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Patricia A. Takach, MD, FAAAAI

Patricia A. Takach, MD, FAAAAI Physician

Co-Director of Allergy and Immunology Clinical Programs Course Director, Elective in Allergy and Immunology Interim Chief, Section of Allergy and Immunology Associate Professor of Clinical Medicine

Dr. Takach is employed by Penn Medicine.

About Dr. Patricia A. Takach

Recognized by America's Top Docs, 2015 - 2018

Recognized by Best Doctors in America 2017, 2018

Recognized in Philadelphia magazine's annual Top Docs issues, 2016 - 2019

Epic Governance Committee Member, Hospital of the University of Pennsylvania

Health Care Hero, University of Pennsylvania Health System, 2014, 2015

The Burton Zweiman Teaching Award, Depart of Medicine, Perelman School of Medicine ath the University of Pennsylvania, 2013

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Allergy and Immunology

Programs & Centers:

Board Certification:

  • Allergy and Immunology, 2005

Clinical Expertise:

  • Agammaglobulinemia 
  • Allergen Immunotherapy
  • Allergic Aspergillosis
  • Allergic Asthma
  • Allergic Disorders
  • Allergic Esophagitis
  • Allergic Gastroenteritis
  • Allergic Rhinitis
  • Allergic Rhinitis to Pollen
  • Allergic Rhinosinusitis
  • Allergic Wheezing
  • Allergies
  • Allergy Shots
  • Allergy Testing
  • Allergy to Eggs
  • Allergy to Mold
  • Allergy to Peanuts
  • Allergy to Seafood
  • Anaphylaxis
  • Anesthetic Agent Testing
  • Angioedema
  • Antibody Deficiency
  • Aspirin Desensitization
  • Asthma
  • Bee Sting Allergy
  • Chronic Cough
  • Chronic Sinus Infection
  • Common Variable Immune Deficiency
  • Complement Deficiency 
  • Counseling Regarding Allergic Disorders
  • Drug Allergy
  • Environmental Allergy
  • Feno Test
  • Food Allergy
  • Food Allergy Testing
  • Food Challenge Testing
  • Frequent Infections
  • Fungal Skin Testing
  • Gluten Allergy
  • Hereditary Angioedema
  • High Eosinophil Count
  • Hives (Urticaria)
  • Humoral Immune Defect
  • Hyper IgE Syndrome 
  • Hyper IgM Syndrome 
  • Hypogammaglobulinemia
  • IgG Subclass Deficiency 
  • Immune Dysregulation
  • Immunoglobulin Replacement Therapy
  • Immunologic Deficiency Disorders
  • Immunotherapy
  • Insect Sting Allergy
  • Job Syndrome
  • Latex Allergy
  • Mast Cell Activation Syndrome
  • Milk Allergy
  • Nonallergic Rhinitis
  • Penicillin Allergy
  • Penicillin Challenge
  • Persistent Asthma
  • Post-Nasal Drip
  • Prick Skin Test
  • Primary Humoral Immunodeficiencies
  • Primary Immunodeficiency
  • Pulmonary Function Tests
  • Recurrent Abscesses
  • Recurrent Infections
  • Scratch Test
  • Seasonal Allergies
  • Selective IgA Deficiency
  • Severe Asthma
  • Severe Combined Immunodeficiency
  • Sinonasal Mucocele
  • Skin Test
  • Soy Allergy
  • Specific Antibody Deficiency
  • Sublingual Immunotherapy
  • Tree Nut Allergies
  • Vasomotor Rhinitis
  • Venom Allergies
  • Wheat Allergy
  • Wheezing
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Boston University School of Medicine
Residency: University Hospitals of Cleveland
Residency: Hahnemann University Hospital
Fellowship: SUNY at Stony Brook Medical Center


American Academy of Allergy, Asthma and Immunology, National American Academy of Allergy, Asthma and Immunology, National American Academy of Allergy, Asthma and Immunology, National American Academy of Allergy, Asthma and Immunology, National Clinical Immunology Society, International Pennsylvania Medical Society, Local

