Estrada MA, Zhao X, Lorent K, Kriegermeier A, Nagao SA, Berritt S, Wells RG, Pack M, Winkler JD.: Synthesis and structure-activity relationship study of biliatresone, a plant isoflavonoid that causes biliary atresia. ACS Med Chem Lett 14 (9): 61-64,2017.
Zhao X, Lorent K, Pack M.: Heritable variation of redox homeostasis is a potential risk factor for biliary disease.
American Association for the Studies of Liver Diseases Annual Meeting, Washington DC
Zhao X, Pack M.: Modeling intestinal disorders using zebrafish. The Zebrafish: Disease Models and Chemical Screens. 138 : 241-270,2017.
Zhao X, Ramakrishnan R, Loomes K, Spinner N, Pack M.: Heat shock chaperon STIP1 as a modulator and genetic risk factor of extra-hepatic biliary atresia. American Association for the Studies of Liver Diseases Annual Meeting, Washington DC : 2017.
Zhao, X, Lorent K, Wilkins B, Marchione DM, Gillespie K, Waisbourd-Zinman O, So J, Koo KA, Shin D, Porter JR, Wells RG, Pack M.: Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish. Hepatology 64 (3): 894-907,2016.
Waisbourd-Zinman O, Koh H, Tsai S, Lavrut P, Dang C, Zhao X, Pack M, Cave J, Hawes M, Koo KA, Porter JR, Wells RG.: The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis via decreased glutathione and SOX17. Hepatology 64 (3): 880-93,2016.
Lorent K, Gong W, Koo KA, Waisbourd-Zinman O, Karjoo S, Zhao X, Sealy I, Kettleborough R, Stemple DL, Windsor PA, Whittaker SJ, Porter JR, Wells RG, Pack M.: Identification of a Plant Isoflavonoid that Causes Biliary Atresia Science Translational Medicine : 2015.
Zhao X, Wilkins B, Lorent K, Wells R, Pack M.: GSH depletion is critical for the early pathogenesis of BA in the toxin-induced BA model. American Association for the Studies of Liver Diseases Annual Meeting, San Francisco, CA : 2015.
Zhao X, Lorent K, Gong WL, Koo, KK, Porter J, Wells R, Pack M.: The zebrafish ductbend mutation is a sensitizer to toxin-induced biliary atresia and a potential homologue of a human biliary atresia modifier.
American Association for the Studies of Liver Diseases Annual Meeting, Boston, MA. : 2014.
Zhao X, Wajahat M.: Three single nucleotide polymorphisms of genes involved in innate immunity are associated with early viral response in Caucasian patients treated for Hepatitis C. American Association for the Studies of Liver Diseases Annual Meeting, San Francisco, CA : 2011.