Description of Research Expertise

Pulmonary Hypertension
Heart Failure with Reduced Ejection Fraction
Heart Failure with Preserved Ejection Fraction
Hemodynamics
Cardiopulmonary Exercise Testing
Biomarkers
Echocardiography
Right Ventricular Failure

Selected Publications

Prenner SB, Pillutla R, Yenigalla S, Gaddam S, Lee J, Obeid MJ, Ans AH, Jehangir Q, Kim J, Zamani P, Mazurek JA, Akers SR, Chirinos JA: Serum Albumin is a Marker of Myocardial Fibrosis, Adverse Pulsatile Aortic Hemodynamics and Prognosis in Heart Failure with Preserved Ejection Fraction Journal of the American Heart Association : 2020.

Prenner SB, Kumar A, Zhao L, Cvijic ME, Basso M, Spires T, Li Z, Yarde M, Bhattacharya P, Zamani P, Mazurek J, Wang Z, Seiffert D, Gordon DA, Chirinos JA.: Effect of Serum Albumin Levels in Patients With Heart Failure With Preserved Ejection Fraction (from the TOPCAT Trial). Am J Cardiol : 2019.

Kawut SM, Pinder D, Al-Naamani N, McCormick A, Palevsky HI, Fritz J, Smith KA, Mazurek JA, Doyle MF, MacLean MR, DeMichele A, Mankoff DA.: Fulvestrant for the Treatment of Pulmonary Arterial Hypertension. Annals American Thoracic Society 16 (11): 1456-1459,2019.

Kawut SM, Pinder D, Al-Naamani N, McCormick A, Palevsky HI, Fritz J, Smith KA, Mazurek JA, Doyle MF, MacLean MR, DeMichele A, Mankoff DA.: Fulvestrant for the Treatment of Pulmonary Arterial Hypertension. Ann Am Thorac Soc 16 (11): 1456-1459,2019.

Ruth BK, Bilchick KC, Mysore MM, Mwansa H, Harding WC, Kwon Y, Kennedy JLW, Mazurek JA, Mihalek AD, Smith LA, Mejia-Lopez E, Parker AM, Welch TS, Mazimba S.: Increased Pulmonary-Systemic Pulse Pressure Ratio Is Associated With Increased Mortality in Group 1 Pulmonary Hypertension. Heart Lung Circ 28 (7): 1059-66,2019.

Menachem JN, Reza N, Mazurek JA, Burstein D, Birati EY, Fox A, Kim YY, Molina M, Partington SL, Tanna M, Tobin L, Wald J, Goldberg LR.: Cardiopulmonary Exercise Testing-A Valuable Tool, Not Gatekeeper When Referring Patients With ACHD for Transplant Evaluation. World J Pediatr Congenit Heart Surg 10 (3): 286-291,2019.

Kim YY, Awh K, Acker M, Atluri P, Bermudez C, Crespo M, Diamond JM, Drajpuch D, Forde-Mclean R, Fuller S, Goldberg L, Mazurek J, Mascio C, Menachem JN, Rame E, Ruckdeschel E, Tobin L, Wald J.: Pulmonary arterial hypertension in adults with systemic right ventricles referred for cardiac transplantation. Clin Transplant 33 (4): e13496,2019.

Estephan LE, Genuardi MV, Kosanovich C, Risbano MG, Zhang Y, Petro N, Watson A, Al Aaraj Y, Sembrat J, Rojas M, Goncharov D, Simon M, Goncharova E, Vaidya A, Smith A, Mazurek J, Han Y, Chan SY.: Distinct plasma gradients of microRNA-204 in the pulmonary circulation of patients suffering from WHO Groups I and II pulmonary hypertension. Pulm Circ 9 (2): 2019.

Bhattacharya PT, Troutman GS, Mao F, Fox A, Tanna MS, Zamani P, Grandin W, Menachem JN, Birati EY, Chirinos JA, Mazimba S, Smith A, Kawut SM, Forfia P, Vaidya A, Mazurek JA.: Right ventricular outflow tract velocity time integral-to-pulmonary artery systolic pressure ratio: A noninvasive metric of pulmonary arterial compliance differs across the spectrum of pulmonary hypertension. Pulm Circ 9 (2): 2019.

Negrotto SN, Mazurek JA, Horr SE, John RM, Stevenson LW, Menachem JN: Adverse Effects of Intravenous Diltiazem for Control of Atrial Fibrillation in Patients with Heart Failure J Case Rep Med 8 (4): 2-4,2019.

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Academic Contact Information

Hospital of the University of Pennsylvania
3400 Civic Center Blvd
Perelman Center 11th Floor South 11-179
Philadelphia, PA 19104
Phone: 215-615-0718
Patient appointments: 800-789-7366