Michael R. Costello, MD

Hematology, Medical Oncology

5.0 with 478 ratings

Sees patients age 18 and up

Michael R. Costello, MD

Hematology, Medical Oncology

5.0 with 478 ratings

Sees patients age 18 and up

Medical Director. The Abramson Cancer Center at Chester County Hospital
Dr. Costello is a Penn Medicine physician.

Call 800-789-7366 Request Appointment

Meet Dr. Costello

Recognized by Main Line Today's Top Doctor's 2016 issue

Recognized in Philadelphia magazine's annual Top Docs issues for 2020 and 2021

Clinical expertise includes: Cancer Immunotherapy and Spinal Tumor.

All Cancer Types

Acute Lymphocytic Leukemia (ALL)
Acute Myeloid Leukemia (AML)
Acute Promyelocytic Leukemia
Adenocarcinoma of the Head and Neck
Adjuvant Chemotherapy
Adrenal Cancer (Adrenocortical Carcinoma)
Adult T-Cell Leukemia
Adult T-Cell Lymphoma
AIDS Related Malignancies
All Cancer Types
Amyloidosis
Anal Cancer
Anaplastic Large Cell Lymphoma
Anaplastic Thyroid Cancer
Anemia
Anemia and Bone Marrow Disorders
Anemia of Chronic Disease
Anemia of Pregnancy
Anticoagulation
Antiphospholipid Syndrome
Antithrombin Deficiency
Aplastic Anemia
Autoimmune Hemolytic Anemia
B12 Deficiency Anemia
Bile Duct Cancer (Cholangiocarcinoma)
Bladder Cancer
Bleeding Disorder
Blood Cancer
Blood Clot (Thrombus)
Blood Clotting Disorders (Blood Coagulation)
Blood Disorders
Blood Platelet Disorders
Bone Marrow Biopsy
Bone Marrow Failure Syndromes
Bone Sarcoma
Bone Tumors
Brain Tumor
Breast Cancer
Breast Cancer Immunotherapy
Burkitt Lymphoma
Cancer During Pregnancy
Cancer Immunotherapy
Cancer Pain
Cancer Survivor
Carcinoid Tumors
Carcinoma In Situ of Breast
Carcinoma of Unknown Primary
Castleman Disease
Catastrophic Antiphospholipid Syndrome
Cervical Cancer
Chemotherapy for Cancer
Chronic Lymphocytic Leukemia (CLL)
Chronic Myeloid Leukemia (CML)
Chronic Myelomonocytic Leukemia (CMML)
Clinical Trials
Coagulation Disorders
Cold Agglutinin Disease
Colon Cancer
Colon Tumor
Cooley's Anemia
Cryoglobulinemia
Cutaneous Lymphoma
Deep Thrombophlebitis
Deep Vein Thrombosis
Diamond Blackfan Anemia
Ductal Carcinoma in Situ (DCIS)
Dyskeratosis Congenita
Endocrine Complications of Cancer Therapy
Endometrial Cancer
Eosinophilic Granuloma
Erdheim-Chester Disease
Esophageal Cancer
Essential Thrombocytosis
Ewings Sarcoma
Factor Eight Disorder
Factor Nine Deficiency
Factor V Leiden
Fallopian Tube Cancer
Familial Aplastic Anemia
Fanconi Anemia
Folic Acid Deficiency
Follicular Thyroid Cancer
Gallbladder Cancer
Gastrointestinal Cancer (GI Cancer)
Gastrointestinal Stromal Tumors (GIST)
Gestational Trophoblastic Disease
Giant Cell Tumor of the Bone
Glioblastoma
Glioma
Glucose-6-Phosphate Dehydrogenase Deficiency
Graft Versus Host Disease
Hairy Cell Leukemia
Hand-Foot Syndrome
HELLP Syndrome
Hematologic Malignancies
Hemochromatosis
Hemoglobinopathies
Hemolytic Anemia
Hemolytic Uremic Syndrome
Hemophilia
Heparin-Induced Thrombocytopenia
Hereditary Cancer Risk
Hereditary Spherocytosis
Histiocytosis
Hodgkin Lymphoma
Hypercoagulable State
Hypogammaglobulinemia
Idiopathic Thrombocytopenic Purpura
Inflammatory Breast Cancer (IBC)
Intraocular Lymphoma
Iron Deficiency Anemia
Iron Metabolism Disorders
Kaposi Sarcoma
Kidney Cancer
Large Granular Lymphocytic Leukemia
Laryngeal Cancer
Leiomyosarcoma
Leukemia
Leukocytosis
Leukopenia
Light Chain Disorders
Liver Cancer
Lobular Carcinoma in Situ (LCIS)
Low Platelet Count (Thrombocytopenia)
Lung Cancer
Lupus Anticoagulant
Lymphoma
Lymphopenia
Male Breast Cancer
Marginal Zone Lymphoma
Maternal Anticoagulation
Maternal Hematologic Disorders
Maternal Thrombophilia
Mediastinal Lymphoma
Medullary Cancer of Thyroid
Melanoma
Merkel Cell Carcinoma
Mesothelioma
Monoclonal Gammopathy of Undetermined Significance (MGUS)
Mouth Cancer (Oral Cancer)
Mucosa-Associated Lymphoid Tissue Lymphoma
Mucosal Melanoma
Multiple Myeloma
Myelodysplastic Syndromes (MDS)
Myeloproliferative Neoplasms (MPNs)
Neoadjuvant Chemotherapy
Neuroendocrine Tumor
Neutropenia
Non-Hodgkin Lymphoma
Non-Small Cell Lung Cancer
Oropharyngeal Cancer
Osteosarcoma
Ovarian Cancer
Pancreatic Cancer
Pancytopenia
Papillary Thyroid Cancer
Paroxysmal Nocturnal Hemoglobinuria
Partial Thromboplastin Time Blood Test
Penile Cancer
Peripheral T-Cell Lymphoma
Pernicious Anemia
Petechiae
Pituitary Cancer
Plasma Cell Dyscrasia
POEMS Syndrome
Polycythemia
Porphyria
Post Thrombotic Syndrome
Primary CNS Lymphoma
Primary Myelofibrosis
Primary Systemic Amyloidosis
Prolymphocytic Leukemia
Prostate Cancer
Protein C Deficiency
Protein S Deficiency
Prothrombin Gene Mutation
Pure Red Cell Aplasia
Purpura
Rectal Cancer
Recurrent Thrombosis
Red Blood Cell Disorders
Refractory Anemia With Excess Blasts
Rhabdomyosarcoma
Sarcoma
Secondary Polycythemia
Sezary Syndrome
Sickle Cell Disease
Sinus Cancer
Skin Cancer
Small Cell Lung Cancer
Spinal Tumor
Splenic Sequestration
Splenomegaly
Squamous Cell Carcinoma of the Head and Neck
Stomach Cancer (Gastric Cancer)
Sweat Gland Carcinoma
Targeted Therapy
Testicular Cancer
Thalassemia
Thoracic Cancer
Throat Cancer
Thrombocytosis
Thrombophilia
Thrombotic Disorders
Thrombotic Thrombocytopenic Purpura
Thyroid Cancer
Transformed Lymphoma
Transitional Cell Carcinoma
Ureteral Cancer
Urethral Cancer
Uterine Cancer
Vaginal Cancer
Vaginal Melanoma
Venous-Occlusive Crisis
Von Willebrand Disease
Vulvar Cancer
Waldenstrom Macroglobulinemia (WM)
White Blood Cell Disorders

