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Pasquale Santangeli, MD, PhD

Pasquale Santangeli, MD, PhD Physician

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Santangeli is employed by Penn Medicine.

In New Jersey, providers are affiliated with Penn Medicine through Clinical Health Care Associates of New Jersey.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Cardiology

Programs & Centers:

Board Certification:

  • Cardiology

Clinical Expertise:

  • Ablation of Idiopathic Ventricular Tachycardia
  • Ablation of Ischemic Ventricular Tachycardia
  • Atrial Fibrillation (Afib)
  • Atrial Fibrillation Treatment
  • Biventricular Device Implantation
  • Biventricular Device Optimization
  • Bradycardia
  • Cardiac Catheter Ablation
  • Complex Arrhythmia
  • Electrocardiogram (EKG or ECG)
  • Electrocardiography (ECG or EKG)
  • Electrophysiology (EP) Testing
  • Epicardial Ablation
  • Heart Palpitations
  • Heart Rhythms - Slow/Fast
  • Implantable Cardioverter Defibrillator
  • Intracardiac Echocardiography (ICE)
  • Intracardiac Ultrasound
  • Pulmonary Vein Antrum Isolation (PVAI)
  • Radiofrequency Ablation (RFA)
  • Supraventricular Tachycardia (SVT)
  • Syncope (Fainting)
  • Tachycardia
  • Ventricular Tachycardia
  • Ventricular Tachycardia Ablation
  • Wolff-Parkinson-White Syndrome

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Amerihealth
  • NJ Medicaid
  • NJ Medicare
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Rome
Fellowship: Catholic University of the Sacred Heart
Fellowship: Stanford University Medical Center


Heart Rhythm Society, National

Hospital Affiliation

Dr. Santangeli is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Selected Publications:

Liang Jackson J, Santangeli Pasquale: Finding the needle in the haystack: Role of high resolution mapping to identify pulmonary vein conduction gaps. International journal of cardiology 272 : 211-212,2018.

Briceño David F, Markman Timothy M, Lupercio Florentino, Romero Jorge, Liang Jackson J, Villablanca Pedro A, Birati Edo Y, Garcia Fermin C, Di Biase Luigi, Natale Andrea, Marchlinski Francis E, Santangeli Pasquale: Catheter ablation versus conventional treatment of atrial fibrillation in patients with heart failure with reduced ejection fraction: a systematic review and meta-analysis of randomized controlled trials. Journal of Interventional Cardiac Electrophysiology 53 (1): 19–29,2018.

Muser Daniele, Santangeli Pasquale, Selvanayagam Joseph B, Nucifora Gaetano: Role of Cardiac Magnetic Resonance Imaging in Patients with Idiopathic Ventricular Arrhythmias. Current cardiology reviews : 2018.

Santangeli Pasquale, Lin David: Reaching for the summit: The dark side of ablating ventricular arrhythmias from within the coronary venous system. Pacing and clinical electrophysiology: PACE 41 (9): 1069-1070,2018.

Shirai Yasuhiro, Liang Jackson J, Garcia Fermin C, Supple Gregory E, Callans David J, Zado Erica S, Marchlinski Francis E, Santangeli Pasquale: QRS morphology shift following catheter ablation of idiopathic outflow tract ventricular arrhythmias: Prevalence, mapping features, and ablation outcomes. Journal of cardiovascular electrophysiology : 1-8,2018.

Hayashi Tatsuya, Liang Jackson J, Muser Daniele, Shirai Yasuhiro, Enriquez Andres, Garcia Fermin C, Supple Gregory E, Schaller Robert D, Frankel David S, Lin David, Nazarian Saman, Zado Erica S, Arkles Jeffrey S, Dixit Sanjay, Callans David J, Marchlinski Francis E, Santangeli Pasquale: Epicardial ventricular tachycardia in ischemic cardiomyopathy: Prevalence, electrophysiological characteristics, and long-term ablation outcomes. Journal of cardiovascular electrophysiology : 1-10,2018.

Liang Jackson J, D'Souza Benjamin A, Betensky Brian P, Zado Erica S, Desjardins Benoit, Santangeli Pasquale, Chik William W, Frankel David S, Callans David J, Supple Gregory E, Hutchinson Mathew D, Dixit Sanjay, Schaller Robert D, Garcia Fermin C, Lin David, Riley Michael P, Marchlinski Francis E: Importance of the Interventricular Septum as Part of the Ventricular Tachycardia Substrate in Nonischemic Cardiomyopathy. JACC Clinical electrophysiology 4 (9): 1155-1162,2018.

Romero Jorge, Santangeli Pasquale, Pathak Rajeev K, Grushko Michael, Briceno David, Cerrud-Rodriguez Roberto, Quispe Renato, Grupposo Vito, Di Biase Luigi: Bundle branch reentrant ventricular tachycardia: review and case presentation. Journal of interventional cardiac electrophysiology: an international journal of arrhythmias and pacing 52 (3): 385-393,2018.

Gordon Jeffrey P, Liang Jackson J, Pathak Rajeev K, Zado Erica S, Garcia Fermin C, Hutchinson Mathew D, Santangeli Pasquale, Schaller Robert D, Frankel David S, Marchlinski Francis E, Supple Gregory E: Percutaneous cryoablation for papillary muscle ventricular arrhythmias after failed radiofrequency catheter ablation. Journal of cardiovascular electrophysiology : 2018.

Liang Jackson J, Mohanty Sanghamitra, Fahed Joe, Muser Daniele, Briceno David F, Burkhardt J David, Arkles Jeffrey S, Supple Gregory E, Frankel David S, Nazarian Saman, Garcia Fermin C, Callans David J, Dixit Sanjay, Di Biase Luigi, Natale Andrea, Marchlinski Francis E, Santangeli Pasquale: Bailout Atrial Balloon Septoplasty to Overcome Challenging Left Atrial Transseptal Access for Catheter Ablation of Atrial Fibrillation. JACC. Clinical electrophysiology 4 (8): 1011-1019,2018.

Academic Contact Info

Hospital of the University of Pennsylvania
Clinical Cardiac Electrophysiology
9 Founders Building
3400 Spruce Street

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)