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Rotonya M. Carr, MD

Rotonya M. Carr, MD Physician

Director, Liver Metabolism and Fatty Liver Program Assistant Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Carr is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Gastroenterology

Programs & Centers:

Board Certification:

  • Gastroenterology, 2011

Clinical Expertise:

  • Abdominal Bloating
  • Abdominal Disorders
  • Abdominal Distention
  • Abdominal Pain
  • Abnormal Liver Function
  • Abnormal Stool
  • Acute Pancreatitis
  • Alcoholic Liver Disease
  • Altered Bowel Habits
  • Anal Pain
  • Anal Spasm
  • Annular Pancreas
  • Anorexia
  • Autoimmune Enteropathy
  • Autoimmune Hepatitis
  • Barrett's Esophagus
  • Benign Neoplasm of Colon
  • Blood in Stool
  • Bowel Disorders
  • Bowel Dysmotility
  • Bowel incontinence (Fecal Incontinence)
  • Bright Red Blood in Rectum
  • C. Difficile (Clostridium Difficile Diarrhea)
  • Celiac Disease (Celiac Sprue)
  • Cholangitis
  • Cholecystitis
  • Cholelithiasis
  • Cholestasis
  • Chronic Diarrhea
  • Chronic Pancreatitis
  • Colitis
  • Collagenous Colitis
  • Colonic Inertia
  • Colonic Polyps
  • Colonoscopy
  • Constipation
  • Crigler Najjar Syndrome
  • Crohn's Disease
  • Cyclic Vomiting Syndrome
  • Difficulty Swallowing (Dysphagia)
  • Digestive Conditions
  • Diverticular Disease
  • Diverticulitis (Colonic Diverticulitis)
  • Duodenal Ulcer
  • Duodenitis
  • Dyspepsia
  • Early Satiety
  • Eosinophilic Colitis
  • Eosinophilic Enteritis
  • Eosinophilic Esophagitis (EoE)
  • Eosinophilic Gastritis
  • Epigastric Pain
  • Eructation
  • Esophageal Achalasia
  • Esophageal Disorders
  • Esophageal Motility Disorders
  • Esophageal Spasm
  • Esophageal Stricture
  • Esophageal Thickening
  • Esophageal Ulcer
  • Esophageal Varices
  • Esophagitis
  • Esophagus Tumors
  • Fatty Liver Diseases
  • Fecal Impaction
  • Feeding Tube Management
  • Flatulence
  • Focal Nodular Hyperplasia
  • Gallbladder Disorders
  • Gallbladder Polyp
  • Gastric Anomaly
  • Gastric Ulcer
  • Gastritis
  • Gastroenteritis
  • Gastroesophageal Reflux Disease (GERD)
  • Gastrointestinal Amyloid
  • Gastrointestinal Bleeding
  • Gastrointestinal Cancer Screening
  • Gastrojejunal Ulcer
  • Gastroparesis
  • Gastroscopy
  • Giardiasis
  • Gluten Sensitivity
  • H. Pylori Infection
  • Hematemesis
  • Hemochromatosis
  • Hepatitis
  • Hepatitis B
  • Hepatitis C
  • Hepatomegaly
  • Hereditary Nonpolyposis Colorectal Cancer
  • Hiatal Hernia
  • Ileitis
  • Inflammatory Bowel Disease (IBD)
  • Intestinal Obstruction
  • Intestinal Pseudo-Obstruction
  • Intractable Vomiting
  • Irritable Bowel Syndrome
  • Ischemic Colitis
  • Jaundice
  • Lactose Intolerance
  • Liver Cirrhosis
  • Liver Diseases
  • Liver Mass
  • Lymphocytic Colitis
  • Malabsorption
  • Melena
  • Microscopic Colitis
  • Motility Disorders
  • Nausea
  • Non-Alcoholic Fatty Liver Disease
  • Obstipation
  • Obstructive Jaundice
  • Odynophagia
  • Pancreas Divisum
  • Pancreatic Cyst
  • Pancreatic Insufficiency
  • Pancreatic Pseudocyst
  • Pancreaticobiliary Disease
  • Pancreatitis
  • Peptic Ulcer Disease (Stomach Ulcers)
  • Peritonitis
  • Pernicious Anemia
  • Peutz-Jeghers Syndrome
  • Polyposis Syndrome
  • Portal Hypertension
  • Portal Hypertensive Gastropathy
  • Postprandial Diarrhea
  • Proctitis
  • Proctosigmoidoscopy
  • Rectal Bleeding
  • Rectal Disorders
  • Short Bowel Syndrome (Short Gut Syndrome)
  • Sigmoidoscopy
  • Small Bowel Disease
  • Steatorrhea
  • Stomach Cramps
  • Stomach Disorders
  • Swallowing Disorders
  • Toxic Liver Injury
  • Ulcerative Colitis
  • Upper GI Endoscopy
  • Vomiting
  • Whipple's Disease
  • Wilson's Disease
  • Zenker's Diverticulum
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Weill Medical College of Cornell University
Residency: Massachusetts General Hospital
Fellowship: Hospital of the University of Pennsylvania