Show All Expertise

Programs and Centers

Penn Medicine's programs and centers combine doctors from many disciplines to coordinate care from start to finish. Dr. Costello is part of these programs:

Abramson Cancer Center
Penn Classical (Non-Malignant) Hematology Program

Board Certification

Medical Oncology, 2011

Education and Training

Medical School: Penn State Milton S. Hershey Medical Center
Residency: Temple University Hospital
Fellowship: Temple University Hospital

Primary Location

Penn Hematology/Oncology Exton

720 West Lincoln Highway
The Commons at Oaklands
Exton, PA 19341

Map Call 800-789-7366

View details

Abramson Cancer Center Chester County Hospital

Suite 101
440 East Marshall Street
West Chester, PA 19380

Map Call 800-789-7366

View details

Penn Medicine Hospital Privileges

Chester County Hospital: Has privileges to treat patients in the hospital.
Penn Presbyterian Medical Center: On the medical staff, but does not have privileges to treat patients in the hospital.

Overall Ratings

out of 5 ; Ratings;

The Patient Satisfaction Rating is an average of all responses to the care provider related question shown above from our internal platform, PMX Feedback. Responses are measured on a scale of 1 to 5 with 5 being the best score. Scores reflect either the most recent 12 months of surveys or the most recent 30 surveys overall. Data is updated monthly and comments remain on the profile for 12 months.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Patients that are treated in outpatient or hospital environments may receive different surveys.

Please contact the practice and/or the member services department of your insurance company for specific details before receiving services. Providers may participate in some, but not all, products offered by a health plan; providers may also accept plans at some practice locations but not others.

Aetna US Healthcare
Amerihealth Caritas
Amerihealth Caritas Medicare
Centivo Health Plan
Cigna
Cigna HealthSpring
Clover Health Plan
Devon Health Services (Americare)
Gateway Health Plan
Geisinger Health Plan
Geisinger Medicaid
Global Medical Management
HealthAmerica / HealthAssurance, a Coventry Plan
HealthPartners
HealthPartners Medicare
HealthSmart
Highmark Blue Shield
Homestead Smart Health Plans/Claim Watcher
Humana / Choicecare

Humana / Medicare
Imagine Health 360
Independence Blue Cross (Keystone East)
Keystone First
Keystone First Medicare
Multiplan
NJ Qualcare
Oscar Health Plan of PA
Oxford Health Plan
PA Health and Wellness (Centene) Medicare
PA Medicaid
PA Medicare
Provider Partners Health Plan
Rail Road Medicare / Palmetto GBA
Tricare
United Healthcare
UnitedHealthcare Community Plan
US Family Health Plan
Veterans Choice Program

Selected Publications

Cosstello MR, Meropol NJ, Denlinger CS, Engstrom PF, Wright JJ, Li T, McLaughlin S, Beard M, Cimildoro R, Cohen SJ.: A phase II trial of the proteasome inhibitor bortezomib in patients with recurrent or metastatic adenocarcinoma of the bile duct or gallbladder (NCI #6135). Journal of Clinical Oncology, 2009 ASCO Annual Meeting Proceedings (Post Meeting Edition). 27 (155): e15605,2009.

Michael Costello: Current Recommendations for Screening for Cervical Cancer Temple University Hospital Morning Conference Series : 2006.

Michael Costello: Treatment of Thromboembolic Disease in Oncological Patients Temple University Hospital Morning Conference Series : 2005.

Michael Costello: Methicillin Resistant Staph Aureus Infection in a 26 year old patient Temple University Hospital Morning Conference Series : 2005.

Academic Contact Information

Penn Hematology/Oncology
Suite 201
440 East Marshall Street
West Chester , PA 19380
Phone: 610-738-2500
Patient appointments: 800-789-7366