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Tessa S. Cook, MD, PhD

Tessa S. Cook, MD, PhD Physician

Director, 3-D and Advanced Imaging Laboratory Director, Center for Translational Informatics Assistant Professor of Radiology at the Hospital of the University of Pennsylvania

Dr. Cook is employed by Penn Medicine.

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Clinical Specialties


  • Radiology

Programs & Centers:

Board Certification:

  • Diagnostic Radiology, 2012

Clinical Expertise:

  • Angiography
  • Arthrogram
  • Aspiration
  • Biopsy
  • CT Scan (Computed Tomography)
  • CT Scan Guided Biopsy
  • CT Scan Guided Injection
  • CTA (Computed Tomography Angiography)
  • Diagnostic Imaging
  • Diagnostic Test
  • Dilation
  • Elastography
  • Fistulogram
  • Fluoroscopy
  • Insufficiency Fracture
  • Lesion of Testis
  • Lung Cancer Screening
  • Magnetic Resonance Venography (MRV)
  • Minimally Invasive Surgery
  • MRA (Magnetic Resonance Angiography)
  • MRI (Magnetic Resonance Imaging)
  • MRI Guided Biopsy
  • Musculoskeletal Tumor
  • Nuclear Imaging
  • Pyelogram
  • Renal Mass
  • Stent Placement
  • Steroid Injection
  • Ultrasound
  • Ultrasound Guided Biopsy
  • Ultrasound Guided Injection
  • Urogram
  • Venography
  • X-Ray
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Amerihealth
  • NJ Medicaid
  • NJ Medicare
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program
  • Vibra Health Plan

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Pennsylvania Hospital
Residency: Hospital of the University of Pennsylvania


American Board of Imaging Informatics, National American Board of Radiology, International American College of Radiology, National American Roentgen Ray Society (ARRS), National Association of University Radiologists (AUR), National Diagnostic Imaging, International European Society of Radiology, International Pennsylvania Radiological Society, Local Philadelphia Roentgen Ray Society, Local Society for Cardiovascular Magnetic Resonance, International Society for Imaging Informatics in Medicine (SIIM), International SPIE, International United Kingdom National Institute for Health Research, International

Hospital Affiliation

Dr. Cook is employed by Penn Medicine.

Hospital Privileges:

  • Chester County Hospital: Has privileges to treat patients in the hospital.
  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

- imaging informatics
- workflow optimization
- artificial intelligence
- follow-up monitoring
- innovation

- radiation dose monitoring
- radiation dose reduction
- mobile apps for radiology education

Selected Publications:

Jackson M Steinkamp, Charles Chambers, Darco Lalevic, Hanna M Zafar, Tessa S Cook: Toward Complete Structured Information Extraction from Radiology Reports Using Machine Learning J Dig Img 32 (4): 554-564,2019.

CA Umscheid, Jonathan Wilen, Matthew Garin, JD Goldstein, TS Cook, Yulun Liu, Yong Chen, JS Myers: National Survey of Hospitalists' Experiences with Incidental Pulmonary Nodules Journal of Hospital Medicine 46 (6): 353-356,2019.

Langlotz CP, Allen B, Erickson BJ, Kalpathy-Cramer J, Bigelow K, Cook TS, Flanders AE, Lungren MP, Mendelson DS, Rudie JD, Wang G, Kandarpa K: A roadmap for foundational research on artificial intelligence in medical imaging: From the 2018 NIH/RSNA/ACR/The Academy Workshop Radiology 291 (3): 781-791,2019.

Liao GJ, Liao JM, Lalevic D, Zafar Hm, Cook TS: Location, Location, Location: The Association Between Imaging Setting and Follow-Up of Findings of Indeterminate Malignant Potential J Am Coll Rad 16 (6): 781-787,2019.

Martin-Carreras T, Cook TS, Kahn Jr CE: Readability of radiology reports: implications for patient-centered care Clinical Imaging 54 : 116-120,2019.

Cho JK, Zafar HM, Lalevic D, Cook TS: Patient Factor Disparities in Imaging Follow-Up Rates After Incidental Abdominal Findings AJR Am J Roentgenol 212 (3): 589-595,2019.

Vey BL, Cook TS, Nagy P, Bruce RJ, Filice RW, Wang KC, Safdar NM: A Survey of Imaging Informatics Fellowships and Their Curricula: Current State Assessment J Dig Img 32 (1): 91-96,2019.

George Shih, Carol C Wu, Safwan S Halabi, Marc D Kohli, Luciano M Prevedello, Tessa S Cook, Arjun Sharma, Judith K Amorosa, Veronica Arteaga, Maya Galperin-Aizenberg, Ritu R Gill, Myrna CB Godoy, Stephen Hobbs, Jean Jeudy, Archana Laroia, Palmi N Shah, Dharshan Vummidi, Kavitha Yaddanapudi, Anouk Stein: Augmenting the National Institutes of Health chest radiograph dataset with expert annotations of possible pneumonia Radiology: Artificial Intelligence 1 (1): e180041,2019.

Jeffrey D. Rudie, MD, PhD; Xie Long, PhD; Wang Jiancong; Jeffrey Duda, PhD; Joshua Choi, MD; Raghav Mattay, MD; Po-Hao Chen, MD, MBA; R Nick Bryan, MD, PhD; Emmanuel Botzolakis, MD, PhD; Ilya Nasrallah, MD, PhD; Tessa Cook, MD, PhD, CIIP; Suyash Mohan, MD; James Gee, PhD;, Andreas M. Rauschecker, MD, PhD: Deep Learning and Bayesian Inference System for Automated Brain MR Diagnosis Performs at Level of Academic Neuroradiologists and Augments Resident Performance SIIM 2019 : 2019.

Andreas M. Rauschecker, MD, PhD; Long Xie, PhD; Wang Jiancong; Michael T. Duong; R. Nick Bryan, MD, PhD; Emmanuel Botzolakis, MD, PhD; Ilya Nasrallah, MD, PhD; Asha Kovalovich, MD; John Egan, MD; Tessa Cook, MD, PhD, CIIP; Suyash Mohan, MD; James Gee, PhD; Jeffrey D. Rudie, MD, PhD: Artificial Intelligence System Achieves Academic Neuroradiologist Level Diagnosis on Diseases of Cerebral Hemispheres SIIM 2019 : 2019.

Academic Contact Info

Hospital of University of Pennsylvania
Department of Radiology
1 Silverstein
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 662-3431
Patient appointments: 800-789-7366 (PENN)