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Saif Anwaruddin, MD

Saif Anwaruddin, MD Physician

Co-Director, Transcatheter Valve Program
Assistant Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Anwaruddin is a Penn Medicine employed physician.

Clinical Specialties


  • Cardiology

Programs & Centers:

Board Certification:

  • Cardiovascular Disease, 2008
  • Interventional Cardiology, 2009

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Massachusetts
Residency: Massachusetts General Hospital
Fellowship: Clinical Clinic Foundation
Fellowship: Cleveland Clinic Foundation


American College of Cardiology, National American College of Cardiology, National American College of Physicians, National Massachusetts Medical Society, Local Society for Cardiac Angiography and Interventions, International Worcester District Medical Society, Local

Hospital Affiliation

Dr. Anwaruddin is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Selected Publications:

Shreenivas S, Lilly S, Desai ND, Farooki A, Cheung AT, Acker MA, Herrmann HC, Anwaruddin S: Percutaneous Closure of an Aortic Pseudoaneurysm due to Saphenous Vein Graft Dehiscence with an Amplatzer Vascular Plug. JACC Cardiovasc Interv 6 (10): 1103-4,2013.

Anwaruddin S: Transcatheter Aortic Valve Replacement (TAVR). SCAI Interventional Cardiology Board Review Book. (Section IX; Chapter 41) Lippincott : 2013.

Lilly SM, Rome J, Anwaruddin S, Shreenivas S, Desai N, Silvestry FE, Herrmann HC, Fassa A, Himbert D, Brochet E, Labbé JP, Depoix JP, Hvass U, Vahanian A, Holoshitz N, Kenny D, Hijazi ZM: How should I treat prosthetic tricuspid stenosis in an extreme surgical risk patient? EuroIntervention 9 (3): 407-9,2013.

Hahn RT, Pibarot P, Stewart WJ, Weissman NJ, Gopalakrishnan D, Keane MG, Anwaruddin S, Wang Z, Bilsker M, Lindman BR, Herrmann HC, Kodali SK, Makkar R, Thourani VH, Svensson LG, Akin JJ, Anderson WN, Leon MB, Douglas PS: Comparison of transcatheter and surgical aortic valve replacement in severe aortic stenosis: a longitudinal study of echocardiography parameters in cohort A of the PARTNER trial (placement of aortic transcatheter valves). J Am Coll Cardiol 61 (25): 2514-21,2013.

Shreenivas S,Anwaruddin S: Management of Complications During Saphenous Vein Graft Interventions in Saphenous Vein Graft Lesions and Thrombectomy for Acute Myocardial Infarction Elsevier 2 (2): 339-346,2013.

Anwaruddin S, Martin JM, Stephens JC, Askari AT: Cardiovascular Hemodynamics: An Introductory Guide Erratum Springer : E1,2013.

Bortnick AE, Gordon E, Gutsche J, Anwaruddin S, Szeto W, Desai N, Vallabhajoyusla P, Bavaria JE, Herrmann HC: Percutaneous Closure of a Left Ventricular Pseudoaneurysm After Sapien XT Transapical Transcatheter Aortic Valve Replacement. JACC Cardiovasc Interv 5 (12): e37-8,2012.

Richman S, Gee AP, McKenna DH, Traverse JH, Henry TD, Fisk D, Pepine CJ, Bloom J, Willerson JT, Prater K, Zhao D, Koc JR, Anwaruddin S, Taylor DA, Cogle CR, Moye LA, Simari RD, Skarlatos SI: Factors Affecting the Turnaround Time for Manufacturing, Testing and Release of Cellular Therapy Products Prepared at Multiple Sites in Support of Multicenter Cardiovascular Regenerative Medicine Protocols: A Cardiovascular Cell Therapy Research Network (CCTRN) Study. Transfusion 52 (10): 2225-33,2012.

Perin, EC, Willerson JT, Pepine CJ, Henry TD, Ellis SG, Zhao DX, Silva GV, Lai D, Thomas JD, Kronenberg MW, Martin AD, Anderson RD, Traverse JH, Penn MS, Anwaruddin S, Hatzopoulos, AK, Gee,AP, Taylor DA, Cogle CR, Smith, D, Westbrook L, Chen J, Handberg E, Olson RE, Geither C, Bowman S, Francescon J, Baraniuk S, Piller LB, Simpson LM, Loghin C, Aguilar D, Richman S, Zierold, C, Bettencourt J, Sayre SL, Vojvodic,RW, Skarlatos, SI, Gordon DJ, Ebert RF, Kwak M, Moyé LA, Simari RD: The Effect of Transendocardial Delivery of Autologous Bone Marrow Mononuclear Cells on Functional Capacity, Left Ventricular Function, and Perfusion in Chronic Ischemic Heart Failure: The FOCUS-CCTRN Trial JAMA 307 (16): 1717-26,2012.

Bortnick A, Selzer F, Anwaruddin S, Epps KC, Marroquin OC, Srinivas VS, Holper EM, Wilensky RL: Evaluation of Percutaneous Coronary Intervention: Outcomes from the 5 Year Follow-up from the NHLBI Dynamic Registry. J Am Coll Cardiol 59 (13s1): E75,2012.

Academic Contact Info

Hospital of the University of Pennsylvania
9036 Gates Pavilion
3400 Spruce Street

Philadelphia, PA 19104
Phone: (215) 615-4333
Patient appointments: 800-789-PENN (7366)