American Association for the Study of Liver Diseases, National American Gastroenterological Association External Advisory Board for the AGA FORWARD Program (an R25 grant to promote the growth and retention of underrepresented minority academic GIs, obtained during my tenure as Chair of the Diversity Committee), National American Gastroenterology Association, National American Medical Association, National European Association for the Study of Liver, International National Institutes of Health, NIAAA, Study Section, National NIH/NIDDK/Network of Minority Health Research Investigators, a national network of minority researchers with NIDDK-related research; sponsored by NIDDK, National Research Society on Alcoholism, National Robert Wood Johnson, Harold Amos Medical Faculty Development Program, National

Hospital Affiliation

Dr. Carr is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Radnor: Has privileges to perform procedures.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Translational and basic science research in liver metabolic diseases including non-alcoholic and alcoholic fatty liver disease, focusing on the pathologic role of lipids and lipid associated proteins.

Selected Publications:

Williams B, Correnti J, Oranu A, Lin A, Scott V, Annoh M, Beck J, Furth E, Mitchell V, Senkal C, Obeid L, Carr RM: A novel role for ceramide synthase 6 in mouse and human alcoholic steatosis FASEB Journal : 2017.

Carr, RM: In NAFLD, you are what you eat, not simply how much you eat Cellular and Molecular Gastroenterology and Hepatology 4 (2): 301–302,2017.

Falk, G; Ginsberg, G; Katzka, D; Carr, RM; Hamilton, K; Wu, G: Presentation of the Julius M. Friedenwald Medal to Anil K. Rustgi Gastroenterology : 2017.

Shubert, Rachel: New Study: Unsaturated Fat Associated with Fatty Liver Disease CMGH researchers report on the role of macronutrients in the development of metabolically unhealthy obesity. GastroPress : 2017.

Carr RM, Dhir R, Mahadev K, Comerford M, Chalasani NP, Ahima RS: Perilipin Staining Distinguishes Between Steatosis and Nonalcoholic Steatohepatitis in Adults and Children Clin Gastroenterol Hepatol 15 (1): 145-47,2017.

Carr RM, *, Patel A *, Bownik H, Oranu A, Kerner C, Praestgaard A, Forde KA, K. Reddy KR, Lichtenstein GR, *Co-first author: Intestinal Inflammation Does Not Predict Non-alcoholic fatty liver disease Severity in Inflammatory Bowel Disease Patients Digestive Diseases and Sciences 62 (5): 1354-1361.,2017.

Amanke Oranu, MD, Victoria Mitchell, Victoria Scott, Bianca Williams, Jason Correnti, Ph.D., and Rotonya Carr, M.D.: Chronic alcohol consumption upregulates ceramide synthase 6 in hepatic lipid droplets and zone 3 hepatocytes of mice and humans AASLD 2017 : 2017.

Alexis Ogdie, Sungat K. Grewal, Megan H. Noe, Daniel B. Shin, Junko Takeshita, Zelma C. Chiesa Fuxench, Rotonya M. Carr, and Joel M. Gelfand: Risk of incident liver disease in patients with psoriasis, psoriatic arthritis, and rheumatoid arthritis: a population-based study. Journal of Investigative Dermatology : 2017.

Quezada, et al.: Diversity in GI Training: A Timely Goal The New Gastroenterologist : 2017.

Roland Li, MD; Marina Serper, MD, MS; Vandana Khungar, MD, MSc; Amy Praestgaard, MS and Rotonya M. Carr, MD: Impact of race/ethnicity and primary admission diagnosis on readmission and mortality rates among patients hospitalized with hepatic encephalopathy AASLD 2017 : 2017.

Oranu, A; Williams, B; Correnti, J; Scott, V; Mitchell, V.; and Carr, RM: Absence of Perilipin 2 prevents the increase of long-chain ceramides in the lipid droplet fractions of alcohol-fed mice Gordon Research Conference : 2017.

Oranu, A; Lin, A.; Williams, B; Correnti, J; Beck, J; and Carr, RM: Absence of Perilipin 2 prevents the increase of long-chain ceramides in the lipid droplet fractions of alcohol-fed mice Hepatology 64 (S1): 2016.

Williams, B; Correnti, J, Oranu, A; Lin, A; Beck, J. and Carr, RM: Ceramide Synthase May Regulate Hepatic Perilipin 2 and Lipid Metabolism in Experimental Alcoholic Steatosis FASEB Lipid Droplets: Dynamic Organelles in Metabolism and Beyond Conference : 2016.

Carr, RM; Oranu, A; Khungar, V.: Non-alcoholic fatty liver disease: Pathogenesis and Current Management Clinics in Gastroenterology 45 (4): 2016.

