Selected Publications
Poleshko A*, Shah PP*, Gupta M*, Babu A, Morley MP, Manderfield LJ, Ifkovits JL, Calderon D, Aghajanian H, Sierra-Pagán JE, Sun Z, Wang Q, Li L, Dubois NC, Morrisey EE, Lazar MA, Smith CL, Epstein JA*, Jain R*: Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction Cell 171 (3): 573-587 e14,2017.
Aghajanian H, Cho YK, Rizer NW, Wang Q, Li L, Degenhardt K, Jain R: Pdgfralpha functions in endothelial-derived cells to regulate neural crest cells and the development of the great arteries Dis Model Mech 10 (9): 1101-1108,2017.
Ramjee V, Li D, Manderfield LJ, Liu F, Engleka KA, Aghajanian H, Rodell CB, Lu W, Ho V, Wang T, Li L, Singh A, Cibi DM, Burdick JA, Singh MK*, Jain R*, Epstein JA*: Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction J Clin Invest 127 (3): 899-911,2017.
Jain R*, Li D*, Gupta M, Manderfield LJ, Ifkovits JL, Wang Q, Liu F, Liu Y, Poleshko A, Padmanabhan A, Raum JC, Li L, Morrisey EE, Lu MM, Won KJ, Epstein JA: Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts Science 348 (6242): aaa6071,2015.
Loh KM, Chen A, Koh PW, Deng TZ, Sinha R, Tsai JM, Barkal AA, Shen KY, Jain R, Morganti RM, Shyh-Chang N, Fernhoff NB, George BM, Wernig G, Salomon REA, Chen Z, Vogel H, Epstein JA, Kundaje A, Talbot WS, Beachy PA, Ang LT, Weissman IL: Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types Cell 166 (2): 451-467,2016.
Kook H, Seo SB, Jain R: EZ Switch From EZH2 to EZH1: Histone Methylation Opens a Window of Cardiac Regeneration Circ Res 121 (2): 91-94,2017.
Jain R*, Barkauskas CE*, Takeda N, Bowie EJ, Aghajanian H, Wang Q, Padmanabhan A, Manderfield LJ, Gupta M, Li D, Li L, Trivedi CM, Hogan BL, Epstein JA: Plasticity of Hopx(+) type I alveolar cells to regenerate type II cells in the lung Nat Commun 6 : 6727,2015.
Takeda N*, Jain R*, Leboeuf MR, Padmanabhan A, Wang Q, Li L, Lu MM, Millar SE, Epstein JA: Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells Development 140 (8): 1655-64,2013.
Takeda N*, Jain R, LeBoeuf MR, Wang Q, Lu MM, Epstein JA.: Interconversion between intestinal stem cell populations in distinct niches Science 334 (6061): 1420-4,2011.
Jain R, Engleka KA, Rentschler SL, Manderfield LJ, Li L, Yuan L, Epstein JA: Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves J Clin Invest 121 (1): 422-30,2011.
High FA*, Jain R*, Stoller JZ, Antonucci NB, Lu MM, Loomes KM, Kaestner KH, Pear WS, Epstein JA: Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development J Clin Invest 119 (7): 1986-96,2009.
Ladurner AG, Inouye C, Jain R, Tjian R: Bromodomains mediate an acetyl-histone encoded antisilencing function at heterochromatin boundaries Mol Cell 11 (2): 365-76,2003.
View all publications
Academic Contact Information
09-102 Smilow Translational Research Building
3400 Civic Center Blvd
Philadelphia,
PA
19104
Phone: 215-746-5732