Hospital Affiliation

Dr. Takach is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Selected Publications:

Le Coz C, Bengsch B, Khanna C, Trofa M, Ohtani T, Nolan BE, Henrickson SE, Lambert MP, Kim TO, Despotovic JM, Feldman S, Fadugba OO, Takach P, Ruffner M, Jyonouchi S, Heimall J, Sullivan KE, Wherry EJ, Romberg N.: Common variable immunodeficiency-associated endotoxemia promotes early commitment to the T follicular lineage. Journal of Allergy and Clinical Immunology : 2019.

Romberg N, Le Coz C, Glauzy S, Schickel JN, Trofa M, Nolan BE, Paessler M, LuQing Xu M, Lambert M, Lakhani SA, Khokha MK, Jyonouchi S, Heimall J, Takach P, Maglione PJ, Catanzaro J, Hsu FI, Sullivan KE, Cunningham-Rundles C, Meffre E.: Patients with common variable immunodeficiency with autoimmune cytopenias exhibit hyperplastic yet inefficient germinal center responses. Journal of Allergy and Clinical Immunology 143 (1): 258-265,2019.

Kathleen Y. Wang, Huang KH, Takach P, Fadugba O, Apter A, Kelsen J, Jyonouchi S, Sullivan K, MD, PhD, FAAAAI: An Adult with Enteritis and Hypogammaglobulinemia Found to Have Heterozygous STXBP2 Mutation Journal of Allergy and Clinical Immunology : 2017.

Ganetsky A1, Takach PA2, Lynch DM3, Krause TM4, Teh JS2, Stadtmauer EA5, Castells M3, Weiss BM5.: Melphalan desensitization following immediate hypersensitivity in a patient undergoing conditioning for autologous hematopoietic cell transplantation. J Allergy Clin Immunol Pract. 2016 May-Jun;4(3):555-6. 4 (3): 555-556,2016.

Monica Bhagat, MD, Joshua A. Steinberg, MD, Frank Silvestry, MD, Lea Surrey, MD, Andrea J. Apter, MD MA MSc FAAAAI, Patricia A. Takach, MD FAAAAI, Benjamin P. Soule, MD: Suspected Non-Infectious Prosthetic Valve Inflammatory Dehiscence In X-Linked Chronic Granulomatous Disease Journal of Allergy and Clinical Immunology : 2014 .

Patricia Takach: Allergies to Antibiotics, in The Intensive Care Unit Manual, 2nd Edition. Book : 316-323,2014.

Agi CU, Gober MD, Ferenczi K, Takach P, Eagle RC, Rosenbach M.: "A case of adult onset asthma with periocular xanthogranulomas." Archives of Dermatology 147 (10): 1230-1231,2011.

Zemble RM, Takach PA, Levinson AI.: "The Relationship between hypogammaglobulinemia, monoclonal gammopathy of undetermined significance and humoral Immunodeficiency: a case series." Journal of Clinical Immunology : 2011.

Marks K, Takach P.: "Mycoplasma hominis septic arthritis in an adult with X-linked agammaglobulinemia." Annals of Allergy, Asthma and Immunology : A101,2010.

Apter AJ, Wan F, Chittams J, Adelsberg B, Andrew S, Blaiss M, Columbo M, Davidson A, Detjen P, DeCotiis B, Dvorin D, Ford L, Gawchik S, Gillman S, Grijnsztein M, Gross GN, Hoffman M, Lanz M, Stillerman A, Takach P, Rebbeck T.: "Risk Factors for Adults with a History of Penicillin Allergy." Journal of Allergy and Clinical Immunology 119 (1): S269,2007.

Academic Contact Info

Section of Allergy and Immunology
Division of Pulmonary, Allergy and Critical Care
Perelman School of Medicine at the University of Pennsylvania
3737 Market Street, 3rd Floor

Philadelphia, PA 19104
Phone: (215) 662-2775
Patient appointments: 800-789-7366 (PENN)

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