Description of Research Expertise:
Brain-machine interface / Brain-computer interface
Implantable sensors
Motor Cortex Functional Organization
Voluntary Movement
Speech and Language Organization
Cortical Plasticity
Gene therapy
Basal Ganglia - Cortical Interactions
Cortical/Basal Ganglia Stimulation
Cortical Spike and Local Field Recording
Basal Ganglia Spike and Local Field Recording
Neuroprosthetics
Spinal Cord Stimulation and Mapping
Electromyography
Selected Publications:
Richardson, AG, Y Ghenbot, X Liu, H Has, C Rinehart, S DeLuccia, ST Maldonado, G Boyek, M Zhang, F Aflatouni, J Van der Spiegel, TH Lucas: Learning active sensing strategies using a sensory brain-machine interface PNAS 116 (35): 17509-14,2019.
Kini, LG, JM Bernabei, F Mikhail, P Hadar, P Shah, AN Khambhati, K Oechsel, R Archer, J Boccanfuso, E Conrad, RT Shinohara, J Stein, S Das, A Kheder, TH Lucas, KA Davis, DS Bassett, B Litt: Virtual resection predicts surgical outcome for drug resistant epilepsy Brain 142 (12): 3892-3905,2019.
Khambhati AN, AE Kahn, J Costantini, Y Ezzyat, E Solomon, RE Gross, BC Jobst, SA Sheth, KA Zaghloul, G Worrell, S Seger, BC Lega, S Weiss, MR Sperling, R Gorniak, SR Das, JM Stein, DS Rizzuto, MJ Kahana, TH Lucas, KA Davis, JI Tracey, BS Bassett.: Functional control of electrophysiological network architecture using direct neurostimulation in humans Network Neuroscience, MIT Press 3 (3): 848-877,2019.
Jacob F, R Salinas, D Zhang, P Nguyen, GL Ming, D Petrov, TH Lucas, HI Chen, D O'Rourke, Song H: A patient-derived glioblastoma organoid model and biobank recapitulates inter- and intra-tumor heterogeneity Cell In press : 1-9,2019.
Shah P, JM Bernadbei, L Kini, A Ashourvan, J Boccanfuso, R Archer, K Oechsel, SR Das, JM Stein, TH Lucas, DS Bassett, KA Davis and B Litt: High intertidal connectivity within the resection zone is associated with favorable post-surgical outcomes in focal epilepsy patients NeuroImage 23 : 101908-19,2019.
Stiso, J, AN Khambhati, T Mernara, AE Kahn, J Stein, SR Das, R Gorniak, J Tracy, B Litt, KA Davis, F Pasqualetti, TH Lucas, DS Bassett: White matter network architecture guides direct electrical stimulation through optimal state transitions Cell Reports 28 (10): 2554-66,2019.
Vitale F, M Allen, K Cullen, AG Richardson, TH Lucas, B Litt: Biomimetic extracellular matrix coatings improve the chronic biocompatibility of microfabricated subdural microelectrode arrays PLoS One 13 (11): e0206137,2018.
Driscoll N, AG Richardson, K Maleski, B Anasori, O Adewole, P Lelyukh, L Escobedo, K Cullen, TH Lucas, Y Gogotsi, F Vitale: Two-Dimensional TiC MXene for High-Resolution Neural Interfaces. ACS Nano: Journal of American Chemical Society 12 (10): 10419-10429,2018.
Gourmaud S, H Shou, DJ Irwin, K Sansalone, L Jacobs, TH Lucas, ED Marsh, KA Davis, FE Jensen, DM Talos: Alzheimer's like amyloid and tau pathology associated with cognitive deficit in temporal lobe epilepsy Brain 143 (1): 191-209,2019.
Agarwal Prateek, Abdullah Kalil G, Ramayya Ashwin G, Nayak Nikhil R, Lucas Timothy H: A Retrospective Propensity Score-Matched Early Thromboembolic Event Analysis of Prothrombin Complex Concentrate vs Fresh Frozen Plasma for Warfarin Reversal Prior to Emergency Neurosurgical Procedures. Neurosurgery 82 (6): 877-886,2018.
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