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Rabie M. Shanti, DMD, MD

Rabie M. Shanti, DMD, MD Physician

Assistant Professor of Oral and Maxillofacial Surgery Assistant Professor of Otorhinolaryngology/Head and Neck Surgery Assistant Professor of Otorhinolaryngology: Head and Neck Surgery

Dr. Shanti is employed by Penn Medicine.

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About Dr. Rabie M. Shanti

Dr. Rabie Shanti holds a dual appointment in the Department of Oral and Maxillofacial Surgery at Penn Dental Medicine, and the Department of Otorhinolaryngology/Head and Neck Surgery at Penn Medicine. Dr. Shanti’s clinical expertise includes the evaluation and surgical treatment of tumors of the head and neck, such as, benign tumors of the jaws (e.g., ameloblastoma, myxoma), malignant tumors of the jaws (e.g., osteosarcoma, chondrosarcoma), oral (mouth) cancer, and oropharyngeal (throat) cancer. In addition, Dr. Shanti frequently evaluates and manages advanced inflammatory conditions of the jaws, such as, osteoradionecrosis, and medication related osteonecrosis of the jaw. Dr. Shanti’s clinical practice is also devoted to microvascular reconstructive surgery of the head and neck following oncologic surgery, radiation injury, or trauma. 

In addition to his clinical activities, Dr. Shanti is involved in both clinical and translational research efforts that aim to enhance the efficacy of current treatment paradigms, as well as in the development of innovative treatment strategies for patients with benign and malignant tumors of the head and neck.

Clinical Specialties

Specialty:

  • Oral and Maxillofacial Surgery
  • Otorhinolaryngology

Programs & Centers:

Board Certification:

  • Oral and Maxillofacial Surgery, 2018

Clinical Expertise:

  • Acinic Cell Cancer
  • Adenocarcinoma of the Head and Neck
  • Adenoid Cystic Carcinoma
  • Ameloblastoma
  • Bone Graft Using Stem Cells
  • Cancer of the Hard/Soft Palate
  • Cancer of the Parotid
  • Chondrosarcoma
  • Clinical Trials
  • Ear and Temporal Bone Tumors
  • Face Cancer
  • Facial Tumor
  • Facial Tumors
  • Free Flap Neck
  • Glossectomy
  • Head and Neck Cancer
  • Head and Neck Sarcoma
  • Head and Neck Tumor
  • Head and Neck Tumor Reconstruction
  • Jaw Cancer
  • Leukoplakia
  • Liposarcoma
  • Malignant Neoplasm of Lip
  • Mandibulectomy
  • Maxillectomy
  • Melanoma on Face
  • Metastatic Squamous Neck Cancer with Occult Primary
  • Microvascular Flap Reconstruction
  • Mouth Cancer (Oral Cancer)
  • Myxoma
  • Nasal Cavity and Paranasal Sinus Cancer
  • Nasopharyngeal Cancer
  • Neck Cancer
  • Oropharyngeal Cancer
  • Osteomyelitis of the Craniofacial Skeleton
  • Osteonecrosis of the Jaw
  • Osteosarcoma
  • Pharyngeal Flap Surgery
  • Radical Neck Dissection
  • Salivary Gland Cancer
  • Sinus Cancer
  • Skull Base Tumors
  • Squamous Cell Carcinoma of the Skin of Lip
  • Throat Cancer
  • Throat Mass
  • Tongue Cancer
  • Tonsil Cancer
  • TransOral Robotic Surgery (TORS)
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Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Dental School: Harvard University
Residency: University of Medicine and Dentistry of New Jersey
Medical School: Rutgers New Jersey Medical School
Fellowship: Louisiana State University Health Sciences Center

Memberships

American Association for Dental Research, National American Association of Oral and Maxillofacial Surgeons, National American Dental Association, National American Medical Association, National International Association for Dental Research, International International Association of Oral and Maxillofacial Surgeons, International Pennsylvania Dental Association, Local Pennsylvania Medical Society, Local Philadelphia County Dental Society, Local Philadelphia County Medical Society, Local

