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Kristina Patterson, MD, PhD

Kristina Patterson, MD, PhD Physician

Instructor A of Neurology Clinical Associate of Neurology

Dr. Patterson is employed by Penn Medicine.

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Clinical Specialties


  • Neurology

Programs & Centers:

Clinical Expertise:

  • Abnormal Reflexes
  • Alzheimer's Disease
  • Arm Weakness
  • Arteriovenous Malformations (AVM)
  • Ataxia
  • Bell's Palsy
  • Benign Paroxysmal Positional Vertigo
  • Carotid Stenosis
  • Cerebellar Ataxia
  • Cerebellar Disease
  • Cerebral Aneurysm
  • Cerebrovascular Accident
  • Cervical Dystonia
  • Charcot Marie Tooth Disease (CMT)
  • CNS Vasculitis
  • Cognitive Impairment
  • Concussion
  • Cranial Nerve Injuries
  • Encephalopathies
  • Epilepsy
  • Facial Droop
  • Facial Nerve Pain (Neuralgia)
  • Facial Pain
  • Guillain-Barré Syndrome (GBS)
  • Headache
  • Leg Weakness
  • Lip Droop
  • Lobar Atrophy of Brain
  • Medication Overuse Headache
  • Memory Disorders
  • Movement Disorders
  • Multiple Sclerosis (MS)
  • Muscle Weakness
  • Myasthenia Gravis (MG)
  • Myelitis
  • Nerve Root Pain
  • Nervous System Disorders
  • Neuromuscular Disorders
  • Neuropathy
  • Nonruptured Cerebral Aneurysm
  • Orthostatic Hypotension
  • Paraplegia
  • Paresthesia
  • Parkinson's Disease
  • Peripheral Nerve Disorders
  • Peripheral Neuropathy
  • Periventricular Leukomalacia
  • Positional Vertigo
  • Primary Cerebellar Degeneration
  • Primary Progressive Aphasia
  • Pseudotumor Cerebri
  • Quadriplegia
  • Radiculopathy
  • Sensory Impairment
  • Spinocerebellar Ataxia
  • Spinocerebellar Degeneration
  • Spinocerebellar Diseases
  • Stroke
  • Subarachnoid Hemorrhage
  • Syncope
  • Tetraplegia
  • Tinnitus
  • Torticollis
  • Transient Ischemic Attack
  • Traumatic Brain Injury (TBI)
  • Tremor
  • Trigeminal Nerve Disorders
  • Trigeminal Neuralgia (Tic Douloureux)
  • Unsteady Gait
  • Vertigo
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • OPR Medicare
  • OPR New Jersey Medicaid
  • OPR Pennsylvania Medicaid
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: Northwestern University Feinberg School of Medicine
Residency: Hospital of the University of Pennsylvania


American Academy of Neurology, National American Neurological Associatiohn, National American Society of Cell Biology, National Federation of Clinical Immunology Societies, International International Society of Neuroimmunology, International Pennsylvania Neurological Society, Local Society for Neuroscience, National

Hospital Affiliation

Dr. Patterson is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

My research focuses on the role of of autoimmunity to both myelin antigens and non-myelin antigens (e.g. cell adhesion molecules at nodes of Ranvier) in demyelinating disorders like multiple sclerosis and anti-MOG associated demyelinating disorders.

Selected Publications:

Patterson Kristina, Iglesias Estibaliz, Nasrallah Maclean, González-Álvarez Verónica, Suñol Mariona, Anton Jordi, Saiz Albert, Lancaster Eric, Armangue Thaís: Anti-MOG encephalitis mimicking small vessel CNS vasculitis. Neurology(R) neuroimmunology & neuroinflammation 6 (2): e538,2019.

Li Rui, Patterson Kristina R, Bar-Or Amit: Reassessing B cell contributions in multiple sclerosis. Nature immunology 19 (7): 696-707,2018.

Kristina R Patterson and Eric Lancaster: Hashimoto encephalopathy Medlink Neurology : 2018.

Burnor Elisabeth, Yang Li, Zhou Hao, Patterson Kristina R, Quinn Colin, Reilly Mary M, Rossor Alexander M, Scherer Steven S, Lancaster Eric: Neurofascin antibodies in autoimmune, genetic, and idiopathic neuropathies. Neurology 90 (1): e31-e38,2018.

Patterson Kristina R, Dalmau Josep, Lancaster Eric: Mechanisms of Caspr2 antibodies in autoimmune encephalitis and neuromyotonia. Annals of neurology 83 (1): 40-51,2018.

Prelack Marisa S, Patterson Kristina R, Berger Joseph R: Varicella zoster virus rhombencephalomyelitis following radiation therapy for oropharyngeal carcinoma. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 25 : 164-6,2016.

Ward Sarah M, Himmelstein Diana S, Lancia Jody K, Fu Yifan, Patterson Kristina R, Binder Lester I: TOC1: characterization of a selective oligomeric tau antibody. Journal of Alzheimer's disease : JAD 37 (3): 593-602,2013.

Himmelstein Diana S, Ward Sarah M, Lancia Jody K, Patterson Kristina R, Binder Lester I: Tau as a therapeutic target in neurodegenerative disease. Pharmacology & therapeutics 136 (1): 8-22,2012.

Voss Kellen, Combs Benjamin, Patterson Kristina R, Binder Lester I, Gamblin T Chris: Hsp70 alters tau function and aggregation in an isoform specific manner. Biochemistry 51 (4): 888-98,2012.

Patterson Kristina R, Ward Sarah M, Combs Benjamin, Voss Kellen, Kanaan Nicholas M, Morfini Gerardo, Brady Scott T, Gamblin T Chris, Binder Lester I: Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport. Biochemistry 50 (47): 10300-10,2011.