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Saif Anwaruddin, MD

Saif Anwaruddin, MD Physician

Co-Director, Transcatheter Valve Program Assistant Professor of Medicine in Surgery Assistant Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Anwaruddin is employed by Penn Medicine.

About Dr. Saif Anwaruddin

Recognized by America's Top Doctors 2015 - 2017

Recognized in Philadelphia magazine's annual Top Docs issues for 2018 and 2019

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties

Specialty:

  • Cardiology

Programs & Centers:

Board Certification:

  • Cardiovascular Disease, 2008
  • Interventional Cardiology, 2009

Clinical Expertise:

  • Abnormal Coronary Angiography
  • Abnormal Stress Test
  • Acute Bacterial Endocarditis
  • Alcohol Septal Ablation
  • Angioplasty
  • Aortic Stenosis
  • Aortic Valve Disorders
  • Aortic Valve Regurgitation
  • Atherectomy
  • Atherosclerosis (Arteriosclerosis)
  • Atherosclerosis of the Aorta
  • Athlete's Heart
  • Atrial Septal Defect (ASD)
  • Atrial Septal Defect Repair
  • Balloon Aortic Valvuloplasty
  • Balloon Mitral Valvuloplasty
  • Bicuspid Aortic Valve
  • Bicuspid Valve Repair
  • Cardiac Arrest
  • Cardiogenic Shock
  • Cardiomyopathy
  • Catheter Angiography
  • Chest Pain
  • Chest Pain (Angina)
  • Chronic Total Occlusion
  • Congenital Insufficiency of the Aortic Valve
  • Congenital Mitral Valve Regurgitation
  • Congenital Pulmonary Valve Atresia
  • Congenital Stenosis of the Aortic Valve
  • Congenital Stenosis of the Mitral Valve
  • Congenital Stenosis of the Pulmonary Valve
  • Congenital Subaortic Stenosis
  • Congenital Tricuspid Stenosis
  • Congestive Heart Failure
  • Coronary Angioplasty
  • Coronary Artery Anomaly
  • Coronary Artery Disease
  • Coronary Artery Fistula
  • Coronary Stenting
  • Directional Atherectomy
  • Edwards Sapien Transcatheter Aortic Heart Valve
  • Embolic-Protection Devices
  • Endocarditis
  • Exercise Intolerance
  • Femoral Artery Angioplasty
  • Fractional Flow Reserve
  • Heart Attack (Myocardial Infarction)
  • Heart Biopsy
  • Hypertrophic Cardiomyopathy
  • Idiopathic Hypertrophic Subaortic Stenosis
  • Ischemic Cardiomyopathy
  • Laser Atherectomy
  • Marfan Syndrome
  • Maternal Valvular Disease
  • Mesenteric Artery Stenting
  • Minimally Invasive Aortic Valve Replacement
  • Minimally Invasive Closure of Atrial Septal Defect
  • Minimally Invasive Mitral Valve Surgery
  • Mitral Regurgitation
  • Mitral Stenosis
  • Mitral Valve Disorders
  • Mitral Valve Prolapse
  • Mitral Valve Regurgitation
  • Papillary Muscle Disease
  • Paravalvular Leak
  • Paravalvular Leak Repair
  • Patent Ductus Arteriosus
  • Patent Foramen Ovale Closure
  • Percutaneous Atrial Septal Defect Closure
  • Percutaneous Mitral Valve Repair
  • Percutaneous Valvuloplasty
  • Peripheral Angiography
  • Peripheral Artery Angioplasty
  • Peripheral Vascular Diseases
  • Prinzmetals Angina
  • Prosthetic Heart Valves
  • Pulmonary Arteriovenous Malformation
  • Pulmonary Artery Coarctation and Atresia
  • Pulmonary Artery Stenosis
  • Pulmonary Valve Disorders
  • Pulmonary Valve Insufficiency
  • Pulmonary Valve Stenosis (PVS)
  • Refractory Angina
  • Replacement of Heart Valve
  • Restrictive Cardiomyopathy
  • Rheumatic Aortic Regurgitation
  • Rheumatic Aortic Stenosis
  • Rheumatic Diseases of Pulmonary Valve
  • Rheumatic Fever
  • Rheumatic Heart Disease
  • Rheumatic Heart Failure
  • Rheumatic Mitral Regurgitation
  • Rheumatic Mitral Stenosis
  • Right Heart Failure
  • Right Ventricular Hypertrophy
  • Rotational Atherectomy
  • Stenotic Valve Diseases
  • Subaortic Stenosis
  • Subvalvular Pulmonic Stenosis
  • Superior Mesenteric Artery Stenting
  • Thrombectomy
  • Thrombosis of the Iliac Artery
  • Transcatheter Aortic Valve Replacement (TAVR)
  • Transradial Catheterization
  • Transradial Coronary Angioplasty
  • Tricuspid Atresia
  • Tricuspid Regurgitation
  • Tricuspid Stenosis
  • Tricuspid Valve Disease
  • Ultrasound
  • Unstable Angina
  • Valve Stenosis
  • Ventricular Aneurysm
  • Ventricular Septal Defect Repair
  • Watchman Device Implantation
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Massachusetts
Residency: Massachusetts General Hospital
Fellowship: Cleveland Clinic Foundation

