Description of Research Expertise:
Translational and basic science research in liver metabolic diseases including non-alcoholic and alcoholic fatty liver disease, focusing on the pathologic role of lipids and lipid associated proteins.
Carr, RM and Reid: FXR agonists as Therapeutic Agents for Non-alcoholic Fatty Liver Disease Current Atherosclerosis Reports 17 (4): 2015.
Carr, RM, Correnti: Insulin resistance in clinical and experimental alcoholic liver disease Ann N Y Acad Sci 1353 : 1-20,2015.
Carr RM, Peralta G, Yin X: Absence of Perilipin 2 Prevents Hepatic Steatosis, Glucose Intolerance and Ceramide Accumulation in Alcohol-fed Mice PLoS One 9 (5): e97118,2014.
Roland Li, Ann Tierney: The Impact of Peri-Discharge Interventions on 30-day Readmission and 90-day Mortality Rates for Patients Admitted with Hepatic Encephalopathy ACG National Meeting 2014 : 2014.
Carr RM, Dhir R, Yin X, Agarwal B: Temporal effects of ethanol consumption on energy homeostasis, hepatic steatosis and insulin sensitivity in mice Alcohol Clin Exp Res 37 (7): 1091-9,2013.
Carr RM, Patel R, Rao V, Graham M, Crooke R: Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice Am J Physiol Regul Integr Comp Physiol. 302 (8): R996-1003,2012.
Carr RM, Patel A, Kerner C, Tierney A, Forde K: Metabolic syndrome and IBD severity may increase risk of NAFLD Digestive Disease Week
Understanding the pathogenesis of insulin resistance in non-alcoholic and alcoholic liver diseases JSM Gastroenterology and Hepatology 1 : 1002,2013.
Carr RM, Patel A, Kerner C, Tierney A, Forde K: Metabolic syndrome, but not IBD severity, increases risk of NAFLD severity in patients with dual diagnosis of IBD and NAFLD American Association for the Study of Liver Diseases (AASLD) : 2013.
McConnell R: Headache with Hematochezia: A Case of Sumatriptan-Induced Ischemic Colitis
Digestive Disease Week : 2013.
Carr RM, Kalyankar M, Dhir R,Comerford M, Chalasani N: Differential expression of PLIN1 and PLIN2 in fatty liver diseases in adults and children IDOM : 2015.
"This study by Mathurin et al. not only calls into question the longstanding practice of..." Evaluation of: [Mathurin P et al. Early liver transplantation for severe alcoholic hepatitis. N Engl J Med. 2011 Nov 10; 365(19):1790-800; doi: 10.1056/NEJMoa1105703]. Faculty of 1000, 19 Dec 2011. F1000.com/13408982 Faculty of 1000 : 2011.
Carr RM, Patel R, Rao V, Graham M, Crooke R: Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in diet-induced obese mice EASL : 2011.
Alas! Ileal interposition surgery for diabetes prevention? Gastroenterology 138 (7): 2437-46,2010.
Wolden-Hanson T, Mitton DR, McCants RL, Yellon SM, Wilkinson CW, Matsumoto AM: Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat. Endocrinology 141 (2): 487-97,2000.
Carr, Rotonya McCants and Lynch: At the crossroads in the management of gastroesophageal junction carcinomas-where do we go from here? Gastrointestinal cancer research : GCR 2 (5): 253-5,2008.
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