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Ramani Balu, MD, PhD

Ramani Balu, MD, PhD Physician

Assistant Professor of Neurosurgery Assistant Professor of Neurology at the Hospital of the University of Pennsylvania Assistant Professor of Anesthesiology and Critical Care

Languages spoken:

  • Tamil

Dr. Balu is employed by Penn Medicine.

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Clinical Specialties


  • Neurology

Programs & Centers:

Board Certification:

  • Neurology, 2012

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Case Western Reserve University School of Medicine
Residency: New York University - Bellevue Hospital
Residency: Hospital of the University of Pennsylvania


American Academy of Neurology, National Neurocritical Care Society, International Society of Critical Care Medicine, International

Hospital Affiliation

Dr. Balu is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Cellular Neurophysiology
Systems Neuroscience
Cerebrovascular Physiology
Optical Imaging
Fluorescence Microscopy
Patch Clamp Methods
Cerebral Autoregulation
Biology of the Neurovascular Unit
Synaptic Plasticity

Selected Publications:

Balu R, Kim J: Epileptiform activity following TBI predicts later epilepsy Neurocritical Care Society Podcast : 2018.

Balu R, Oddo M: Early prediction of coma recovery after cardiac arrest with blinded pupillometry Neurocritical Care Society Podcast : 2018.

Balu R, Siegler J: Teaching through clinical cases: the unconscious patient BrainWaves: A Neurology Podcast : 2018.

Balu R, Izzy S: Revisiting grade 3 diffuse axonal injury Neurocritical Care Society Podcast : 2018.

He L, Baker WB, Milej D, Kavuri VC, Mesquita RC, Busch DR, Abramson K, Jiang JY, Diop M, St Lawrence K, Amendolia O, Quattrone F, Balu R, Kofke WA, Yodh AG: Noninvasive continuous optical monitoring of absolute cerebral blood flow in critically ill adults. Neurophotonics 5 : 2018.

Parthasarathy AB, Gannon KP, Baker WB, Favilla C, Balu R, Kasner SE, Yodh AG, Detre JA, Mullen MT: Dynamic autoregulation of cerebral blood flow measured non-invasively with fast diffuse correlation spectroscopy Journal of Cerebral Blood Flow and Metabolism : 2018.

Balu R, McCracken L, Lancaster E, Graus F, Dalmau J, Titulaer MJ: A score that predicts one-year functional status in anti-NMDA receptor encephalitis patients Neurology : 2018.

Ellis CA, McClelland AC, Mohan S, Kuo E, Kasner SE, Zhang C, Khankhanian P, Balu R: Cerebrospinal fluid in posterior reversible encephalopathy syndrome: implications of elevated protein and pleocytosis The Neurohospitalist : 2018.

Busch DR, Balu R, Baker WB, Guo W, He L, Diop M, Milej D, Kavuri V, Amendolia O, St Lawrence K, Yodh AG, Kofke WA: Detection of brain hypoxia based on noninvasive monitoring of cerebral blood flow with diffuse correlation spectroscopy Neurocritical Care : 2018.

George G, Patel N, Jang C, Wheeler D, Yaddanapudi SS, Dissin J, Balu R, Rangaswami J: Proteinuria Predicts Resistance to Antiplatelet Therapy in Ischemic Stroke. Transl Stroke Res : 2018.

Academic Contact Info

Hospital of the University of Pennsylvania
Department of Neurology
3400 Spruce Street

Philadelphia, Pa 19104
Patient appointments: 800-789-7366 (PENN)