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Philippe O. Szapary, MD, FACP

Philippe O. Szapary, MD, FACP Provider Not Employed by Penn Medicine

Adjunct Associate Professor of Medicine

Languages spoken:

  • French
  • Spanish

Dr. Szapary is a private practice physician who is not employed by Penn Medicine.

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About Dr. Philippe O. Szapary

Recognized by Best Doctors in America 2005-2006, 2007-2008, 2009-2010

Clinical Specialties


  • Cardiology

Programs & Centers:

  • Preventive Cardiovascular Program

Board Certification:

  • Internal Medicine, 1997

Clinical Expertise:

  • Cardiac Risk Reduction
  • Cardiology Risk Intervention
  • Cholesterol and Lipid Disorders
  • High Cholesterol (Hypercholesterolemia)
  • Hyperlipidemia (Hyperlipoproteinemia)
  • Hypertension
  • Lipid Disorders
  • Preventive Heart Care

Description of Clinical Expertise

I continue to work in the Cardiovascular Prevention Clinic in the Perleman Center 2 half days per month seing patients for complicated dyslipidemias, hypertension, obesity, diabetes and CV risk stratification.

Since 2012, I have also started seing patients with psoriasis and psoriatic arthritis for CV risk evaluation and treatment. This came out of my research interest in these diseases and my collaboration with Dr. Nehal Mehta (cardiology) and Joel gelfand (Dermatology).

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Chicago School of Medicine
Residency: UCSF Medical Center and Hospital


American College of Cardiology, National American College of Physicians, National American Federation of Medical Researchers, National American Heart Association, National American Society of Nutritional Sciences, National None, International None, Local Society of General Internal Medicine, National

Hospital Affiliation

Dr. Szapary is a private practice physician who is not employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

My expertise is in the clinical development of novel pharmaceutical compounds both large and small molecules.

Since leaving the full-time faculty at the University of Pennsylvania in 2005, I have worked in Cardiovascular early stage drug development (Phase 0-2)and immunology late stage development (Phase 2b-3). From 2005-2007, I worked at Wyeth Research focused on nuclear hormone receptor targets (PPAR, FXR, LXR) in dyslipidemia and diabetes.

From 2007 onward, I have worked on the clinical development of novel monoclonal antibodies targeting IL-12 and/or IL-23 in immune mediated diseases. This work led to the global approval of ustekinumab (Stelara) in 65+ countries for moderate to severe psoriasis. Currently I am focused on developing ustekinumab in psoriatic arthrtitis as well as overseeing a a Phase 3 program in Crohn's Disease and a proof of concept study in Rheumatoid Arthritis. This body of work led to Stelara being awarded the 2012 International Prix Galien Award for Best Product.

Selected Publications:

Bloedon L and Szapary P: Flaxseed: A functional food for cardiovascular risk reduction Nutr Rev 62 : 18-27,2004.

Foster G, Wyatt HR, Hill JO, McGuckin G, Brill C, Mohammed SB, Szapary PO, Rader DJ, Edman JS, Klein SK: A multi-center, randomized, controlled clinical trial of the Atkin's diet NEJM 348 : 2082-2090,2003.

Szapary P, Wolfe ME, Bloedon L, Cucchiara A, DerMarderosian A, Cirigliano M, Rader DJ: Guggulipid for the treatment of hypercholesterolemia: A randomized, controlled trial JAMA 290 : 765-772,2003.

Szapary P, Wolfe ME, Cucciara A, Reilly MP, Rader DJ: Metabolic effects of Guggulipid: Results from a randomized controlled factor FACT 8 : 542,2003.

Szapary P: Complementary and alternative medicine therapies in the management of lipid disorders: A review of current evidence Textbook of Complementary and Alternative Medicine : 245-257,2003.

Guerra C and Szapary P: The definition of myocardial infarction [Letter to the Editor] Arch Int Med 163 : 245,2003.

Basch E, Ulbricht C, Kuo G, Szapary P, Smith M: Therapeutic applications of Fenugreek Alternative Medicine Review 8 : 20-27,2003.

Szapary P: Can a perioperative nutritional drink help patients before heart bypass surgery Focus on Alternative and Complementary Therapies (FACT) 8 : 35-36,2003.

Szapary P and DerMarderosian A: Herbal medicine and drug-herb interactions case Medical Nutrition and Disease 3rd edition : 90-95,2003.

Basch E, Ulbricht C, Harrison M, Sollars D, Smith M, Dennehy C, Szapary P: Alfalfa (Medicago sativa L): A clinical decision support tool J Herbal Pharmacother 3 : 69-90,2003.

Academic Contact Info

Welsh & McKean Roads
3rd floor
Mailstop: 32-3-3

Spring House, PA 19477
Phone: (215) 793-7612
Fax: (610) 651-7271
Patient appointments: 800-789-7366 (PENN)

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