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Maurizio Tomaiuolo, PhD Researcher

Research Assistant Professor of Medicine

Dr. Tomaiuolo is employed by Penn Medicine.

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Clinical Specialties

Programs & Centers:


American Heart Association, National International Society of Thrombosis and Hemostasis, International North American Society on Thrombosis and Hemostasis, National

Hospital Affiliation

Dr. Tomaiuolo is employed by Penn Medicine.


Description of Research Expertise:

Mathematical modeling

Selected Publications:

Gao, Z.; Xia, H., Zauberman, J.; Tomaiuolo, M.; Ping, J.; Zhang, Q.; Ducos, P.; Ye, H.; Wang, S.; Yang, X.; Lubna, F.; Luo, Z.; Ren, L.; Johnson, A.T.C.: Detection of Sub-fM DNA with Target Recycling and Self-Assembly Amplification on Graphene Field Effect Biosensors Nano Letters 18 (6): 3509-3515,2018.

I. Poventud-Fuentes, B.J. Samelson-Jones, A. Cuker, S.L. Diamond, L.F. Brass, M. Tomaiuolo: Development of a microfluidic platform to assess thrombin generation in FVIII deficient whole blood under flow conditions Poster at GRC hemostasis, Waterville Valley, NH : 2018.

M. Tomaiuolo, L.F. Brass: Joining forces to understand hemostasis and thrombosis: A call to communicate: Comment on “Modeling thrombosis in silico: Frontiers, challenges, unresolved problems and milestones” Physics of Life Reviews : 2018.

M. Tomaiuolo, C.N. Matzko, I. Poventud-Fuentes, J. Weisel, L.F. Brass, T.J. Stalker: Context matters: Influence of the physical environment on the spatial distribution of platelet activation and thrombin activity during hemostasis in vivo. Poster at GRC hemostasis, Waterville Valley, NH : 2018.

T.J. Stalker, L. Nettey, C. Matzko, I. Poventud-Fuentes, T.T. Marar, T. Sinno, L.F. Brass, M. Tomaiuolo.: Examining the relative roles of biophysical and biochemical mechanisms of thrombin inhibition during hemostasis. Poster at GRC hemostasis, Waterville Valley, NH : 2018.

S.M. Mirramezani, B.A. Herbig, T.J. Stalker, L. Nettey, M. Cooper, J.W. Weisel, S.L. Diamond, T. Sinno, S.C. Shadden, L.F. Brass, M. Tomaiuolo: Convection denied: platelet packing density is an independent regulator of the hemostatic response to injury. Journal of Thrombosis and Hemostasis 16 (5): 973-983,2018.

M. Tomaiuolo, L.F. Brass, T.J. Stalker.: Regulation pf platelet activation and coagulation and its role in vascular injury and arterial thrombosis. Interventional Cardiology Clinics 6 (1): 1-12,2017.

L.F. Brass, P. Ma, M. Tomaiuolo, S.L. Diamond, T.J. Stalker: A systems approach to the platelet signaling network and the hemostatic response to injury Platelets in Thrombotic and Non-Thrombotic Disorders : 2017.

C. Matzko, M. Tomaiuolo, I. Poventud-Fuentes, L. Nettey, J. Weisel, L. Brass, T. Stalker: Analysis of Venous and Arterial Hemostatic Plugs Reveals Strikingly Similar Composition and a Gradient of Platelet Activation Poster at ISTH 2017, Berlin, Germany : 2017.

Tomaiuolo M, Kottke M, Matheny RW, Reifman J, Mitrophanov AY.: Computational identification and analysis of signaling subnetworks with distinct functional roles in the regulation of TNF production. Mol Biosyst. 12 (3): 826-38,2016 .

Academic Contact Info

421 Curie Blvd
821 BRB II

Philadelphia , PA 19104
Phone: (215) 573-3541