Williams B, Correnti J, Carr RM.: Ceramide Synthase May Regulate Hepatic Perilipin 2 and Lipid Metabolism in Experimental Alcoholic Steatosis AASLD Conference : 2015.

Kupfer SS, Carr RM, Carethers J: Reducing colorectal cancer risk among African-Americans Gastroenterology 149 (6): 1302-4,2015.

Carr, RM and Ahima RS.: Pathogenesis of Lipid Droplet Proteins in Liver Diseases Experimental Cell Research 340(2):187-92. : 2016.

Correnti, J; Williams, B; Gottshall, L; and Carr, RM.: Oleate, palmitate and C2 ceramide differentially impact lipid oxidation and trafficking in alcohol-treated human hepatoma cells Gordon conference : 2015.

Carr, RM, Correnti, J: Insulin resistance in clinical and experimental alcoholic liver disease Ann N Y Acad Sci 1353 : 1-20,2015.

Carr, RM and Reid, Andrea.: FXR agonists as Therapeutic Agents for Non-alcoholic Fatty Liver Disease Current Atherosclerosis Reports 17 (4): 2015.

Roland Li, Ann Tierney, and Rotonya Carr: The Impact of Peri-Discharge Interventions on 30-day Readmission and 90-day Mortality Rates for Patients Admitted with Hepatic Encephalopathy ACG National Meeting 2014 : 2014.

Carr RM, Peralta G, Yin X, Ahima RS: Absence of Perilipin 2 Prevents Hepatic Steatosis, Glucose Intolerance and Ceramide Accumulation in Alcohol-fed Mice PLoS One : 2014.

Rotonya Carr: Understanding the pathogenesis of insulin resistance in non-alcoholic and alcoholic liver diseases JSM Gastroenterology and Hepatology : 2013.

Carr RM, Patel A, Kerner C, Tierney A, Forde K, and Lichtenstein G.: Metabolic syndrome, but not IBD severity, increases risk of NAFLD severity in patients with dual diagnosis of IBD and NAFLD American Association for the Study of Liver Diseases (AASLD) : 2013.

McConnell R, Carr RM.: Headache with Hematochezia: A Case of Sumatriptan-Induced Ischemic Colitis Digestive Disease Week : 2013.

Carr RM, Patel A, Kerner C, Tierney A, Forde K, and Lichtenstein G.: Metabolic syndrome and IBD severity may increase risk of NAFLD Digestive Disease Week : 2013.

Carr RM, Dhir R, Yin X, Agarwal B, Ahima RS: Temporal effects of ethanol consumption on energy homeostasis, hepatic steatosis and insulin sensitivity in mice Alcohol Clin Exp Res : 2013.

Carr RM, Kalyankar M, Dhir R, Comerford M, Chalasani N, and Ahima RS: Differential expression of PLIN1 and PLIN2 in fatty liver diseases in adults and children IDOM : 2015.

Carr, Rotonya.: It’s lucky we found it. In E. Armstrong, M. Fischer, R Parsa-Parsi, and M. Wetzel (Eds.), The Health Care Dilemma: A Comparison of Health Care Systems in Three European Countries and the US (324-331). Singapore: World Scientific Publishing Co. The Health Care Dilemma: A Comparison of Health Care Systems in Three European Countries and the US (324-331). Singapore: World Scientific Publishing Co. : 2011.

Rotonya Carr and James Lewis.: "This study by Mathurin et al. not only calls into question the longstanding practice of..." Evaluation of: [Mathurin P et al. Early liver transplantation for severe alcoholic hepatitis. N Engl J Med. 2011 Nov 10; 365(19):1790-800; doi: 10.1056/NEJMoa1105703]. Faculty of 1000, 19 Dec 2011. Faculty of 1000 : 2011.

Carr RM, Patel R, Rao V, Graham M, Crooke R, and Ahima R: Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in diet-induced obese mice EASL : 2011.

Carr RM, Patel R, Rao V, Graham M, Crooke R, and Ahima R: Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice Am J Physiol Regul Integr Comp Physiol. 302 (8): R996-1003,2012.

Ahima R and Carr R: Alas! Ileal interposition surgery for diabetes prevention? Gastroenterology 138 (7): 2437-46,2010.

Carr RM, Mohrman L, Arelli V, Masters E: Update on Cause and Management of Catscratch Disease Infections in Medicine 25 (5): 242-250,2008.

Wolden-Hanson T, Mitton DR, McCants RL, Yellon SM, Wilkinson CW, Matsumoto AM, Rasmussen DD: Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat. Endocrinology 141 (2): 487-97,2000.

Carr, Rotonya McCants and Lynch, John P: At the crossroads in the management of gastroesophageal junction carcinomas-where do we go from here? Gastrointestinal cancer research : GCR 2 (5): 253-5,2008.

View all publications

Academic Contact Info

421 Curie Boulevard
907 Biomedical Research Building II/III

Philadelphia, PA 19104
Phone: (215) 349-8222
Patient appointments: 800-789-7366 (PENN)