
  • Eructation
  • Esophageal Achalasia
  • Esophageal Disorders
  • Esophageal Motility Disorders
  • Esophageal Spasm
  • Esophageal Stricture
  • Esophageal Thickening
  • Esophageal Ulcer
  • Esophageal Varices
  • Esophagitis
  • Esophagus Tumors
  • Fatty Liver Diseases
  • Fecal Impaction
  • Feeding Tube Management
  • Flatulence
  • Focal Nodular Hyperplasia
  • Gallbladder Disorders
  • Gallbladder Polyp
  • Gastric Anomaly
  • Gastric Ulcer
  • Gastritis
  • Gastroenteritis
  • Gastroesophageal Reflux Disease (GERD)
  • Gastrointestinal Amyloid
  • Gastrointestinal Bleeding
  • Gastrointestinal Cancer Screening
  • Gastrojejunal Ulcer
  • Gastroparesis
  • Gastroscopy
  • Giardiasis
  • Gluten Sensitivity
  • H. Pylori Infection
  • Hematemesis
  • Hemochromatosis
  • Hepatitis
  • Hepatitis B
  • Hepatitis C
  • Hepatomegaly
  • Hereditary Nonpolyposis Colorectal Cancer
  • Hiatal Hernia
  • Ileitis
  • Inflammatory Bowel Disease (IBD)
  • Intestinal Obstruction
  • Intestinal Pseudo-Obstruction
  • Intractable Vomiting
  • Irritable Bowel Syndrome
  • Ischemic Colitis
  • Jaundice
  • Lactose Intolerance
  • Liver Cirrhosis
  • Liver Diseases
  • Liver Mass
  • Lymphocytic Colitis
  • Malabsorption
  • Melena
  • Microscopic Colitis
  • Motility Disorders
  • Nausea
  • Non-Alcoholic Fatty Liver Disease
  • Obstipation
  • Obstructive Jaundice
  • Odynophagia
  • Pancreas Divisum
  • Pancreatic Cyst
  • Pancreatic Insufficiency
  • Pancreatic Pseudocyst
  • Pancreaticobiliary Disease
  • Pancreatitis
  • Peptic Ulcer Disease (Stomach Ulcers)
  • Peritonitis
  • Pernicious Anemia
  • Peutz-Jeghers Syndrome
  • Polyposis Syndrome
  • Portal Hypertension
  • Portal Hypertensive Gastropathy
  • Postprandial Diarrhea
  • Proctitis
  • Proctosigmoidoscopy
  • Rectal Bleeding
  • Rectal Disorders
  • Short Bowel Syndrome (Short Gut Syndrome)
  • Sigmoidoscopy
  • Small Bowel Disease
  • Steatorrhea
  • Stomach Cramps
  • Stomach Disorders
  • Swallowing Disorders
  • Toxic Liver Injury
  • Ulcerative Colitis
  • Upper GI Endoscopy
  • Vomiting
  • Whipple's Disease
  • Wilson's Disease
  • Zenker's Diverticulum
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Mount Sinai School of Medicine
Residency: Yale-New Haven Hospital
Fellowship: Hospital of the University of Pennsylvania

Memberships

American Association for the Study of Liver Disease (Member), National American Gastroenterological Association (Member), National

Hospital Affiliation

Dr. Zhao is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Radnor: Has privileges to perform procedures.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Selected Publications:

Estrada MA, Zhao X, Lorent K, Kriegermeier A, Nagao SA, Berritt S, Wells RG, Pack M, Winkler JD.: Synthesis and structure-activity relationship study of biliatresone, a plant isoflavonoid that causes biliary atresia. ACS Med Chem Lett 14 (9): 61-64,2017.

Zhao X, Lorent K, Pack M.: Heritable variation of redox homeostasis is a potential risk factor for biliary disease. American Association for the Studies of Liver Diseases Annual Meeting, Washington DC : 2017.

Zhao X, Pack M.: Modeling intestinal disorders using zebrafish. The Zebrafish: Disease Models and Chemical Screens. 138 : 241-270,2017.

Zhao X, Ramakrishnan R, Loomes K, Spinner N, Pack M.: Heat shock chaperon STIP1 as a modulator and genetic risk factor of extra-hepatic biliary atresia. American Association for the Studies of Liver Diseases Annual Meeting, Washington DC : 2017.

Zhao, X, Lorent K, Wilkins B, Marchione DM, Gillespie K, Waisbourd-Zinman O, So J, Koo KA, Shin D, Porter JR, Wells RG, Pack M.: Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish. Hepatology 64 (3): 894-907,2016.

Waisbourd-Zinman O, Koh H, Tsai S, Lavrut P, Dang C, Zhao X, Pack M, Cave J, Hawes M, Koo KA, Porter JR, Wells RG.: The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis via decreased glutathione and SOX17. Hepatology 64 (3): 880-93,2016.

Lorent K, Gong W, Koo KA, Waisbourd-Zinman O, Karjoo S, Zhao X, Sealy I, Kettleborough R, Stemple DL, Windsor PA, Whittaker SJ, Porter JR, Wells RG, Pack M.: Identification of a Plant Isoflavonoid that Causes Biliary Atresia Science Translational Medicine : 2015.

Zhao X, Wilkins B, Lorent K, Wells R, Pack M.: GSH depletion is critical for the early pathogenesis of BA in the toxin-induced BA model. American Association for the Studies of Liver Diseases Annual Meeting, San Francisco, CA : 2015.

Zhao X, Lorent K, Gong WL, Koo, KK, Porter J, Wells R, Pack M.: The zebrafish ductbend mutation is a sensitizer to toxin-induced biliary atresia and a potential homologue of a human biliary atresia modifier. American Association for the Studies of Liver Diseases Annual Meeting, Boston, MA. : 2014.

Zhao X, Wajahat M.: Three single nucleotide polymorphisms of genes involved in innate immunity are associated with early viral response in Caucasian patients treated for Hepatitis C. American Association for the Studies of Liver Diseases Annual Meeting, San Francisco, CA : 2011.

Academic Contact Info

Division of Gastroenterology
421 Curie Boulevard
BRB II/III Rm 914

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)