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R. Nick Bryan, MD, PhD, FACR

R. Nick Bryan, MD, PhD, FACR Physician

Emeritus Professor of Radiology

Dr. Bryan is a Penn Medicine employed physician.

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About Dr. R. Nick Bryan

Recognized by Best Doctors in America 2003-2004, 2005-2006, 2007-2008, 2009-2010, 2011-2012, 2013-2014

Clinical Specialties


  • Radiology

Programs & Centers:

Board Certification:

  • Diagnostic Radiology, 1974
  • Neuroradiology, 1995

Description of Clinical Expertise


Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Texas
Residency: University of Texas Medical Branch at Galveston
Fellowship: University of Texas Medical Branch at Galveston
Fellowship: NewYork-Presbyterian/Columbia University Medical Center


American Association for the Advancement of Science, National American College of Radiology, National American Heart Association - Stroke Council, National American Society for Neuroscience, National American Society of Head & Neck Radiology, National American Society of Neuroradiology, National Association of University Radiologists, National European Radiology Association & Congress, International International Society of Magnetic Resonance in Medicine, International Pennsylvania Radiological Society, Local Radiologic Society of North America (RSNA), National Radiological Society of North America Research & Education Foundation, International Radiological Society of North America, International The College of Physicians of Philadelphia, Local World Federation of Neuroradiological Societies, International

Hospital Affiliation

Dr. Bryan is a Penn Medicine employed physician.

Hospital Privileges:

  • Chester County Hospital: Has privileges to treat patients in the hospital.
  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Cerebral MRI findings and cognitive functioning; applications of perfusion MRI for neurological studies; development of spatially-oriented databases for digital brain images; nuclear magnetic resonance evaluation of stroke; physiologic imaging of human brain tumors.

Selected Publications:

Murray AM1,2, Hsu FC3, Williamson JD4, Bryan RN5, Gerstein HC6,7, Sullivan MD8, Miller ME3, Leng I3, Lovato LL3, Launer LJ9; Action to Control Cardiovascular Risk in Diabetes Follow-On Memory in Diabetes (ACCORDION MIND) Investigators.: ACCORDION MIND: results of the observational extension of the ACCORD MIND randomised trial Diabetolgia 2017 Jan;60(1):69-80. Epub 2016 Oct 20. 1 (69-80): 69-80,2017.

R. Nick Bryan, MD, PhD R. Nick Bryan, MD, PhD R. Nick Bryan, MD, PhD R. Nick Bryan, MD, PhD R. Nick Bryan, MD, PhD R. Nick Bryan, MD, PhD: Science to Practice: Can Focused Ultrasound Disruption of the Blood-Brain Barrier Improve Malignant Brain Tumor Treatment Outcomes?,” Radiology : 2016.

Freedman BI1, Gadegbeku CA2, Bryan RN3, Palmer ND4, Hicks PJ5, Ma L6, Rocco MV6, Smith SC5, Xu J5, Whitlow CT7, Wagner BC7, Langefeld CD8, Hawfield AT6, Bates JT9, Lerner AJ10, Raj DS11, Sadaghiani MS3, Toto RD12, Wright JT Jr13, Bowden DW4, Williamson JD14, Sink KM14, Maldjian JA15, Pajewski NM8, Divers J8; African American–Diabetes Heart Study MIND (AA-DHS MIND) and Systolic Blood Pressure Intervention Trial (SPRINT) Research Groups.: APOL1 renal-risk variants associate with reduced cerebral white matter lesion volume and increased gray matter volume. Kidney Int 90 (2): 440-9,2016.

Dolui S, Wang Z, Wang DJ, Mattay R, Finkel M, Elliott M, Desiderio L, Inglis B, Mueller B, Stafford RB, Launer LJ, Jacobs DR Jr, Bryan RN, Detre JA.: Comparison of Noninvasive MRI Measurements of Cerebral Blood Flow in a large Multisite Cohort, has been reviewed by two external referees. Journal of Cerebral Blood Flow & Metabolism 36 (7): 1244-56,2016.

Barzilay JI1, Morgan TM2, Murray AM3, Bryan RN4, Williamson JD5, Schnall A6, Launer LJ7: Brain MRI Volume Findings in Diabetic Adults With Albuminuria: The ACCORD-MIND Study J Gerontol A Biol Sci Med Sci. 71 (6): 803-10,2016.

Mohammad Salehi Sadaghiani, MD, MPH; Meng-Kang Hsieh, MS; Ilya Nasrallah, MD, PhD; Ragini Verma; PhD; Drew Parker, Sc.B; Guray Erus, PhD, Mohan Suyash; MD, Emmanuel Botzolakis, MD, PhD; R. Nick Bryan, MD, PhD: Brain white matter lesions; new insights in our understanding of leukoaraiosis ASNR 54th Annual Meeting : 2016.

I Nasrallah, M Hsieh, H Battapady, G Erus, L Launer, C Davatzikos, R Bryan: White matter lesion penumbra shows abnormalities on structural and functional MRI in CARDIA study ASNR 54th Annual Meeting : 2016.

A Al Yassin, M Salehi Sadaghiani, S Mohan, E Botzolakis, R Bryan, I Nasrallah: It's about time: A Time-Activity Study in Neuroradiology ASNR 54th Annual Meeting and Symposium : 2016.

Espeland MA1, Erickson K2, Neiberg RH3, Jakicic JM4, Wadden TA5, Wing RR6, Desiderio L5, Erus G5, Hsieh MK5, Davatzikos C5, Maschak-Carey BJ5, Laurienti PJ7, Demos-McDermott K6, Bryan RN5; Action for Health in Diabetes Brain Magnetic Resonance Imaging (Look AHEAD Brain) Ancillary Study: Brain and White Matter Hyperintensity Volumes After Ten Years of Random Assignment to Lifestyle Intervention Diabetes Care 39 (5): 764-71,2016.

Botzolakis E., Nasrallah, I., Kundel, H., Herskovits, E., Bryan, R., Mohan, S.: Validation of an Expert-based Bayesian Network for Discriminating Disease Affecting the Basal Ganglia and Thalamus ASNR 54th Annual Meeting : 2016.

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Academic Contact Info

Department of Radiology
Perelman School of Medicine
3700 Hamilton Walk, Richards Building 7th Floor

Philadelphia, PA 19146
Phone: (215) 746-4062
Patient appointments: 800-789-PENN (7366)

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