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Samuel D. Swisher-McClure, MD, MSHP

Samuel D. Swisher-McClure, MD, MSHP Physician

Assistant Professor of Radiation Oncology at the Hospital of the University of Pennsylvania

Dr. Swisher-McClure is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Radiation Oncology

Programs & Centers:

Board Certification:

  • Radiation Oncology, 2013

Clinical Expertise:

  • Head and Neck Cancer
  • Image-Guided Radiation Therapy (IGRT)
  • Laryngeal Cancer
  • Lung Cancer
  • Mouth Cancer (Oral Cancer)
  • Nasal Cavity and Paranasal Sinus Cancer
  • Nasopharyngeal Cancer
  • Orbital Tumors
  • Oropharyngeal Cancer
  • Proton Therapy
  • Radiation Oncology - Head/Neck
  • Radiation Oncology - Lung
  • Salivary Gland Cancer
  • Sinus Cancer
  • Stereotactic Radiation Therapy (SRT)

Description of Clinical Expertise

Dr. Swisher-McClure's clinical practice is focused on the multidisciplinary management of patients with thoracic and head and neck malignancies.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: West Virginia University School of Medicine
Residency: Hospital of the University of Pennsylvania


American Society for Radiation Oncology, National American Society of Clinical Oncology, National

Hospital Affiliation

Dr. Swisher-McClure is employed by Penn Medicine.

Hospital Privileges:

  • Chester County Hospital: Has privileges to treat patients in the hospital.
  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Samuel Swisher-McClure, MD MSHP is an Assistant Professor of Radiation Oncology at the University of Pennsylvania. He serves as the residency program director for the Department of Radiation Oncology and directly oversees the clinical training of 16 residents within the department. He conducts oncology related health services research, and previously completed a Masters degree in Health Policy Research at the University of Pennsylvania.

Selected Publications:

Frick Melissa A, Kao Gary D, Aguarin Louise, Chinniah Chimbu, Swisher-McClure Samuel, Berman Abigail T, Levin William P, Cengel Keith A, DeCesaris Cristina, Hahn Stephen M, Dorsey Jay F, Simone Charles B: Circulating Tumor Cell Assessment in Presumed Early Stage Non-Small Cell Lung Cancer Patients Treated with Stereotactic Body Radiation Therapy: A Prospective Pilot Study. International journal of radiation oncology, biology, physics 102 (3): 536-542,2018.

Jahangiri Pegah, Pournazari Kamyar, Torigian Drew A, Werner Thomas J, Swisher-McClure Samuel, Simone Charles B, Alavi Abass: A prospective study of the feasibility of FDG-PET/CT imaging to quantify radiation-induced lung inflammation in locally advanced non-small cell lung cancer patients receiving proton or photon radiotherapy. European journal of nuclear medicine and molecular imaging : 2018.

Grover Surbhi, Desir Fidel, Jing Yuezhou, Bhatia Rohini K, Trifiletti Daniel M, Swisher-McClure Samuel, Kobie Julie, Moore Richard D, Rabkin Charles S, Silverberg Michael J, Salters Kate, Mathews W Christopher, Gill M John, Thorne Jennifer E, Castilho Jessica, Kitahata Mari M, Justice Amy, Horberg Michael A, Achenbach Chad J, Mayor Angel, Althoff Keri N: Reduced cancer survival among adults with HIV and an AIDS-defining illnesses despite no difference in cancer stage at diagnosis. Journal of acquired immune deficiency syndromes (1999) : 2018.

Nead Kevin T, Swisher-McClure Samuel: Utilization of hypofractionated radiation therapy in older glioblastoma patients. Journal of geriatric oncology : 2018.

Guttmann David M, Kobie Julie, Grover Surbhi, Lin Alexander, Lukens John N, Mitra Nandita, Rhodes Karin V, Feng Weiwei, Swisher-McClure Samuel: National disparities in treatment package time for resected locally advanced head and neck cancer and impact on overall survival. Head & neck : 2018.

Kufta Kenneth, Forman Michael, Swisher-McClure Samuel, Sollecito Thomas P, Panchal Neeraj: Pre-Radiation dental considerations and management for head and neck cancer patients. Oral oncology 76 : 42-51,2018.

Guttmann David M, Mitra Nandita, Metz James M, Plastaras John, Feng Weiwei, Swisher-McClure Samuel: Neoadjuvant chemoradiation is associated with improved overall survival in older patients with esophageal cancer. Journal of geriatric oncology : 2017.

Routman David M, Funk Ryan K, Tangsriwong Kanograt, Lin Alexander, Keeney Michael G, García Joaquín J, Zarka Matthew A, Lewis Jason T, Stoddard David G, Moore Eric J, Day Courtney N, Zhai Qihui, Price Katharine A, Lukens John N, Swisher-McClure Samuel, Weinstein Gregory S, O'Malley Bert W, Foote Robert L, Ma Daniel J: Relapse Rates With Surgery Alone in Human Papillomavirus-Related Intermediate- and High-Risk Group Oropharynx Squamous Cell Cancer: A Multi-Institutional Review. International journal of radiation oncology, biology, physics : 2017.

Nead Kevin T, Swisher-McClure Samuel, Shah Nigam H: Androgen Deprivation Therapy and Subsequent Dementia-Reply. JAMA oncology : 2017.

Trifiletti Daniel M, Smith Andrew, Mitra Nandita, Grover Surbhi, Lukens John N, Cohen Roger B, Read Paul, Mendenhall William M, Lin Alexander, Swisher-McClure Samuel: Beyond Positive Margins and Extracapsular Extension: Evaluating the Utilization and Clinical Impact of Postoperative Chemoradiotherapy in Resected Locally Advanced Head and Neck Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 35 (14): 1550-1560,2017.

Academic Contact Info

3400 Civic Center Boulevard, TRC2 West
Department of Radiation Oncology

Philadelphia, PA 19104
Phone: (215) 220-9460
Patient appointments: 800-789-7366 (PENN)