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John Kempen, MD, PhD

John Kempen, MD, PhD Physician

Chief, Ocular Inflammation Service
Director, Ophthalmic Epidemiology
Professor of Ophthalmology
Professor of Epidemiology in Biostatistics and Epidemiology

Dr. Kempen is a Penn Medicine employed physician.

Clinical Specialties

Specialty:

  • Ophthalmology

Programs & Centers:

Board Certification:

  • Ophthalmology, 1997

Clinical Expertise:

  • Ocular Inflammatory Disease
  • Uveitis

Description of Clinical Expertise

Dr. Kempen serves as a regional clinician expert in ocular inflammatory diseases--such as uveitis and scleritis--for the Delaware Valley region of the United States, including Pennsylvania, New Jersey, Delaware and adjacent regions.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Superior Vision Benefit Mgmt, Inc (Block Vision)
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of California, San Diego
Residency: Santa Clara Valley Medical Center
Residency: University of Washington
Fellowship: Johns Hopkins Hospital

Memberships

American Academy of Ophthalmology, National American College of Epidemiology, National American Society of Cataract and Refractive Surgery, National American Uveitis Society, National Association for Research in Vision and Ophthalmology, International Center for Pharmacoepidemiology Research and Training, National Christian Medical and Dental Association, National Greater Philadelphia Ophthalmic Society, Local International Expert Panel on Treatment of CMV Retinitis in Resource-Limited Countries, International International Ocular Inflammation Society, International International Society of Geographical and Epidemiological Ophthalmology (ISGEO), International International Uveitis Study Group, International National Eye Institute / National Institutes of Health, National Penn Center for Orphan Disease Research and Therapy, Local Pennsylvania Academy of Ophthalmology, Local Singapore Ministry of Health, International Society for Clinical Trials, National Standardization of Uveitis Nomenclature Working Group, International Stanford Alumni Association, Local The Johns Hopkins Medical and Surgical Association, Local University of Washington Ophthalmology Alumni Association, Local Wilmer Resident Alumni Association, Local

Hospital Affiliation

Dr. Kempen is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

Dr. Kempen is well-known nationally and internationally as an expert in ocular inflammatory diseases—such as uveitis, scleritis, and others—as well as ocular complications of AIDS. He is the Director of the Penn Ocular Inflammation Service, and Director of Ophthalmic Epidemiology at the Center for Preventive Ophthalmology and Biostatistics. As an expert epidemiologist, he holds a joint appointment in the Department of Biostatistics & Epidemiology, and the Penn Center for Clinical Epidemiology and Biostatistics. Dr. Kempen also is engaged in international research in India and Ethiopia regarding ophthalmic epidemiology and trachoma research.

Clinical Research
-Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study (funded by the National Eye Institute): Dr. Kempen is the national Principal Investigator for this study, the first NIH-sponsored multicenter clinical research study in the field of uveitis.
-Multicenter Uveitis Steroid Treatment (MUST) Trial Follow-up Study(funded by the National Eye Institute): Dr. Kempen serves as International Vice-Chairman for the MUST Network, Protocol Chair for the MUST Trial Follow-up Study, and Director of the Penn Clinical Center enrolling patients in this study.

Key words
Uveitis, iritis, pars planitis, panuveitis, sympathetic ophthalmia, choroiditis, retinitis, neuroretinitis, Vogt-Koyanagi-Harada disease, Fuchs’ heterochromic cyclitis, retinal vasculitis, serpiginous retinochoroiditis, birdshot chorioretinitis, immunosuppressive therapy for eye disease, scleritis, orbital inflammatory disease, ocular complications of AIDS, cytomegalovirus retinitis, acute retinal necrosis, infectious retinitis, toxoplasmic retinitis, trachoma, international ophthalmology, Ethiopia, India

Selected Publications:

Durrani K, Kempen JH, Ying GS, Kacmaz RO, Artornsombudh P, Rosenbaum JT, Suhler EB, Thorne JE, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Foster CS, Site Research Group: Adalimumab for Ocular Inflammation Ocul Immunol Inflamm 22 : 1-8,2016.

Sen HN, Abreu FM, Louis TA, Sugar EA, Altaweel MM, Elner SG, Holbrook JT, Jabs DA, Kim RY, Kempen JH; Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study Research Group: Cataract Surgery Outcomes in Uveitis: The Multicenter Uveitis Steroid Treatment Trial Ophthalmology 123 (1): 2016.

Kempen JH, Van Natta ML, Altaweel MM, Dunn JP, Jabs DA, Lightman SL, Thorne JE, Holbrook JT; Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group: Factors Predicting Visual Acuity Outcome in Intermediate, Posterior and Panuveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial Am J Ophthalmol 160 (6): 1133-1141,2015.

Patel AK, Newcomb CW, Liesegang TL, Pujari SS, Suhler EB, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Sen HN, Artornsombudh P, Kothari S, Kempen JH: Risk of Retinal Neovascularization In Cases of Uveitis Ophthalmology 6420 (15): 01279-8,2015.

Li J, Orlin SE, Revere KE, Kempen JH: Acute onset anterior uveitis after darbepoetin alfa infusion J Ophthalmic Inflamm Infect 5 (1): 31,2015.

Kothari S, Foster CS, Pistilli M, Liesegang TL, Daniel E, Sen HN, Suhler EB, Thorne JE, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Lawrence SD, Kempen JH; Systemic Immunosuppressive Therapy for Eye Diseases Research Group: The Risk of Intraocular Pressure Elevation in Pediatric Noninfectious Uveitis Ophthalmology 122 (10): 1987-2001,2015.

The Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study Research Group. (Writing Committee: Kempen JH (Chair), Altaweel MM, Drye LT, Holbrook JT, Jabs DA, Sugar EA, Thorne JE): Benefits of systemic anti-inflammatory therapy versus fluocinolone acetonide intraocular implant for intermediate, posterior and panuveitis: 54 month results of The Multicenter Uveitis Steroid Treatment Trial (MUST) and Follow-up Study Ophthalmology 122 (10): 1967-75,2015.

The Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study Research Group.(Writing Committee: Kempen JH (Chair), Altaweel MM, Drye LT, Holbrook JT, Jabs DA, Sugar EA, Thorne JE): Quality of life and risks associated with systemic anti-inflammatory therapy versus fluocinolone acetonide intraocular implant for intermediate, posterior or panuveitis: 54 month results of The Multicenter Uveitis Steroid Treatment (MUST) trial and follow-up study Ophthalmology 122 (10): 1979-86,2015.

Subburaman GB, Hariharan L, Ravilla TD, Ravilla RD, Kempen JH: Demand for Tertiary Eye Care Services in Developing Countries Am J Ophthalmol 160 (4): 619-627,2015.

Tomkins-Netzer O, Lightman SL, Drye LT, Kempen JH, Holland GN, Rao NA, Stawell RJ, Vitale A, Jabs DA: Outcome of Treatment of Uveitic Macular Edema: The Multicenter Uveitis Steroid Treatment Trial 2-Year Results Ophthalmology : 2015.

View all publications

Academic Contact Info

Ocular Inflammation Service
Scheie Eye Institute
51 N. 39th St

Philadelphia, PA 19104
Patient appointments: 800-789-PENN (7366)

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