Find a Doctor or Practice Location

Are you a referring physician?
I am searching for a
Reset Form
Karen C. Patterson, MD

Karen C. Patterson, MD Physician

Medical Director, Pulmonary Diagnostics Laboratory Assistant Professor of Clinical Medicine

Languages spoken:

  • Spanish

Dr. Patterson is a Penn Medicine employed physician.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Patient Comments

Clinical Specialties


  • Pulmonary Medicine

Programs & Centers:

Board Certification:

  • Critical Care Medicine, 2011
  • Internal Medicine, 2007
  • Pulmonary Disease, 2010

Clinical Expertise:

  • Asbestos-related Lung Disease
  • Asthma
  • Beryllium Disease (Berylliosis)
  • Bronchitis
  • Bronchoscopy
  • Chronic Cough
  • Chronic Obstructive Pulmonary Disease (COPD)
  • Cystic Fibrosis
  • Diffuse Alveolar Hemorrhage (DAH)
  • Drug-Induced Pulmonary Disease
  • Emphysema
  • Eosinophilic Granuloma
  • Eosinophilic Pneumonia
  • Hypersensitivity Pneumonitis
  • Idiopathic Pulmonary Fibrosis
  • Interstitial Lung Disease
  • Lung Disease
  • Lung Infections
  • Neuromuscular Disease
  • Nontuberculosis Mycobacteria Lung Disease (NTM)
  • Obstructive Airway Disease
  • Occupational Lung Disease
  • Pleural Effusion
  • Pneumonia
  • Pulmonary Aveolar Proteinosis (PAP)
  • Pulmonary Function Tests (PFT)
  • Pulmonary Rehabilitation
  • Pulmonary Vascular Diseases
  • Pulmonary Vasculitis
  • Respiratory Failure
  • Respiratory Gas Exchange
  • Respiratory Physiology
  • Sarcoidosis
  • Second Opinion
  • Therapeutic Endoscopy
  • Thoracic Malignancies
  • Thoracocentesis (Thoracentesis)
  • Thromboembolism
  • Transplant Medicine
  • Tuberculosis (TB)

Description of Clinical Expertise

Dr. Patterson has expertise in the care of patients with interstitial lung diseases, including sarcoidosis, hypersensitivity pneumonitis, autoimmune-associated lung disease, and idiopathic pulmonary fibrosis. Specific clinical interests include pulmonary fibrosis from sarcoidosis and cardiac sarcoidosis. Dr. Patterson participates in several research studies related to interstitial lung disease and sarcoidosis. In addition, she is the Medical Director of the Pulmonary Diagnostics Laboratory of the Hospital of the University of Pennsylvania, and teaches pulmonary physiology at the Perelman School of Medicine at the University of Pennsylvania.

Practice Locations and Appointments

  • Harron Lung Center

    Perelman Center for Advanced Medicine West Pavilion, 1st Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-7366 (PENN)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Rochester School of Medicine
Residency: Boston Medical Center (Formerly Boston City Hospital)
Fellowship: University of Chicago Medical Center


American College of Chest Physicians, National American Medical Association , National American Medical Association, National American Medical Association, National American Medical Association, National American Thoracic Society, National Americas’ Association of Sarcoidosis and Other Granulomatous Diseases, National

Hospital Affiliation

Dr. Patterson is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Patterson KC, Strek ME: Diagnosis and treatment of pulmonary aspergillosis syndromes Chest 146 (5): 1358-68,2014.

Patterson KC, Huang F, Oldham JM, Bhardwaj N, Hogarth DK, Mokhlesi B.: Excessive daytime sleepiness and obstructive sleep apnea in patients with sarcoidosis Chest 143 (6): 1562-8,2013.

Jensen MA, Patterson KC, Kumar AA, Kumabe M, Franek BS, Niewold TB: Functional genetic polymorphisms in ILT3 are associated with decreased surface expression on dendritic cells and increased serum cytokines in lupus patients. Ann Rheum Dis 72 (4): 596-601,2013.

Patterson KC, Franek BS, Sperling AI, Mueller-Quernheim J, Sweiss NJ, Niewold TB.: Circulating cytokines in sarcoidosis: Phenotype-specific alterations for fibrotic and non-fibrotic pulmonary disease Cytokine 61 (3): 906-11,2013.

Patterson KC, Hogarth K, Husain AN, Sperling AI, Niewold TB: The clinical and immunologic features of pulmonary fibrosis in sarcoidosis Trans Res 160 (5): 321-31,2012.

Sweiss NJ, Zhang W, Franek BS, Kariuki SN, Moller RD, Patterson KC, Bennett P, Girijala LR, Nair V, Baughman RP, Garcia JG, Niewold TB: Linkage of Type I Interferon Activity and TNF-alpha Levels in Serum with Sarcoidosis Manifestations and Ancestry PLos ONE 6 (12): 2011.

Patterson K, Strek M: Allergic Bronchopulmonary Aspergillosis Proc Am Thor Soc 7 : 237-244,2010.

Sweiss N, Patterson K, Sawaqed R, Jabbar U, Korsten P, Hogarth K, Wollman R, Garcia JG, Niewold TB: Rheumatic Manifestation of Sarcoidosis Semin Respir Crit Care Med 31 (4): 463-473,2010.

Patterson K, McShane PJ, Churpek M, Verhoef P: What Fellows Are Reading in Other Journals. Recommended Reading from the University of Chicago Pulmonary and Critical Care Fellows Am J Respir Crit Care Med 182 : 1453-54,2010.

Academic Contact Info

University of Pennsylvania
Perelman School of Medicine
Pulmonary, Allergy & Critical Care Division
3600 Spruce Street

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)