Hospital Affiliation

Dr. Shanti is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

An extension of Dr. Shanti’s clinical interest in functional rehabilitation surgery through the utilization of reconstructive microsurgical techniques has been regenerative medicine. Dr. Shanti is currently investigating the potential of mesenchymal stem cells in tongue tissue engineering, as well as, the engineering of other orofacial tissues. This work is in collaboration with investigators from Penn Dental Medicine and Penn Medicine. Dr. Shanti also has a special interest in rare pathology of the head and neck, in investigating the pathogenesis of benign tumors and cysts of the jaw (i.e., ameloblastoma, odontogenic keratocyst, ossifying fibroma), and rare malignant tumors of the oral cavity (i.e., carcinosarcoma, osteosarcoma). Dr. Shanti has also been involved in investigative studies looking at complex infections of the head and neck (e.g., deep neck infections, osteomyelitis of the jaws) and for this work he was the co-recipient of the Daniel M. Laskin Award for the "most outstanding article published in the Journal of Oral and Maxillofacial Surgery in 2006."

GRANTS

Project title: Stromal cell-derived IL-6 promotes epithelial tumor stem-like cell generation by inducing epithelial-mesenchymal transition in ameloblastoma
Sponsoring Program: Oral & Maxillofacial Surgery Foundation Research Support Grant

Project title: Mesenchymal stromal cell-derived IL-6 facilitate EMT process and acquisition of stem-like cell properties in ameloblastoma epithelial cells
Sponsoring Program: Schoenleber Pilot Grant, School of Dental Medicine, University of Pennsylvania

Selected Publications:

Pratyusha Yalamanchi, William W Thomas, MD, Alan Workman, Karthik Rajasekaran, MD, Rabie M Shanti, DMD, MD, Ara C Chalian, MD, Jason G Newman, MD, Steven B Cannady, MD: Value of intensive care unit–based management for microvascular free flap reconstruction in head and neck surgery. Annual Meeting of the American Head and Neck Society : 2018.

Shang W, Zhang Q, Huang Y, Shanti R, Alawi F, Le D, Jiang C: Cellular plasticity-targeted therapy in head and neck cancers. Journal of Dental Research : 2018.

Shanti RM,O'Malley BW Jr.: Surgical management of oral cancer. Dental Clinics of North America 62 (2): 77-86,2018.

Mupparapu M,Shanti RM: Evaluation and staging of oral cancer. Dental Clinics of North America 62 (1): 47-58,2018.

Shanti RM, Smart RJ, Meram A, Kim D.: Porcine urinary bladder extracellular matrix for the salvage of fibula free flap skin paddle: technical note and description of a case. Craniomaxillofacial Trauma & Reconstruction 10 (4): 318-22,2017.

Thomas WW, Brant J, Chen J, Coblens O, Fischer JP, Newman JG, Chalian AA, Shanti RM, Cannady SB: Clinical factors associated with reoperation and prolonged length of stay in free tissue transfer to oncologic head and neck defects. JAMA Facial Plastic Surgery : 2017.

Jiang C, Zhang Q, Shanti RM, Shi S, Chang TH, Carrasco L, Alawi F, Le AD: Mesenchymal stromal cell-derived interleukin-6 promotes epithelial-mesenchymal transition and acquisition of epithelial stem-like cell properties in ameloblastoma epithelial cells. Stem Cells 35 (9): 2083-94,2017.

Gomez ED, Thakkar P, Rajasekaran K, Brody R, Shanti R, Newman JG, Cannady SB: Patient characteristics as predictors of postoperative complications in free flap reconstruction for head and neck cancer. American Head & Neck Society Annual Meeting : 2017.

Tanaka TI, Shanti RM: Coordinated care of a pregnant patient with nasopharyngeal carcinoma. American Academy of Oral Medicine Annual Conference : 2017.

Shanti RM, Kim DD, Ghali GE.: Melanoma. Oral and Maxillofacial Surgery: 3 Volume Set, 3rd Edition 2 : 690-706,2017.

Academic Contact Info

Perelman Center for Advanced Medicine
South Pavilion, 4th Floor
3400 Civic Center Boulevard

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)