Find a Doctor or Practice Location

You can also search for providers and practices at Penn Medicine Lancaster General Health or Princeton Health.

I am searching for a
Reset Form
Lili Wang, PhD

Lili Wang, PhD Researcher

Research Associate Professor of Medicine

Dr. Wang is employed by Penn Medicine.

No Patient Satisfaction Reviews
Why not?

There is no publicly available rating for this medical professional for one of the following reasons:

  1. He or she is not employed by Penn Medicine.
  2. He or she does not see patients in a medical practice setting.
  3. He or she sees patients but has not yet received the minimum 30 patient satisfaction reviews in the past 12 months, ensuring that the rating is statistically reliable and a true reflection of patient satisfaction.

Clinical Specialties


  • Medical Genetics

Programs & Centers:


American Society of Gene and Cell Therapy, National

Hospital Affiliation

Dr. Wang is employed by Penn Medicine.


Description of Research Expertise:

Viral vectors, gene therapy, immune response, metabolic diseases and animal models

Selected Publications:

Yang Y*, Wang L*, Bell P, McMenamin D, He Z, White J, Yu H, Xu C, Morizono H, Musunuru K, Batshaw ML, Wilson JM.: A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice Nature Biotechnology 34 (3): 334-338,2016.

Wang L, Bell P, Somanathan S, Wang Q, He Z, Yu H, McMenamin D, Goode T, Calcedo R, Wilson JM.: Comparative Study of Liver Gene Transfer With AAV Vectors Based on Natural and Engineered AAV Capsids Molecular Therapy 23 (12): 1877-1887,2015.

Bissig-Choisat B*, Wang L*, Legras X, Saha PK, Chen L, Bell P, Pankowicz FP, Hill MC, Barzi M, Leyton CK, Leung HC, Kruse RL, Himes RW, Goss JA, Wilson JM, Chan L, Lagor WR, Bissig KD.: Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model Nature Communications 6 (7339): 2015.

Mays LE, Wang L, Lin J, Bell P, Crawford A, Wherry EJ, Wilson JM.: AAV8 induces tolerance in murine muscle as a result of poor APC transduction, T cell exhaustion and minimal MHCI upregulation on target cells. Molecular Therapy 22 (1): 28-41,2014.

Wang L, Morizono H, Lin J, Bell P, Jones D, McMenamin D, Yu H, Batshaw ML, and Wilson JM.: Preclinical Evaluation of a Clinical Candidate AAV8 Vector for Ornithine Transcarbamylase (OTC) Deficiency Reveals Functional Enzyme from Each Persisting Vector Genome Molecular Genetics and Metabolism 105 (2): 203-211,2012.

Wang L*, Wang H*, Morizono H, Bell P, Jones D, Lin J, McMenamin D, Yu H, Batshaw ML, and Wilson JM. (Authors contributed equally): Sustained Correction of OTC Deficiency in Spf ash Mice Using Optimized Self-complementary AAV2/8 Vectors Gene Therapy 19 (4): 404-10,2012.

Wang L, Bell P, Lin J, Calcedo R, Tarantal AF, and Wilson JM: AAV8-mediated Hepatic Gene Transfer in Infant Rhesus Monkeys (Macacca mulatta) Molecular Therapy 19 (11): 2012-2020,2011.

Wang L, Louboutin JP, Bell P, Greig J, Li Y, Wu D, and Wilson JM: Muscle-directed Gene Therapy for Hemophilia B with More Efficient and Less Immunogenic AAV Vectors Journal of Thrombosis and Haemostasis 9 (10): 2009-19,2011.

Wang L, Calcedo R, Bell P, Lin J, Grant R, Siegel DL, and Wilson JM.: Impact of Pre-existing Immunity on Gene Transfer to Nonhuman Primate Liver with Adeno-associated Virus 8 Vectors Human Gene Therapy 22 (11): 1389-1401,2011.

Wang L, Calcedo R, Wang H, Bell P, Grant R, Vandenberghe LH, Sanmiguel J, Morizono H, Batshaw ML, and Wilson JM: The Pleiotropic Effects of Natural AAV Infections on Liver-directed Gene Transfer in Macaques Molecular Therapy 18 (1): 126-134,2010.

Wang L*, Wang H*, Bell P, McCarter RJ, He J, Calcedo R, Vandenberghe LH, Morizono H, Batshaw ML, and Wilson JM: Systematic Evaluation of AAV Vectors for Liver-directed Gene Transfer in Murine Models Molecular Therapy 18 (1): 118-125,2010.

Wang L, Figueredo J, Calcedo R, Lin J, and Wilson JM: Cross-presentation of adeno-associated virus serotype 2 capsids activates cytotoxic T cells but does not render hepatocytes effective cytolytic targets. Human Gene Therapy 18 (3): 185-94,2007.

Vandenberghe LH*, Wang L*, Somanathan S, Zhi Y, Figueredo J, Calcedo R, Sanmiguel J, Desai RA, Chen CS, Johnston J, Grant RL, Gao G, and Wilson JM: Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid. Nature Medicine 12 (8): 967-71,2006.

Wang L, Calcedo R, Nichols TC, Bellinger DA, Dillow A, Verma IM, and Wilson JM: Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapy. Blood 105 (8): 3079-86,2005.

Academic Contact Info

125 S. 31st Street
Suite 2000

Philadelphia, PA 19104
Phone: (215) 746-8929