Memberships

American College of Cardiology, National Massachusetts Medical Society, Local Society for Cardiac Angiography and Intervention (SCAI), National

Hospital Affiliation

Dr. Anwaruddin is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

Transcatheter aortic valve replacement for aortic insufficiency in LVAD patients

Soluble FMS like Tyrosine Kinase 1 in Cardiovascular and Renal disease

Evaluation of Novel Transcatheter Mitral Valve Repair and Replacement Technology

Stroke, TAVR and Embolic Protection

Selected Publications:

Anwaruddin S and Saybolt MD: Improving Quality and Outcomes in TAVR: Turning Up the Volume? J Am Coll Cardiol 73 (4): 441-43,2019.

Tang GHL, Zaid S, George I, Khalique OK, Abramowitz Y, Maeno Y, Makkar RR, Jilaihawi H, Kamioka N, Thourani VH, Babaliaros V, Webb JG, Htun NM, Attinger-Toller A, Ahmad H, Kaple R, Sharma K, Kozina JA, Kaneko T, Shah P, Hirji SA, Desai ND, Anwaruddin S, Jagasia D, Herrmann HC, Basra SS, Szerlip MA, Mack MJ, Mathur M, Tan CW, Don CW, Sharma R, Gafoor S, Zhang M, Kapadia SR, Mick SL, Krishnaswamy A, Amoroso N, Salemi A, Wong SC, Kini AS, Rodes-Cabau J, Leon MB, Kodali SK: Impact of Aortic Root Anatomy and Geometry on Paravalvular Leak in Transcatheter Aortic Valve Replacement With Extremely Large Annuli Using the Edwards SAPIEN 3 Valve. JACC Cardiovasc Interv 11 (14): 1377-1387,2018.

Mangels DR, Siki M, Menon R, Bavaria JE, Anwaruddin S, Giri J, Desai N, Szeto WY, Vallabhajosyula P, Herrmann HC: Hemodynamic Effects of Valve Asymmetry in Sapien 3 Transcatheter Aortic Valves. J Invasive Cardiol 30 (4): 138-143,2018.

McCarthy FH, Vemulapalli S, Li Z, Thourani V, Matsouaka RA, Desai ND, Kirtane A, Anwaruddin S, Williams ML, Giri J, Vallabhajosyula P, Li RH, Herrmann HC, Bavaria JE, Szeto WY: Association of Tricuspid Regurgitation With Transcatheter Aortic Valve Replacement Outcomes: A Report From The Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry. Ann Thorac Surg 105 (4): 1121-1128,2018.

Fiorilli PN, Anwaruddin S, Zhou E, Shah R: Catheterization Laboratory: Structural Heart Disease, Devices, and Transcatheter Aortic Valve Replacement. Anesthesiol Clin 35 (4): 627-639,2017.

Rene AG, Desai N, Wald J, Rame JE, Frogel JK Anwaruddin S: Transfemoral transcatheter aortic valve replacement with a self-expanding valve for severe aortic regurgitation in a patient with left ventricular assist device. J Card Surg 32 (11): 741-74,2017.

Mangels DR, Siki M, Menon R, Bavaria JE, Anwaruddin S, Giri J, Desai N, Szeto WY, Vallabhajosyula P, Herrmann HC: Hemodynamci Effects of Valve Asymmetry in Sapien 3 Transcatheter Aortic Valves. J Am Coll Cardiol : Abstract Supplement,2017.

Anwaruddin S: Self-Expanding TAVR for Treatment of Aortic Insufficiency: An Analysis of the STS/ACC TVT Registry. J Am Coll Cardiol : Abstract Supplement,2017.

McCarthy FH, Spragan DD, Savino D, Dibble T, Hoedt AC, McDermott KM, Bavaria JE, Herrmann HC, Anwaruddin S, Giri J, Szeto WY, Groeneveld PW, Desai ND: Outcomes, readmissions, and costs in transfemoral and alterative access transcatheter aortic valve replacement in the US Medicare population. J Thorac Cardiovasc Surg 154 (4): 1224-1232,2017.

Taneja I, Reddy B, Damhorst G, Dave Zhao S, Hassan U, Price Z, Jensen T, Ghonge T, Patel M, Wachspress S, Winter J, Rappleye M, Smith G, Healey R, Ajmal M, Khan M, Patel J, Rawal H, Sarwar R, Soni S, Anwaruddin S, Davis B, Kumar J, White K, Bashir R, Zhu R: Combining Biomarkers with EMR Data to Identify Patients in Different Phases of Sepsis. Sci Rep 7 (1): 2017.

Academic Contact Info

Hospital of the University of Pennsylvania
Perelman Center for Advanced Medicine
11th Floor - South Tower
34th Civic Center Boulevard

Philadelphia, PA 19104
Phone: (215) 615-4333
Patient appointments: 800-789-7366 (PENN)